Dr Florent Baty
Leitende(r) Wissenschaftler/in
Pneumologie und Schlafmedizin · Dept. I
Predictive and prognostic value of integrated exon-level expression to approach drug-response and resistance to EGFR-targeted treatment in non-small cell lung cancer
01.01.2015Activating mutations in lung cancer are targeted by a series of molecularly targeted therapies. Patients harboring such mutations can receive significant benefit from these therapies. However a proportion of patients without activating mutations can...
Grundlagenforschung - 01.01.2015 - 31.12.2016
Automatisch geschlossen
Projektleitung: Baty Florent
Mitarbeiter/innen: Franzini Anca, Früh Martin, Jörger Markus, Brutsche Martin
Airway microbiota resistome in CF - impact on clinical management
01.09.2014Cystic Fibrosis is a deadly genetic disease mainly due to chronic bacterial colonization and recurrent bacterial infections of the lungs. It has often been documented that once a certain microbial species such as Pseudomonas aeruginosa establishes, t...
Grundlagenforschung - 01.09.2014 - 31.12.2016
Automatisch geschlossen
Projektleitung: Baty Florent
Mitarbeiter/innen: Brutsche Martin, Kahlert Christian, Von Mering Christian, Vyas Rounak
Blood pressure variability during the 6-minute walk test in patients with Chronic Obstructive Pulmonary Disease (COPD): A case-control study
10.03.2014The proposed study will compare vSBP values during physical exercise between patients with COPD and age- and gender-matched controls. We hypothesize that vSBP during the 6MWT is increased in patients with COPD compared to age- and gender matched cont...
Grundlagenforschung - 10.03.2014 - 01.06.2015
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Projektleitung: van Gestel Arnoldus J R
Mitarbeiter/innen: Baty Florent, Brutsche Martin, Gajic Andreja
Thorakoskopische Handheld-SPECT gesteuerte Ektomie von radioaktiv-markierten pulmonalen Rundherden
01.11.2013Bei 30-40 Patienten pro Jahr wird im Kantonsspital St.Gallen ein pulmonaler Rundherd entfernt. Deutlich vorteilhafter gegenüber der offenen Operation ist die thorakoskopische Resektion. Einschränkungen sind die Auffindbarkeit und Resezierbarkeit von...
Klinische Forschung - 01.11.2013 - 31.10.2015
Automatisch geschlossen
Projektleitung: Müller Joachim
Mitarbeiter/innen: Zeisel Christoph, Schneider Tino, Baty Florent, Eberl Andreas
Genome-wide Gene/Exon expression analysis of late stage NSCLC treated by Erlotinib /Bevacizumab: role of tumor-stroma interactions
01.02.2013Genome-wide Gene/Exon expression analysis of late stage NSCLC treated by Erlotinib /Bevacizumab: role of tumor-stroma interactions
Grundlagenforschung - 01.02.2013 - 01.06.2015
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Projektleitung: Baty Florent
Mitarbeiter/innen: Brutsche Martin, Oliver Dürr, Franzini Anca
Systems biology approach to molecularly characterize the lung cancer microenvironment
01.01.2013Lung cancer is the most frequent cause of death in cancer patients in industrialized countries. Most patients with advanced nonsmall cell lung cancer (NSCLC) do not respond to the current treatment schemes indicating that the basic mechanisms of tumo...
Grundlagenforschung - 01.01.2013 - 31.12.2014
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Projektleitung: Ludewig Burkhard, Brutsche Martin
Mitarbeiter/innen: Baty Florent, Novkovic Mario, Onder Lucas
Improved adherence to CPAP by Telemetric Support in Newly diagnosed OSAS Patients
01.01.2013Introduction: The acceptance of positive airway pressure therapy (CPAP) within the first month is a critical aspect of successful OSAS therapy. Telemedicine is a novel tool to supervise CPAP use at patient's home. We report 30-day results of a pilot...
Grundlagenforschung - 01.01.2013 - 01.03.2013
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Projektleitung: Schoch Otto, Brutsche Martin
Mitarbeiter/innen: Baty Florent, Niedermann Jolanda, Rüdiger Jochen
Telemedicine to enhance CPAP adherence in OSAS - A randomized placebo-controlled prospective study
01.01.2013We hypothesize that the use of telemedicine combined with support interventions by short messages, telephone calls and ambulatory visits to control CPAP treatment in OSAS patients during the first month improves adherence and reduces unresolved side...
Klinische Forschung - 01.01.2013 - 31.12.2015
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Projektleitung: Schoch Otto
Mitarbeiter/innen: Baty Florent, Niedermann Jolanda, Brutsche Martin
Integrative Translational Research Network for Lung Cancer (ITRNLC)
01.10.2012Lung cancer remains a health issue with a dismal outcome and evolution in the search of new prognostic markers and therapeutic approaches. To improve research efforts interdisciplinary and multicenter research networks are needed. For competitive tra...
Grundlagenforschung - 01.10.2012 - 31.12.2015
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Projektleitung: Brutsche Martin, Putora Paul Martin
Mitarbeiter/innen: Baty Florent
The significance of Defensin alpha 4 in the pathophysiology of the adrenal insufficiency in inflammatory lung diseases
01.09.2012The pathophysiology of the adrenal insufficiency of patients with critical diseases remains unclear. In a prior exploratory study investigating patients with exacerbation of chronic obstructive pulmonary disease (COPD), we demonstrated a highly signi...
Grundlagenforschung - 01.09.2012 - 01.09.2013
Abgebrochen
Projektleitung: Rüdiger Jochen
Mitarbeiter/innen: Baty Florent, Bilz Stefan, Lehmann Natalie, Brutsche Martin
Significant reduction of AECOPD hospitalizations after implementation of a public smoking ban in Graubünden, Switzerland
01.09.2012Background Only few studies have examined the effect of public smoking bans on respiratory conditions. These showed reduced admission rates for different respiratory diseases. Objective of the present study was to evaluate the effect of the public sm...
Grundlagenforschung - 01.09.2012 - 01.06.2013
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Projektleitung: Baty Florent, Brutsche Martin
Mitarbeiter/innen: Dusemund Frank
Circulating micro-RNA profiling in patients with advanced non-squamous non small-cell lung cancer receiving bevacizumab/erlotinib first-line treatment followed by platinum-based chemotherapy at disease progression (SAKK 19/05)
01.04.2012Background: This study was initiated by the Swiss Group for Clinical Cancer Research (SAKK) 19/05 study to assess the predictive and prognostic value of circulating miRNA profiles from peripheral blood of patients with non-squamous non small-cell lu...
Grundlagenforschung - 01.04.2012 - 01.09.2013
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Projektleitung: Brutsche Martin
Mitarbeiter/innen: Jörger Markus, Zappa Francesco, Gautschi Oliver, Pless Miklos, Ochsenbein Adrian, Bubendorf Lukas, von Moos Roger, Betticher Daniel, Stahel Rolph, Früh Martin, Baty Florent
Pleural pharmacokinetics of moxifloxacin and amoxicillin-clavulanate in the context of parapneumonic pleural effusions and empyema
01.12.2011The main objective of the study is the characterization of the PK profiles of moxifloxacin and amoxicillin clavulanate in the pleural fluid of patients with parapneumonic effusions using population PK-analysis. Intra- and interpatient variability wil...
Klinische Forschung - 01.12.2011 - 31.12.2012
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Projektleitung: Brutsche Martin
Mitarbeiter/innen: Boggian Katia, Jörger Markus, Baty Florent, Ruedlinger Luzia
St. Gallen Lung Biopsy Biobank - An interdisciplinary collaboration in pulmonary medicine
01.09.2011The current project proposes to create a tissue and blood sample collection (biobank) of all patients willing to give informed consent, who are undergoing bronchoscopy and/or surgical lug resection in their diagnostic pathway for any pulmonary diseas...
Grundlagenforschung - 01.09.2011 - 31.12.2030
Automatisch geschlossen
Projektleitung: Brutsche Martin
Mitarbeiter/innen: Baty Florent
Comorbidities and burden of COPD: a population based case-control study
01.06.2011COPD is associated with a relevant burden of disease and a high mortality worldwide. Only recently, the importance of comorbidities of COPD has been recognized. Studies postulated an association with inflammatory conditions potentially sharing pathog...
Grundlagenforschung - 01.06.2011 - 01.06.2013
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Projektleitung: Baty Florent, Brutsche Martin
Mitarbeiter/innen: Putora Paul Martin, Isenring Bruno, Blum Torsten
Eine randomisierte, aktiv kontrollierte, doppelblinde, Double-Dummy, multizentrische Parallelgruppen-Studie zum Vergleich der Wirksamkeit und Sicherheit von 2,5µg und 5 µg Tiotropium-Inhalations-Lösung, inhaliert mittels Respimat®-Inhalator gegenüber Tiotropium-Inhalationskapseln 18µg, inhaliert mittels HandiHaler® TIOSPIR-Studie
15.05.2010A Randomized, Active-controlled, Double-blind, Double-dummy, Parallel Group Design, Multi-center Trial to Compare the Efficacy and Safety of 2.5 µg and 5 µg Tiotropium Inhalation Solution Delivered by the Respimat Inhaler With Tiotropium Inhalation C...
Klinische Forschung - 15.05.2010 - 15.12.2013
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Projektleitung: Brutsche Martin
Mitarbeiter/innen: Baty Florent
An extension study to QTI571A2301 to evaluate the longterm safety, tolerability and efficacy of oral QTI571 (imatinib) in the treatment of severe pulmonary arterial hypertension: IMPRESS Extension
01.12.2009
Klinische Forschung - 01.12.2009 - 01.12.2011
Abgebrochen
Projektleitung: Brutsche Martin
Mitarbeiter/innen: Baty Florent
Randomized placebo-controled, double-blind exploratory trial of Bosentan for steroid resistant pulmonary sarcoidosis - the BOSSA study
01.07.2007
Klinische Forschung - 01.07.2007 - 01.07.2013
Abgeschlossen
Projektleitung: Brutsche Martin
Mitarbeiter/innen: Baty Florent, Burger Barbara