Publication

Thrombolysis in stroke patients aged 80 years and older: Swiss survey of IV thrombolysis

Journal Paper/Review - Oct 12, 2005

Units
PubMed
Doi

Citation
Engelter S, Bogousslavsky J, Sztajzel R, Baumgartner R, Hungerbühler H, Tettenborn B, Mattle H, Michel P, Arnold M, Lüthy R, Müller F, Weder B, Baumann A, Georgiadis D, Sekoranja L, Reichhart M, Lyrer P. Thrombolysis in stroke patients aged 80 years and older: Swiss survey of IV thrombolysis. Neurology 2005; 65:1795-8.
Type
Journal Paper/Review (English)
Journal
Neurology 2005; 65
Publication Date
Oct 12, 2005
Issn Electronic
1526-632X
Pages
1795-8
Brief description/objective

This databank-based, multicenter study compared all stroke patients with IV tissue plasminogen activator aged > or = 80 years (n = 38) and those < 80 years old (n = 287). Three-month mortality was higher in older patients. Favorable outcome (modified Rankin scale < or = 1) and intracranial hemorrhage (asymptomatic/symptomatic/fatal) were similarly frequent in both groups. Logistic regression showed that stroke severity, time to thrombolysis, glucose level, and history of coronary heart disease independently predicted outcome, whereas age did not.