Lorenz Trümper
A modular transcriptome map of mature B cell lymphomas
Loeffler-Wirth H, Pott C, Schwaenen C, Trautmann H, Wessendorf S, Stein H, Szczepanowski M, Trümper L, Hummel M, Klapper W, Siebert R, Loeffler M, Binder H, Rosenwald A, Ott G, Kreuz M, Hopp L, Arakelyan A, Haake A, Cogliatti S, Feller A, Hansmann M, Lenze D, Möller P, Müller-Hermelink H, Fortenbacher E, Willscher E, German Cancer Aid consortium Molecular Mechanisms for Malignant Lymphoma. A modular transcriptome map of mature B cell lymphomas. Genome Med 2019; 11:27.
30.04.2019A modular transcriptome map of mature B cell lymphomas
30.04.2019Genome Med 2019; 11:27
Loeffler-Wirth Henry, Pott Christiane, Schwaenen Carsten, Trautmann Heiko, Wessendorf Swen, Stein Harald, Szczepanowski Monika, Trümper Lorenz, Hummel Michael, Klapper Wolfram, Siebert Reiner, Loeffler Markus, Binder Hans, Rosenwald Andreas, Ott German, Kreuz Markus, Hopp Lydia, Arakelyan Arsen, Haake Andrea, Cogliatti Sergio B., Feller Alfred C, Hansmann Martin-Leo, Lenze Dido, Möller Peter, Müller-Hermelink Hans Konrad, Fortenbacher Erik, Willscher Edith, German Cancer Aid consortium Molecular Mechanisms for Malignant Lymphoma
Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC
Paul U, Stein H, Hansmann M, Möller P, Szczepanowski M, Burkhardt B, Pfreundschuh M, Schmitz N, Loeffler M, Trümper L, Siebert R, Cogliatti S, Feller A, Rosenwald A, Richter J, Stuhlmann-Laiesz C, Kreuz M, Nagel I, Horn H, Staiger A, Aukema S, Hummel M, Ott G, Spang R, Klapper W. Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC. Leuk Lymphoma 2017:1-9.
25.08.2017Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC
25.08.2017Leuk Lymphoma 2017:1-9
Paul Ulrike, Stein Harald, Hansmann Martin-Leo, Möller Peter, Szczepanowski Monika, Burkhardt Birgit, Pfreundschuh Michael, Schmitz Norbert, Loeffler Markus, Trümper Lorenz, Siebert Reiner, Cogliatti Sergio B., Feller Alfred C, Rosenwald Andreas, Richter Julia, Stuhlmann-Laiesz Christiane, Kreuz Markus, Nagel Inga, Horn Heike, Staiger Annette M, Aukema Sietse M, Hummel Michael, Ott German, Spang Rainer, Klapper Wolfram
Clinical Impact of the Cell-of-Origin Classification and the MYC/ BCL2 Dual Expresser Status in Diffuse Large B-Cell Lymphoma Treated Within Prospective Clinical Trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group
Staiger A, Hartmann S, Möller P, Cogliatti S, Lenz G, Trümper L, Löffler M, Schmitz N, Pfreundschuh M, Rosenwald A, Ott G, Hansmann M, Lenze D, Ziepert M, Horn H, Scott D, Barth T, Bernd H, Feller A, Klapper W, Szczepanowski M, Hummel M, Stein H, German High-Grade Lymphoma Study Group. Clinical Impact of the Cell-of-Origin Classification and the MYC/ BCL2 Dual Expresser Status in Diffuse Large B-Cell Lymphoma Treated Within Prospective Clinical Trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group. J Clin Oncol 2017; 35:2515-2526.
19.05.2017Clinical Impact of the Cell-of-Origin Classification and the MYC/ BCL2 Dual Expresser Status in Diffuse Large B-Cell Lymphoma Treated Within Prospective Clinical Trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group
19.05.2017J Clin Oncol 2017; 35:2515-2526
Staiger Annette M, Hartmann Sylvia, Möller Peter, Cogliatti Sergio B., Lenz Georg, Trümper Lorenz, Löffler Markus, Schmitz Norbert, Pfreundschuh Michael, Rosenwald Andreas, Ott German, Hansmann Martin-Leo, Lenze Dido, Ziepert Marita, Horn Heike, Scott David W, Barth Thomas F E, Bernd Heinz-Wolfram, Feller Alfred C, Klapper Wolfram, Szczepanowski Monika, Hummel Michael, Stein Harald, German High-Grade Lymphoma Study Group
The PCBP1 gene encoding poly(rC) binding protein I is recurrently mutated in Burkitt lymphoma
Wagener R, Betts M, Russell R, Bernhart S, Hoffmann S, Rosenstiel P, Schilhabel M, Szczepanowski M, Trümper L, Klapper W, Siebert R, ICGC MMML-Seq-Project, Rohde M, Richter J, Möller P, Aukema S, Schlesner M, Haake A, Burkhardt B, Claviez A, Drexler H, Hummel M, Kreuz M, Loeffler M, Rosolowski M, López C, "Molecular Mechanisms in Malignant Lymphomas" Network Project of the Deutsche Krebshilfe. The PCBP1 gene encoding poly(rC) binding protein I is recurrently mutated in Burkitt lymphoma. Genes, chromosomes & cancer 2015; 54:555-64.
14.07.2015The PCBP1 gene encoding poly(rC) binding protein I is recurrently mutated in Burkitt lymphoma
14.07.2015Genes, chromosomes & cancer 2015; 54:555-64
Wagener Rabea, Betts Matthew J, Russell Robert B, Bernhart Stephan H, Hoffmann Steve, Rosenstiel Philip, Schilhabel Markus, Szczepanowski Monika, Trümper Lorenz, Klapper Wolfram, Siebert Reiner, ICGC MMML-Seq-Project, Rohde Marius, Richter Julia, Möller Peter, Aukema Sietse M, Schlesner Matthias, Haake Andrea, Burkhardt Birgit, Claviez Alexander, Drexler Hans G, Hummel Michael, Kreuz Markus, Loeffler Markus, Rosolowski Maciej, López Cristina, "Molecular Mechanisms in Malignant Lymphomas" Network Project of the Deutsche Krebshilfe
A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma
Salaverria I, Oschlies I, Rosolowski M, Russell R, Rymkiewicz G, Schindler D, Schlesner M, Scholtysik R, Schwaenen C, Spang R, Szczepanowski M, Trümper L, Vater I, Wessendorf S, Klapper W, Siebert R, Molecular Mechanisms in Malignant Lymphoma Network Project, Nagel I, Macleod R, Löffler M, Martin-Guerrero I, Wagener R, Kreuz M, Kohler C, Richter J, Pienkowska-Grela B, Adam P, Burkhardt B, Claviez A, Damm-Welk C, Drexler H, Hummel M, Jaffe E, Küppers R, Lefebvre C, Lisfeld J, Berlin-Frankfurt-Münster Non-Hodgkin Lymphoma Group. A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma. Blood 2014; 123:1187-98.
07.01.2014A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma
07.01.2014Blood 2014; 123:1187-98
Salaverria Itziar, Oschlies Ilske, Rosolowski Maciej, Russell Robert B, Rymkiewicz Grzegorz, Schindler Detlev, Schlesner Matthias, Scholtysik René, Schwaenen Carsten, Spang Rainer, Szczepanowski Monika, Trümper Lorenz, Vater Inga, Wessendorf Swen, Klapper Wolfram, Siebert Reiner, Molecular Mechanisms in Malignant Lymphoma Network Project, Nagel Inga, Macleod Roderick A F, Löffler Markus, Martin-Guerrero Idoia, Wagener Rabea, Kreuz Markus, Kohler Christian W, Richter Julia, Pienkowska-Grela Barbara, Adam Patrick, Burkhardt Birgit, Claviez Alexander, Damm-Welk Christine, Drexler Hans G, Hummel Michael, Jaffe Elaine S, Küppers Ralf, Lefebvre Christine, Lisfeld Jasmin, Berlin-Frankfurt-Münster Non-Hodgkin Lymphoma Group
Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma
Aukema S, Stein H, Trautmann H, Wessendorf S, Trümper L, Loeffler M, Spang R, Kluin P, Klapper W, Siebert R, Molecular Mechanisms in Malignant Lymphomas Network Project, Schwaenen C, Szczepanowski M, Rosenwald A, Kreuz M, Kohler C, Rosolowski M, Hasenclever D, Hummel M, Küppers R, Lenze D, Ott G, Pott C, Richter J, Cogliatti S. Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma. Haematologica 2013; 99:726-35.
31.10.2013Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma
31.10.2013Haematologica 2013; 99:726-35
Aukema Sietse M, Stein Harald, Trautmann Heiko, Wessendorf Swen, Trümper Lorenz, Loeffler Markus, Spang Rainer, Kluin Philip M, Klapper Wolfram, Siebert Reiner, Molecular Mechanisms in Malignant Lymphomas Network Project, Schwaenen Carsten, Szczepanowski Monika, Rosenwald Andreas, Kreuz Markus, Kohler Christian W, Rosolowski Maciej, Hasenclever Dirk, Hummel Michael, Küppers Ralf, Lenze Dido, Ott German, Pott Christiane, Richter Julia, Cogliatti Sergio B.
MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma
Horn H, Cogliatti S, Pfreundschuh M, Schmitz N, Trümper L, Siebert R, Loeffler M, Rosenwald A, Ott G, Möller P, Schmelter C, Hansmann M, Ziepert M, Becher C, Barth T, Bernd H, Feller A, Klapper W, Hummel M, Stein H, German High-Grade Non-Hodgkin Lymphoma Study Group. MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma. Blood 2013; 121:2253-63.
18.01.2013MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma
18.01.2013Blood 2013; 121:2253-63
Horn Heike, Cogliatti Sergio B., Pfreundschuh Michael, Schmitz Norbert, Trümper Lorenz, Siebert Reiner, Loeffler Markus, Rosenwald Andreas, Ott German, Möller Peter, Schmelter Christopher, Hansmann Martin-Leo, Ziepert Marita, Becher Claudia, Barth Thomas F E, Bernd Heinz-Wolfram, Feller Alfred C, Klapper Wolfram, Hummel Michael, Stein Harald, German High-Grade Non-Hodgkin Lymphoma Study Group
Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL
Ott G, Frank M, Hansmann M, Barth T, Möller P, Cogliatti S, Pfreundschuh M, Schmitz N, Trümper L, Loeffler M, Müller-Hermelink H, Stein H, Ziepert M, Klapper W, Horn H, Szczepanowski M, Bernd H, Thorns C, Feller A, Lenze D, Hummel M, Rosenwald A. Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL. Blood 2010; 116:4916-25.
24.08.2010Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL
24.08.2010Blood 2010; 116:4916-25
Ott German, Frank Matthias, Hansmann Martin-Leo, Barth Thomas F E, Möller Peter, Cogliatti Sergio B., Pfreundschuh Michael, Schmitz Norbert, Trümper Lorenz, Loeffler Markus, Müller-Hermelink Hans-Konrad, Stein Harald, Ziepert Marita, Klapper Wolfram, Horn Heike, Szczepanowski Monika, Bernd Heinz-Wolfram, Thorns Christoph, Feller Alfred C, Lenze Dido, Hummel Michael, Rosenwald Andreas
Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma - analyses of cases from two prospective randomized clinical trials
Bernd H, Möller P, Cogliatti S, Pfreundschuh M, Schmitz N, Trümper L, Höller S, Löffler M, Feller A, Barth T, Müller-Hermelink H, Rosenwald A, Ziepert M, Thorns C, Klapper W, Wacker H, Hummel M, Stein H, Hansmann M, Ott G, German High Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL). Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma - analyses of cases from two prospective randomized clinical trials. Haematologica 2009; 94:1569-80.
01.11.2009Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma - analyses of cases from two prospective randomized clinical trials
01.11.2009Haematologica 2009; 94:1569-80
Bernd Heinz-Wolfram, Möller Peter, Cogliatti Sergio B., Pfreundschuh Michael, Schmitz Norbert, Trümper Lorenz, Höller Silvia, Löffler Markus, Feller Alfred C, Barth Thomas F E, Müller-Hermelink Hans-Konrad, Rosenwald Andreas, Ziepert Marita, Thorns Christoph, Klapper Wolfram, Wacker Hans-Heinrich, Hummel Michael, Stein Harald, Hansmann Martin-Leo, Ott German, German High Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL)
New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling
Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe, Seifert M, Schübeler D, Schwaenen C, Rosenwald A, Prosper F, Pott C, Ott G, Möller P, Macleod R, Stürzenhofecker B, Weber M, Siebert R, Hasenclever D, Barker D, Esteller M, Spang R, Stein H, Trümper L, Loeffler M, Wessendorf S, Küppers R, Korn B, Ballestar E, Lopez-Serra L, Richter J, Rosolowski M, Wickham-Garcia E, Ammerpohl O, Bentink S, Bibikova M, Kreuz M, Berger H, Agirre X, Klapper W, Hummel M, Hansmann M, Fraga M, Fan J, Drexler H, Cogliatti S, Calvanese V, Bernd H, Martín-Subero J. New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling. Blood 2009; 113:2488-97.
12.03.2009New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling
12.03.2009Blood 2009; 113:2488-97
Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe, Seifert Marc, Schübeler Dirk, Schwaenen Carsten, Rosenwald Andreas, Prosper Felipe, Pott Christiane, Ott German, Möller Peter, Macleod Roderick A F, Stürzenhofecker Benjamin, Weber Michael, Siebert Reiner, Hasenclever Dirk, Barker David, Esteller Manel, Spang Rainer, Stein Harald, Trümper Lorenz, Loeffler Markus, Wessendorf Swen, Küppers Ralf, Korn Bernhard, Ballestar Esteban, Lopez-Serra Lidia, Richter Julia, Rosolowski Maciej, Wickham-Garcia Eliza, Ammerpohl Ole, Bentink Stefan, Bibikova Marina, Kreuz Markus, Berger Hilmar, Agirre Xabier, Klapper Wolfram, Hummel Michael, Hansmann Martin L, Fraga Mario F, Fan Jian-Bing, Drexler Hans G, Cogliatti Sergio B., Calvanese Vincenzo, Bernd Heinz-Wolfram, Martín-Subero José I
Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma
Dierlamm J, Cogliatti S, Möller P, Schwaenen C, Stein H, Löffler M, Spang R, Trümper L, Siebert R, Ott G, Haralambieva E, Murga Penas E, Bentink S, Wessendorf S, Berger H, Hummel M, Klapper W, Lenze D, Rosenwald A, Deutsche Krebshilfe Network Project "Molecular Mechanisms in Malignant Lymphomas". Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma. Haematologica 2008; 93:688-96.
01.05.2008Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma
01.05.2008Haematologica 2008; 93:688-96
Dierlamm Judith, Cogliatti Sergio B., Möller Peter, Schwaenen Carsten, Stein Harald, Löffler Markus, Spang Rainer, Trümper Lorenz, Siebert Reiner, Ott German, Haralambieva Eugenia, Murga Penas Eva M, Bentink Stefan, Wessendorf Swen, Berger Hilmar, Hummel Michael, Klapper Wolfram, Lenze Dido, Rosenwald Andreas, Deutsche Krebshilfe Network Project "Molecular Mechanisms in Malignant Lymphomas"