Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E.

Publikation

Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E.

Wissenschaftlicher Artikel/Review - 08.12.2023

Saadat Ali, Gouttenoire Jérôme, Ripellino Paolo, Semela David, Amar Soraya, Frey Beat M, Fontana Stefano, Mdawar-Bailly Elise, Moradpour Darius, Fellay Jacques, Fraga Montserrat, HEV Human Genetics Collaborators

Zitation

Saadat A, Gouttenoire J, Ripellino P, Semela D, Amar S, Frey B, Fontana S, Mdawar-Bailly E, Moradpour D, Fellay J, Fraga M, HEV Human Genetics Collaborators. Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E. Hepatology 2023

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Hepatology 2023

Veröffentlichungsdatum

08.12.2023

eISSN (Online)

1527-3350

Kurzbeschreibung/Zielsetzung

The clinical spectrum of human infection by HEV ranges from asymptomatic to severe acute hepatitis. Furthermore, HEV can cause diverse neurological manifestations, especially Parsonage-Turner syndrome. Here, we used a large-scale human genomic approach to search for genetic determinants of severe clinical presentations of HEV infection.