Karin Eugster
TOLERAGE: Normalisation of immune reactivity in old age – from basic mechanisms to clinical application
01.04.2008Reconstitution of normal immune function in old age is generally based on boosting the response against foreign antigens, e.g. infectious microorganisms. Our focus, however, will be to normalise immune reactivity by correcting the immune dysregulati...
Grundlagenforschung - 01.04.2008 - 30.09.2012
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Projektleitung: Ludewig Burkhard, Thiel Volker
Mitarbeiter/innen: Cervantes-Barragan Luisa, Eugster Karin
Impact of immune regulation on virus-induced chronic CNS inflammation and demyelination
01.01.2008Background: Multiple sclerosis (MS) is an important disease affecting young adults. Epidemiological studies indicate that this disease critically depends on environmental factors, including infectious agents. It appears that infections with a variety...
Grundlagenforschung - 01.01.2008 - 31.12.2008
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Projektleitung: Ludewig Burkhard
Mitarbeiter/innen: Cervantes-Barragan Luisa, Eugster Karin
Role of professional and non-professional antigen presenting cells in cardiovascular immunopathological disease
01.04.2007The importance of chronic inflammatory processes in the pathogenesis of cardiovascular diseases is now widely recognized. Atherosclerosis and autoimmune myocarditis are prototypical diseases illustrating the detrimental effects of constant immune act...
Grundlagenforschung - 01.04.2007 - 31.03.2010
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Projektleitung: Ludewig Burkhard
Mitarbeiter/innen: Eugster Karin, Nindl Veronika
AIDS-CoVAC: Generation of a coronavirus-based multigene AIDS vaccine and evaluation in a preclinical SIV model
01.12.2006Coronaviruses spread via mucosal surfaces and can infect dendritic cells. These features and their exceptional transcription strategy make them extremely promising candidate vaccine vectors to overcome known problems of current HIV vaccine approaches...
Grundlagenforschung - 01.12.2006 - 31.05.2009
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Projektleitung: Ludewig Burkhard, Thiel Volker
Mitarbeiter/innen: Eugster Karin, Cervantes-Barragan Luisa, Makia Divine