FDG-PET SUV-max values do not correlate with epidermal growth factor receptor mutation status in lung adenocarcinoma

Publikation

FDG-PET SUV-max values do not correlate with epidermal growth factor receptor mutation status in lung adenocarcinoma

Wissenschaftlicher Artikel/Review - 01.05.2013

Putora Paul Martin, Früh Martin, Müller Joachim

Zitation

Putora P, Früh M, Müller J. FDG-PET SUV-max values do not correlate with epidermal growth factor receptor mutation status in lung adenocarcinoma. Respirology 2013; 18:734-5.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Respirology 2013; 18

Veröffentlichungsdatum

01.05.2013

eISSN (Online)

1440-1843

Seiten

734-5

Kurzbeschreibung/Zielsetzung

Previous reports suggest a correlation between positron emission tomography with fluorodeoxyglucose maximum standardized uptake value (SUVmax) and epidermal growth factor receptor (EGFR) mutation status in lung cancer. We analysed positron emission tomography with fluorodeoxyglucose SUVmax in 14 patients with EGFR mutations, and a control group of 14 subjects with wild-type EGFR adenocarcinomas. The mean SUV value was 10.7 for EGFR-mutated adenocarcinomas and 9.9 for wild-type tumours. There was no correlation between SUV values and EGFR mutation status. Omitting EGFR testing in lung cancers with low SUVmax is not appropriate.