Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E.

Publication

Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E.

Journal Paper/Review - Dec 8, 2023

Saadat Ali, Gouttenoire Jérôme, Ripellino Paolo, Semela David, Amar Soraya, Frey Beat M, Fontana Stefano, Mdawar-Bailly Elise, Moradpour Darius, Fellay Jacques, Fraga Montserrat, HEV Human Genetics Collaborators

Citation

Saadat A, Gouttenoire J, Ripellino P, Semela D, Amar S, Frey B, Fontana S, Mdawar-Bailly E, Moradpour D, Fellay J, Fraga M, HEV Human Genetics Collaborators. Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E. Hepatology 2023

Type

Journal Paper/Review (English)

Journal

Hepatology 2023

Publication Date

Dec 8, 2023

Issn Electronic

1527-3350

Brief description/objective

The clinical spectrum of human infection by HEV ranges from asymptomatic to severe acute hepatitis. Furthermore, HEV can cause diverse neurological manifestations, especially Parsonage-Turner syndrome. Here, we used a large-scale human genomic approach to search for genetic determinants of severe clinical presentations of HEV infection.