Publication

Diagnostic accuracy of plasma glial fibrillary acidic protein for differentiating intracerebral hemorrhage and cerebral ischemia in patients with symptoms of acute stroke.

Journal Paper/Review - Nov 28, 2011

Units
PubMed
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Citation
Foerch C, Niessner M, Back T, Bauerle M, De Marchis G, Ferbert A, Grehl H, Hamann G, Jacobs A, Kastrup A, Klimpe S, Palm F, Thomalla G, Worthmann H, Sitzer M, BE FAST Study Group. Diagnostic accuracy of plasma glial fibrillary acidic protein for differentiating intracerebral hemorrhage and cerebral ischemia in patients with symptoms of acute stroke. Clin Chem 2011; 58:237-45.
Type
Journal Paper/Review (English)
Journal
Clin Chem 2011; 58
Publication Date
Nov 28, 2011
Issn Electronic
1530-8561
Pages
237-45
Brief description/objective

Glial fibrillary acidic protein (GFAP) is a biomarker candidate indicative of intracerebral hemorrhage (ICH) in patients with symptoms of acute stroke. GFAP is released rapidly in the presence of expanding intracerebral bleeding, whereas a more gradual release occurs in ischemic stroke. In this study the diagnostic accuracy of plasma GFAP was determined in a prospective multicenter approach.