Increased relative biological effectiveness and periventricular radiosensitivity in proton therapy of glioma patients.

Publication

Increased relative biological effectiveness and periventricular radiosensitivity in proton therapy of glioma patients.

Journal Paper/Review - Nov 23, 2022

Eulitz Jan, Troost Esther G C, Klünder Lauritz, Raschke Felix, Hahn Christian, Schulz Erik, Seidlitz Annekatrin, Thiem Justus, Karpowitz Caroline, Hahlbohm Patricia, Grey Arne, Engellandt Kay, Löck Steffen, Krause Mechthild, Lühr Armin

Citation

Eulitz J, Troost E, Klünder L, Raschke F, Hahn C, Schulz E, Seidlitz A, Thiem J, Karpowitz C, Hahlbohm P, Grey A, Engellandt K, Löck S, Krause M, Lühr A. Increased relative biological effectiveness and periventricular radiosensitivity in proton therapy of glioma patients. Radiother Oncol 2022; 178:109422.

Type

Journal Paper/Review (English)

Journal

Radiother Oncol 2022; 178

Publication Date

Nov 23, 2022

Issn Electronic

1879-0887

Pages

109422

Brief description/objective

Currently, there is an intense debate on variations in intra-cerebral radiosensitivity and relative biological effectiveness (RBE) in proton therapy of primary brain tumours. Here, both effects were retrospectively investigated using late radiation-induced brain injuries (RIBI) observed in follow-up after proton therapy of patients with diagnosed glioma.