Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3

Nihei Y, Edbauer D, Nuscher B, Kamp F, Bavarian Brain Banking Alliance, German Consortium for Frontotemporal Lobar Degeneration, Weber M, Sommacal A, Hermann A, Japtok J, Khosravi B, Zhou Q, Arzberger T, Werner G, Mori K, Haass C. Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3. Acta Neuropathol 2019; 139:99-118.