Reconstitution of normal immune function in old age is generally based on boosting the response against foreign antigens, e.g. infectious microorganisms. Our focus, however, will be to normalise immune reactivity by correcting the immune dysregulati...

Fundamental Research - Apr 1, 2008 - Sep 30, 2012

Completed

Project leader: Ludewig Burkhard, Thiel Volker
Members: Cervantes-Barragan Luisa, Eugster Karin

Background: Multiple sclerosis (MS) is an important disease affecting young adults. Epidemiological studies indicate that this disease critically depends on environmental factors, including infectious agents. It appears that infections with a variety...

Fundamental Research - Jan 1, 2008 - Dec 31, 2008

Completed

Project leader: Ludewig Burkhard
Members: Cervantes-Barragan Luisa, Eugster Karin

The importance of chronic inflammatory processes in the pathogenesis of cardiovascular diseases is now widely recognized. Atherosclerosis and autoimmune myocarditis are prototypical diseases illustrating the detrimental effects of constant immune act...

Fundamental Research - Apr 1, 2007 - Mar 31, 2010

Completed

Project leader: Ludewig Burkhard
Members: Eugster Karin, Nindl Veronika

Coronaviruses spread via mucosal surfaces and can infect dendritic cells. These features and their exceptional transcription strategy make them extremely promising candidate vaccine vectors to overcome known problems of current HIV vaccine approaches...

Fundamental Research - Dec 1, 2006 - May 31, 2009

Completed

Project leader: Ludewig Burkhard, Thiel Volker
Members: Eugster Karin, Cervantes-Barragan Luisa, Makia Divine