A Rare Case of Papillary Thyroid Carcinoma in Marine-Lehnhart Syndrome-Indication for Biopsy of Hot Thyroid Nodules?

Publication

A Rare Case of Papillary Thyroid Carcinoma in Marine-Lehnhart Syndrome-Indication for Biopsy of Hot Thyroid Nodules?

Journal Paper/Review - Jul 12, 2024

Masjkur Jimmy, Thurnheer Martin, Maas Ole, Schuler Roland, Strey Christopher

Citation

Masjkur J, Thurnheer M, Maas O, Schuler R, Strey C. A Rare Case of Papillary Thyroid Carcinoma in Marine-Lehnhart Syndrome-Indication for Biopsy of Hot Thyroid Nodules?. JCEM Case Rep 2024; 2:luae116.

Type

Journal Paper/Review (English)

Journal

JCEM Case Rep 2024; 2

Publication Date

Jul 12, 2024

Issn Electronic

2755-1520

Pages

luae116

Brief description/objective

An uncommon occurrence in which Graves disease (GD) coincides with autonomous functioning thyroid nodules (AFTNs) is termed Marine-Lehnhart syndrome (MLS). While hyperfunctioning nodules in MLS are commonly benign, there exists a rare potential for malignancy. A 41-year-old male patient was initially managed conservatively upon being diagnosed with MLS type 1. However, the emergence of obstructive symptoms prompted a thyroidectomy 4 years after initial presentation. Histological analysis revealed 2 cervical lymph node metastases and papillary thyroid cancer (PTC) within the AFTN.