Projekt
Preoperative chemoradiotherapy vs. chemotherapy alone in non-small cell lung cancer (NSCLC) patients with mediastinal lymph node metastases (stage IIIA, N2): A randomized prospective phase III trial
Automatisch geschlossen · 2001 bis 2011
Früh Martin, Pfister Bogumila
Art
Klinische Forschung
Reichweite
Multizentrisch, KSSG als teilnehmendes Zentrum
Bereiche
Status
Automatisch geschlossen
Start
2001
Ende
2011
Studiendesign
phase III trial
Schlagwörter (Tags)
NSCLC IIIA praeoperativ, CT vs. CRT
Projektpartner
PD Dr. med. Miklos Pless, Winterthur
Prof. Dr. Roger Stupp, Lausanne
Kurzbeschreibung/Zielsetzung
The main objective of this trial is to compare feasibility and efficacy of sequential neoadjuvant chemoradiotherapy with 44 Gy concomitant boost to neoadjuvant chemotherapy alone. Secondary objectives are to assess the value of PET in predicting pathological response and event-free survival in stage IIIA NSCLC, and an economic
evaluation of the two regimens.