Publikation

Transfer of antiretroviral drugs into breastmilk: a prospective study from the Swiss Mother and Child HIV Cohort Study.

Wissenschaftlicher Artikel/Review - 28.11.2022

Bereiche
PubMed
DOI
Kontakt

Zitation
Aebi-Popp K, Kahlert C, Crisinel P, Decosterd L, Saldanha S, Hoesli I, Martinez de Tejada B, Duppenthaler A, Rauch A, Marzolini C, ĀăąĆĉČĎ Ā. Transfer of antiretroviral drugs into breastmilk: a prospective study from the Swiss Mother and Child HIV Cohort Study. J Antimicrob Chemother 2022; 77:3436-3442.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
J Antimicrob Chemother 2022; 77
Veröffentlichungsdatum
28.11.2022
eISSN (Online)
1460-2091
Seiten
3436-3442
Kurzbeschreibung/Zielsetzung

In 2018, Switzerland changed its guidelines to support women living with HIV wishing to breastfeed. The exposure of antiretroviral drugs (ARVs) in breastmilk and the ingested daily dose by the breastfed infant are understudied, notably for newer ARVs. This study aimed to quantify ARV concentrations in maternal plasma and breastmilk to determine the milk/plasma ratio, to estimate daily infant ARV dose from breastfeeding and to measure ARV concentrations in infants.