Projekt

The Neuroprotective Effect of Lamotrigine and Interferon Beta 1a in Patients With Relapsing-Remitting Multiple Sclerosis

Automatisch geschlossen · 2009 bis 2011

Art
Klinische Forschung
Reichweite
Monozentrisch am KSSG
Bereiche
Status
Automatisch geschlossen
Start
2009
Ende
2011
Finanzierungsart
Industrie
Studiendesign
randomized, placebo-controlled, MRI rater blinded study
Schlagwörter (Tags)
MS, neuroprotection, phase II, interferon-beta
Webseite
Kurzbeschreibung/Zielsetzung

Randomized, Placebo-Controlled Phase II Monocentric Trial for the Neuroprotective Effect of Lamotrigine Plus Interferon Beta 1a 30mcg Once Weekly Intramuscular in Patients With Relapsing-Remitting Multiple Sclerosis.

Primary Outcome Measures:
N-Acetyl-Aspartate / creatine - quotient in normal appearing white matter by MR-spectroscopy [ Time Frame: 12 months ]
Safety of lamotrigine in combination with interferon beta 1a (30 mcg) once weekly intramuscular. [ Time Frame: 6 months, 12 months ]