Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
Akhlaghpour M, Haritunians T, More S, Thomas L, Stamps D, Dube S, Li D, Yang S, Landers C, Mengesha E, Hamade H, Murali R, Potdar A, Wolf A, Botwin G, Khrom M, International IBD Genetics Consortium, Ananthakrishnan A, Faubion W, Jabri B, Lira S, Newberry R, Sandler R, Sartor R, Xavier R, Brant S, Cho J, Duerr R, Lazarev M, Rioux J, Schumm L, Silverberg M, Zaghiyan K, Fleshner P, Melmed G, Vasiliauskas E, Ha C, Rabizadeh S, Syal G, Bonthala N, Ziring D, Targan S, Long M, McGovern D, Michelsen K, Brand S. Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. Gut 2023; 72:2068-2080.
20.04.2023
Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
20.04.2023
Gut 2023; 72:2068-2080
Akhlaghpour Marzieh, Haritunians Talin, More Shyam K, Thomas Lisa S, Stamps Dalton T, Dube Shishir, Li Dalin, Yang Shaohong, Landers Carol J, Mengesha Emebet, Hamade Hussein, Murali Ramachandran, Potdar Alka A, Wolf Andrea J, Botwin Gregory J, Khrom Michelle, International IBD Genetics Consortium, Ananthakrishnan Ashwin N, Faubion William A, Jabri Bana, Lira Sergio A, Newberry Rodney D, Sandler Robert S, Sartor R Balfour, Xavier Ramnik J, Brant Steven R, Cho Judy H, Duerr Richard H, Lazarev Mark G, Rioux John D, Schumm L Philip, Silverberg Mark S, Zaghiyan Karen, Fleshner Phillip, Melmed Gil Y, Vasiliauskas Eric A, Ha Christina, Rabizadeh Shervin, Syal Gaurav, Bonthala Nirupama N, Ziring David A, Targan Stephan R, Long Millie, McGovern Dermot P B, Michelsen Kathrin S, Brand Stephan
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