FDG-PET SUV-max values do not correlate with epidermal growth factor receptor mutation status in lung adenocarcinoma

Publication

FDG-PET SUV-max values do not correlate with epidermal growth factor receptor mutation status in lung adenocarcinoma

Journal Paper/Review - May 1, 2013

Putora Paul Martin, Früh Martin, Müller Joachim

Citation

Putora P, Früh M, Müller J. FDG-PET SUV-max values do not correlate with epidermal growth factor receptor mutation status in lung adenocarcinoma. Respirology 2013; 18:734-5.

Type

Journal Paper/Review (English)

Journal

Respirology 2013; 18

Publication Date

May 1, 2013

Issn Electronic

1440-1843

Pages

734-5

Brief description/objective

Previous reports suggest a correlation between positron emission tomography with fluorodeoxyglucose maximum standardized uptake value (SUVmax) and epidermal growth factor receptor (EGFR) mutation status in lung cancer. We analysed positron emission tomography with fluorodeoxyglucose SUVmax in 14 patients with EGFR mutations, and a control group of 14 subjects with wild-type EGFR adenocarcinomas. The mean SUV value was 10.7 for EGFR-mutated adenocarcinomas and 9.9 for wild-type tumours. There was no correlation between SUV values and EGFR mutation status. Omitting EGFR testing in lung cancers with low SUVmax is not appropriate.