A Rare Case of Papillary Thyroid Carcinoma in Marine-Lehnhart Syndrome-Indication for Biopsy of Hot Thyroid Nodules?

Publikation

A Rare Case of Papillary Thyroid Carcinoma in Marine-Lehnhart Syndrome-Indication for Biopsy of Hot Thyroid Nodules?

Wissenschaftlicher Artikel/Review - 12.07.2024

Masjkur Jimmy, Thurnheer Martin, Maas Ole, Schuler Roland, Strey Christopher

Zitation

Masjkur J, Thurnheer M, Maas O, Schuler R, Strey C. A Rare Case of Papillary Thyroid Carcinoma in Marine-Lehnhart Syndrome-Indication for Biopsy of Hot Thyroid Nodules?. JCEM Case Rep 2024; 2:luae116.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

JCEM Case Rep 2024; 2

Veröffentlichungsdatum

12.07.2024

eISSN (Online)

2755-1520

Seiten

luae116

Kurzbeschreibung/Zielsetzung

An uncommon occurrence in which Graves disease (GD) coincides with autonomous functioning thyroid nodules (AFTNs) is termed Marine-Lehnhart syndrome (MLS). While hyperfunctioning nodules in MLS are commonly benign, there exists a rare potential for malignancy. A 41-year-old male patient was initially managed conservatively upon being diagnosed with MLS type 1. However, the emergence of obstructive symptoms prompted a thyroidectomy 4 years after initial presentation. Histological analysis revealed 2 cervical lymph node metastases and papillary thyroid cancer (PTC) within the AFTN.