Publikation
Thrombolysis in stroke patients aged 80 years and older: Swiss survey of IV thrombolysis
Wissenschaftlicher Artikel/Review - 12.10.2005
Engelter S T, Bogousslavsky J, Sztajzel R, Baumgartner R W, Hungerbühler H J, Tettenborn Barbara, Mattle H P, Michel P, Arnold M, Lüthy R, Müller F, Weder B, Baumann A, Georgiadis D, Sekoranja L, Reichhart M, Lyrer P A
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This databank-based, multicenter study compared all stroke patients with IV tissue plasminogen activator aged > or = 80 years (n = 38) and those < 80 years old (n = 287). Three-month mortality was higher in older patients. Favorable outcome (modified Rankin scale < or = 1) and intracranial hemorrhage (asymptomatic/symptomatic/fatal) were similarly frequent in both groups. Logistic regression showed that stroke severity, time to thrombolysis, glucose level, and history of coronary heart disease independently predicted outcome, whereas age did not.