PD Dr. med. Dr. phil. Christine Bernsmeier
STAR LIGHT Study: XBB.1.5 COVID-19 mRNA Vaccines Boost Systemic but Not Mucosal Immunity Against the SARS-CoV-2 JN.1 Variant in Patients with Chronic Liver Disease.
Woelfel S, Junker D, Bergamin I, Meyer-Herbon P, Stillhard R, Graf N, Leinenkugel G, Dütschler J, König M, Häuptle R, Zwyssig S, Krieger-Grübel C, Truniger S, Koller S, Metzger-Peter K, Frei N, Genetics And Observational Subarachnoid Haemorrhage Gosh Study Investigators, Albrich W, Friedrich M, Bernsmeier C, Niess J, Korte W, Bürgi J, Dulovic A, Schneiderhan-Marra N, Semela D, Brand S. STAR LIGHT Study: XBB.1.5 COVID-19 mRNA Vaccines Boost Systemic but Not Mucosal Immunity Against the SARS-CoV-2 JN.1 Variant in Patients with Chronic Liver Disease. Vaccines (Basel) 2024; 12
31.10.2024STAR LIGHT Study: XBB.1.5 COVID-19 mRNA Vaccines Boost Systemic but Not Mucosal Immunity Against the SARS-CoV-2 JN.1 Variant in Patients with Chronic Liver Disease.
31.10.2024Vaccines (Basel) 2024; 12
Woelfel Simon, Junker Daniel, Bergamin Irina, Meyer-Herbon Pamela, Stillhard Roman, Graf Nicole, Leinenkugel Georg, Dütschler Joel, König Marius, Häuptle Rahel, Zwyssig Sarah, Krieger-Grübel Claudia, Truniger Samuel, Koller Seraina, Metzger-Peter Katline, Frei Nicola Fabian, Genetics And Observational Subarachnoid Haemorrhage Gosh Study Investigators, Albrich Werner, Friedrich Matthias, Bernsmeier Christine, Niess Jan-Hendrik, Korte Wolfgang C, Bürgi Justus J, Dulovic Alex, Schneiderhan-Marra Nicole, Semela David, Brand Stephan
Real-life experience of chronic hepatitis C treatment in Switzerland: a retrospective analysis.
Moschouri E, Salemme G, Baserga A, Cerny A, Deibel A, Muellhaupt B, Meier M, Bernsmeier C, Ongaro M, Negro F, Grosjean M, Clerc O, Künzler-Heule P, Semela D, Hobi G, Stickel F, Mathieu A, Mdawar-Bailly E, Faouzi M, Moradpour D, Fraga M. Real-life experience of chronic hepatitis C treatment in Switzerland: a retrospective analysis. Swiss Med Wkly 2024; 154:3698.
24.06.2024Real-life experience of chronic hepatitis C treatment in Switzerland: a retrospective analysis.
24.06.2024Swiss Med Wkly 2024; 154:3698
Moschouri Eleni, Salemme Gloria, Baserga Adriana, Cerny Andreas, Deibel Ansgar, Muellhaupt Beat, Meier Marie-Anne, Bernsmeier Christine, Ongaro Marie, Negro Francesco, Grosjean Marielle, Clerc Olivier F, Künzler-Heule Patrizia, Semela David, Hobi Gabriel, Stickel Felix, Mathieu Adeline, Mdawar-Bailly Elise, Faouzi Mohamed, Moradpour Darius, Fraga Montserrat
Epidemiology, clinical features and management of autoimmune hepatitis in Switzerland: a retrospective and prospective cohort study.
Ludz C, Stirnimann G, Semela D, Mertens J, Kremer A, Filipowicz Sinnreich M, Sokollik C, Bernsmeier C, Bresson-Hadni S, McLin V, Rock N, Braegger C, Posovszky C, Müller P, Cremer M, De Gottardi A, Galante A, Furlano R, Righini-Grunder F, Becker B, Böhm S, Heyland K, Nydegger A, Limoni C, Vergani D, Mieli-Vergani G, Di Bartolomeo C, Cerny A, Terziroli Beretta-Piccoli B. Epidemiology, clinical features and management of autoimmune hepatitis in Switzerland: a retrospective and prospective cohort study. Swiss Med Wkly 2023; 153:40102.
31.08.2023Epidemiology, clinical features and management of autoimmune hepatitis in Switzerland: a retrospective and prospective cohort study.
31.08.2023Swiss Med Wkly 2023; 153:40102
Ludz Christine, Stirnimann Guido, Semela David, Mertens Joachim C, Kremer Andreas E, Filipowicz Sinnreich Magdalena, Sokollik Christiane, Bernsmeier Christine, Bresson-Hadni Solange, McLin Valérie, Rock Nathalie, Braegger Christian P, Posovszky Carsten, Müller Pascal, Cremer Matthias, De Gottardi Andrea, Galante Antonio, Furlano Raoul, Righini-Grunder Franziska, Becker Björn, Böhm Stephan, Heyland Klaas, Nydegger Andreas, Limoni Costanzo, Vergani Diego, Mieli-Vergani Giorgina, Di Bartolomeo Claudia, Cerny Andreas, Terziroli Beretta-Piccoli Benedetta
AXL expression on homeostatic resident liver macrophages is reduced in cirrhosis following GAS6 production by hepatic stellate cells.
Pop O, Geng A, Flint E, Singanayagam A, Ercan C, Possamai L, Patel V, Künzler-Heule P, Meier M, Soysal S, Hruz P, Kollmar O, Tatham K, Ward J, Mullhaupt B, Weber A, Wendon J, Niess J, Heim M, Semela D, Weston C, Antoniades C, Terracciano L, Triantafyllou E, Brenig R, Bernsmeier C. AXL expression on homeostatic resident liver macrophages is reduced in cirrhosis following GAS6 production by hepatic stellate cells. Cell Mol Gastroenterol Hepatol 2023
31.03.2023AXL expression on homeostatic resident liver macrophages is reduced in cirrhosis following GAS6 production by hepatic stellate cells.
31.03.2023Cell Mol Gastroenterol Hepatol 2023
Pop Oltin-Tiberiu, Geng Anne, Flint Emilio, Singanayagam Arjuna, Ercan Caner, Possamai Lucia A, Patel Vishal C, Künzler-Heule Patrizia, Meier Marie-Anne, Soysal Savas D, Hruz Petr, Kollmar Otto, Tatham Kate C, Ward Josie K, Mullhaupt Beat, Weber Achim, Wendon Julia, Niess Jan Hendrik, Heim Markus, Semela David, Weston Christopher J, Antoniades Charalambos G, Terracciano Luigi, Triantafyllou Evangelos, Brenig Robert, Bernsmeier Christine
Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis
Brenig R, Antoniades C, Wendon J, Heim M, Ludewig B, Weston C, Duong F, Semela D, Brand S, Boldanova T, Künzler-Heule P, Cupovic J, Besse L, Pérez Shibayama C, Singanayagam A, Geng A, Triantafyllou E, Pop O, Bernsmeier C. Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis. Life Sci Alliance 2019; 3
10.12.2019Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis
10.12.2019Life Sci Alliance 2019; 3
Brenig Robert, Antoniades Charalambos G, Wendon Julia, Heim Markus H, Ludewig Burkhard, Weston Christopher J, Duong François Ht, Semela David, Brand Stephan, Boldanova Tuyana, Künzler-Heule Patrizia, Cupovic Jovana, Besse Lenka, Pérez Shibayama Christian Ivan, Singanayagam Arjuna, Geng Anne, Triantafyllou Evangelos, Pop Oltin, Bernsmeier Christine
CD14+CD15-HLA-DR- myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure
Bernsmeier C, Wendon J, Thursz M, Adams D, Weston C, Tidswell R, Nathwani R, Khamri W, Pop O, Patel V, Singanayagam A, Lebosse F, Brenig R, Triantafyllou E, Antoniades C. CD14+CD15-HLA-DR- myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure. Gut 2017
07.06.2017CD14+CD15-HLA-DR- myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure
07.06.2017Gut 2017
Bernsmeier Christine, Wendon Julia A, Thursz Mark R, Adams David H, Weston Christopher J, Tidswell Robert, Nathwani Rooshi, Khamri Wafa, Pop Oltin T, Patel Vishal C, Singanayagam Arjuna, Lebosse Fanny J, Brenig Robert, Triantafyllou Evangelos, Antoniades Charalambos Gustav
MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure
Triantafyllou E, Stamataki Z, Curbishley S, Ma Y, Wilson I, Coen M, Woollard K, Quaglia A, Wendon J, Thursz M, Adams D, Weston C, Abeles R, Patel V, Yuksel M, Pop O, Possamai L, Wilhelm A, Liaskou E, Singanayagam A, Bernsmeier C, Khamri W, Petts G, Dargue R, Davies S, Tickle J, Antoniades C. MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure. Gut 2017
27.04.2017MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure
27.04.2017Gut 2017
Triantafyllou Evangelos, Stamataki Zania, Curbishley Stuart M, Ma Yun, Wilson Ian D, Coen Muireann, Woollard Kevin J, Quaglia Alberto, Wendon Julia, Thursz Mark R, Adams David H, Weston Chris J, Abeles Robin D, Patel Vishal C, Yuksel Muhammed, Pop Oltin T, Possamai Lucia A, Wilhelm Annika, Liaskou Evaggelia, Singanayagam Arjuna, Bernsmeier Christine, Khamri Wafa, Petts Gemma, Dargue Rebecca, Davies Scott P, Tickle Joseph, Antoniades Charalambos G
Increased Expression of CTLA4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure
Khamri W, Lebosse F, Auzinger G, Bernal W, Willars C, Weston C, Lombardi G, Wendon J, Thursz M, Possamai L, Kudo N, Abeles R, Hou T, Anderson A, El-Masry A, Triantafyllou E, Bernsmeier C, Larsen F, Singanayagam A, Antoniades C. Increased Expression of CTLA4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure. Gastroenterology 2017
28.03.2017Increased Expression of CTLA4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure
28.03.2017Gastroenterology 2017
Khamri Wafa, Lebosse Fanny, Auzinger Georg, Bernal William, Willars Christopher, Weston Christopher J, Lombardi Giovanna, Wendon Julia, Thursz Mark, Possamai Lucia A, Kudo Nobuaki, Abeles Robin D, Hou Tie Zheng, Anderson Amy E, El-Masry Ahmed, Triantafyllou Evangelos, Bernsmeier Christine, Larsen Fin S, Singanayagam Arjuna, Antoniades Charalambos G
Liver dendritic cells and NAFLD evolution: A remaining open issue
Bernsmeier C, Albano E. Liver dendritic cells and NAFLD evolution: A remaining open issue. J Hepatol 2017
23.02.2017Liver dendritic cells and NAFLD evolution: A remaining open issue
23.02.2017J Hepatol 2017
Bernsmeier Christine, Albano Emanuele
Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation
Bernsmeier C, Heim M, Marra F, Tornillo L, Semela D, Muscogiuri G, Krol I, Makowska Z, Provenzano A, Dill M, Duong F. Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation. Lab Invest 2016; 96:972-80.
18.07.2016Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation
18.07.2016Lab Invest 2016; 96:972-80
Bernsmeier Christine, Heim Markus H, Marra Fabio, Tornillo Luigi, Semela David, Muscogiuri Giovanna, Krol Ilona, Makowska Zuzanna, Provenzano Angela, Dill Michael T, Duong Francois H T
Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase
Vergis N, James S, Foxton M, Hogan B, Foster G, O'Brien A, Ma Y, Shawcross D, Wendon J, Antoniades C, Abeles R, Ryan J, Khamri W, Beale K, Sadiq F, Aletrari M, Moore C, Atkinson S, Bernsmeier C, Possamai L, Petts G, Thursz M. Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase. Gut 2016
09.02.2016Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase
09.02.2016Gut 2016
Vergis Nikhil, James Sarah, Foxton Matthew, Hogan Brian, Foster Graham R, O'Brien Alastair J, Ma Yun, Shawcross Debbie L, Wendon Julia A, Antoniades Charalambos G, Abeles Robin D, Ryan Jennifer M, Khamri Wafa, Beale Kylie, Sadiq Fouzia, Aletrari Mina O, Moore Celia, Atkinson Stephen R, Bernsmeier Christine, Possamai Lucia A, Petts Gemma, Thursz Mark R
Neutrophil Toll-Like Receptor 9 Expression and the Systemic Inflammatory Response in Acetaminophen-Induced Acute Liver Failure
Manakkat Vijay G, Ma Y, Wendon J, Chokshi S, Willars C, Auzinger G, Bernal W, Taylor N, Markwick L, Tranah T, McPhail M, Riva A, Bernsmeier C, Patel V, Ramage S, Abeles R, Ryan J, Shawcross D. Neutrophil Toll-Like Receptor 9 Expression and the Systemic Inflammatory Response in Acetaminophen-Induced Acute Liver Failure. Crit Care Med 2016; 44:43-53.
01.01.2016Neutrophil Toll-Like Receptor 9 Expression and the Systemic Inflammatory Response in Acetaminophen-Induced Acute Liver Failure
01.01.2016Crit Care Med 2016; 44:43-53
Manakkat Vijay Godhev K, Ma Yun, Wendon Julia A, Chokshi Shilpa, Willars Chris, Auzinger Georg, Bernal William, Taylor Nicholas J, Markwick Lee J L, Tranah Thomas H, McPhail Mark J W, Riva Antonio, Bernsmeier Christine, Patel Vishal, Ramage Stephen, Abeles Robin D, Ryan Jennifer M, Shawcross Debbie L
Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: A Comparison with Healthy Controls
Bernsmeier C, Weisskopf D, Pflueger M, Mosimann J, Campana B, Terracciano L, Beglinger C, Heim M, Cajochen C. Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: A Comparison with Healthy Controls. PloS one 2015; 10:e0143293.
17.11.2015Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: A Comparison with Healthy Controls
17.11.2015PloS one 2015; 10:e0143293
Bernsmeier Christine, Weisskopf Diego M, Pflueger Marlon O, Mosimann Jan, Campana Benedetta, Terracciano Luigi, Beglinger Christoph, Heim Markus H, Cajochen Christian
High-volume plasma exchange in patients with acute liver failure: An open randomised controlled trial
Larsen F, Antoniades C, Hansen B, Frederiksen H, Hockerstedt K, Clemmesen J, Bjerring P, Eefsen M, Shawcross D, Auzinger G, Bernal W, Triantafyllou E, Patel V, Isoniemi H, Rasmussen A, Bernsmeier C, Schmidt L, Wendon J. High-volume plasma exchange in patients with acute liver failure: An open randomised controlled trial. J Hepatol 2015; 64:69-78.
29.08.2015High-volume plasma exchange in patients with acute liver failure: An open randomised controlled trial
29.08.2015J Hepatol 2015; 64:69-78
Larsen Fin Stolze, Antoniades Charalambos G, Hansen Bent Adel, Frederiksen Hans-Jørgen, Hockerstedt Krister, Clemmesen Jens Otto, Bjerring Peter Nissen, Eefsen Martin, Shawcross Debbie, Auzinger Georg, Bernal William, Triantafyllou Evangelos, Patel Vishal C, Isoniemi Helena, Rasmussen Allan, Bernsmeier Christine, Schmidt Lars Ebbe, Wendon Julia
Immunotherapy in the treatment and prevention of infection in acute-on-chronic liver failure
Bernsmeier C, Singanayagam A, Patel V, Wendon J, Antoniades C. Immunotherapy in the treatment and prevention of infection in acute-on-chronic liver failure. Immunotherapy 2015; 7:641-54.
12.06.2015Immunotherapy in the treatment and prevention of infection in acute-on-chronic liver failure
12.06.2015Immunotherapy 2015; 7:641-54
Bernsmeier Christine, Singanayagam Arjuna, Patel Vishal C, Wendon Julia, Antoniades Charalambos G
Patients With Acute-on-Chronic Liver Failure Have Increased Numbers of Regulatory Immune Cells Expressing the Receptor Tyrosine Kinase MERTK
Bernsmeier C, Heneghan M, Ma Y, Jassem W, Heaton N, Adams D, Quaglia A, Thursz M, Wendon J, Auzinger G, Bernal W, Khamri W, Pop O, Singanayagam A, Triantafyllou E, Patel V, Weston C, Curbishley S, Sadiq F, Vergis N, Antoniades C. Patients With Acute-on-Chronic Liver Failure Have Increased Numbers of Regulatory Immune Cells Expressing the Receptor Tyrosine Kinase MERTK. Gastroenterology 2014; 148:603-615.e14.
03.12.2014Patients With Acute-on-Chronic Liver Failure Have Increased Numbers of Regulatory Immune Cells Expressing the Receptor Tyrosine Kinase MERTK
03.12.2014Gastroenterology 2014; 148:603-615.e14
Bernsmeier Christine, Heneghan Michael, Ma Yun, Jassem Wayel, Heaton Nigel D, Adams David H, Quaglia Alberto, Thursz Mark R, Wendon Julia, Auzinger Georg, Bernal William, Khamri Wafa, Pop Oltin T, Singanayagam Arjuna, Triantafyllou Evangelos, Patel Vishal C, Weston Christopher J, Curbishley Stuart, Sadiq Fouzia, Vergis Nikhil, Antoniades Charalambos G
What's new in acute liver failure?
Bernsmeier C, Antoniades C, Wendon J. What's new in acute liver failure?. Intensive Care Med 2014; 40:1545-8.
01.07.2014What's new in acute liver failure?
01.07.2014Intensive Care Med 2014; 40:1545-8
Bernsmeier Christine, Antoniades Charalambos G, Wendon Julia
The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota
Balmer M, McCoy K, Heim M, Dickgreber N, Stroka D, Wyss M, Ronchi F, Bernsmeier C, Patuto N, Fahrner R, Van Vlierberghe H, Grieco A, Miele L, Hapfelmeier S, Lawson M, De Gottardi A, Slack E, Macpherson A. The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota. Sci Transl Med 2014; 6:237ra66.
21.05.2014The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota
21.05.2014Sci Transl Med 2014; 6:237ra66
Balmer Maria L, McCoy Kathy D, Heim Markus H, Dickgreber Nina, Stroka Deborah, Wyss Madeleine, Ronchi Francesca, Bernsmeier Christine, Patuto Nicola, Fahrner René, Van Vlierberghe Hans, Grieco Antonio, Miele Luca, Hapfelmeier Siegfried, Lawson Melissa A E, De Gottardi Andrea, Slack Emma, Macpherson Andrew J
Secretory leukocyte protease inhibitor: a pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure
Antoniades C, Heneghan M, Heaton N, Jassem W, Bernal W, Vergani D, Ma Y, Quaglia A, Wendon J, Goldin R, Gilroy D, Khamri W, Abeles R, Taams L, Triantafyllou E, Possamai L, Bernsmeier C, Mitry R, O'Brien A, Thursz M. Secretory leukocyte protease inhibitor: a pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure. Hepatology 2014; 59:1564-76.
28.02.2014Secretory leukocyte protease inhibitor: a pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure
28.02.2014Hepatology 2014; 59:1564-76
Antoniades Charalambos Gustav, Heneghan Michael, Heaton Nigel, Jassem Wayel, Bernal William, Vergani Diego, Ma Yun, Quaglia Alberto, Wendon Julia, Goldin Robert, Gilroy Derek, Khamri Wafa, Abeles Robin D, Taams Leonie S, Triantafyllou Evangelos, Possamai Lucia A, Bernsmeier Christine, Mitry Ragai R, O'Brien Alistair, Thursz Mark
Glucose-induced glucagon-like Peptide 1 secretion is deficient in patients with non-alcoholic fatty liver disease
Bernsmeier C, Meyer-Gerspach A, Blaser L, Jeker L, Steinert R, Heim M, Beglinger C. Glucose-induced glucagon-like Peptide 1 secretion is deficient in patients with non-alcoholic fatty liver disease. PloS one 2014; 9:e87488.
29.01.2014Glucose-induced glucagon-like Peptide 1 secretion is deficient in patients with non-alcoholic fatty liver disease
29.01.2014PloS one 2014; 9:e87488
Bernsmeier Christine, Meyer-Gerspach Anne C, Blaser Lea S, Jeker Lia, Steinert Robert E, Heim Markus H, Beglinger Christoph