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Increased relative biological effectiveness and periventricular radiosensitivity in proton therapy of glioma patients.
Wissenschaftlicher Artikel/Review - 23.11.2022
Eulitz Jan, Troost Esther G C, Klünder Lauritz, Raschke Felix, Hahn Christian, Schulz Erik, Seidlitz Annekatrin, Thiem Justus, Karpowitz Caroline, Hahlbohm Patricia, Grey Arne, Engellandt Kay, Löck Steffen, Krause Mechthild, Lühr Armin
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Currently, there is an intense debate on variations in intra-cerebral radiosensitivity and relative biological effectiveness (RBE) in proton therapy of primary brain tumours. Here, both effects were retrospectively investigated using late radiation-induced brain injuries (RIBI) observed in follow-up after proton therapy of patients with diagnosed glioma.