Diagnostic accuracy of plasma glial fibrillary acidic protein for differentiating intracerebral hemorrhage and cerebral ischemia in patients with symptoms of acute stroke.

Publikation

Diagnostic accuracy of plasma glial fibrillary acidic protein for differentiating intracerebral hemorrhage and cerebral ischemia in patients with symptoms of acute stroke.

Wissenschaftlicher Artikel/Review - 28.11.2011

Foerch Christian, Niessner Marion, Back Tobias, Bauerle Michael, De Marchis Gian Marco, Ferbert Andreas, Grehl Holger, Hamann Gerhard F, Jacobs Andreas, Kastrup Andreas, Klimpe Sven, Palm Frederick, Thomalla Götz, Worthmann Hans, Sitzer Matthias, BE FAST Study Group

Zitation

Foerch C, Niessner M, Back T, Bauerle M, De Marchis G, Ferbert A, Grehl H, Hamann G, Jacobs A, Kastrup A, Klimpe S, Palm F, Thomalla G, Worthmann H, Sitzer M, BE FAST Study Group. Diagnostic accuracy of plasma glial fibrillary acidic protein for differentiating intracerebral hemorrhage and cerebral ischemia in patients with symptoms of acute stroke. Clin Chem 2011; 58:237-45.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Clin Chem 2011; 58

Veröffentlichungsdatum

28.11.2011

eISSN (Online)

1530-8561

Seiten

237-45

Kurzbeschreibung/Zielsetzung

Glial fibrillary acidic protein (GFAP) is a biomarker candidate indicative of intracerebral hemorrhage (ICH) in patients with symptoms of acute stroke. GFAP is released rapidly in the presence of expanding intracerebral bleeding, whereas a more gradual release occurs in ischemic stroke. In this study the diagnostic accuracy of plasma GFAP was determined in a prospective multicenter approach.