Dr. Mario Novkovic
Communication, construction, and fluid control: lymphoid organ fibroblastic reticular cell and conduit networks
Acton S, Onder L, Novkovic M, Martinez V, Ludewig B. Communication, construction, and fluid control: lymphoid organ fibroblastic reticular cell and conduit networks. Trends Immunol 2021; 42:782-794.
03.08.2021Communication, construction, and fluid control: lymphoid organ fibroblastic reticular cell and conduit networks
03.08.2021Trends Immunol 2021; 42:782-794
Acton Sophie E, Onder Lucas, Novkovic Mario, Martinez Victor G, Ludewig Burkhard
Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells
Pérez Shibayama C, Gil Cruz C, Colston J, Novkovic M, De Martin A, Ring S, Onder L, Cheng H, Lütge M, Islander U, Ludewig B. Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells. Sci Immunol 2020; 5
11.09.2020Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells
11.09.2020Sci Immunol 2020; 5
Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Colston Julia, Novkovic Mario, De Martin Angelina, Ring Sandra, Onder Lucas, Cheng Hung-Wei, Lütge Mechthild, Islander Ulrika, Ludewig Burkhard
B cell zone reticular cell microenvironments shape CXCL13 gradient formation
Cosgrove J, Uguccioni M, Legler D, Lacey C, Coatesworth A, Polak W, Cupedo T, Manoury B, Thelen M, Stein J, Wolf M, Leake M, Timmis J, Ludewig B, Heller M, Venetz D, Taylor E, Novkovic M, Albrecht S, Pikor N, Zhou Z, Onder L, Mörbe U, Cupovic J, Miller H, Alden K, Thuery A, O'Toole P, Pinter R, Jarrett S, Coles M. B cell zone reticular cell microenvironments shape CXCL13 gradient formation. Nat Commun 2020; 11:3677.
22.07.2020B cell zone reticular cell microenvironments shape CXCL13 gradient formation
22.07.2020Nat Commun 2020; 11:3677
Cosgrove Jason, Uguccioni Mariagrazia, Legler Daniel F, Lacey Charles J, Coatesworth Andrew, Polak Wojciech G, Cupedo Tom, Manoury Bénedicte, Thelen Marcus, Stein Jens V, Wolf Marlene, Leake Mark C, Timmis Jon, Ludewig Burkhard, Heller Manfred, Venetz Daniel, Taylor Emily, Novkovic Mario, Albrecht Stefan, Pikor Natalia, Zhou Zhaoukun, Onder Lucas, Mörbe Urs, Cupovic Jovana, Miller Helen, Alden Kieran, Thuery Anne, O'Toole Peter, Pinter Rita, Jarrett Simon, Coles Mark C
Remodeling of light and dark zone follicular dendritic cells governs germinal center responses
Pikor N, Onder L, Linterman M, Nagasawa T, Nombela-Arrieta C, Cheng H, Novkovic M, Pérez Shibayama C, Gil Cruz C, Lütge M, Mörbe U, Ludewig B. Remodeling of light and dark zone follicular dendritic cells governs germinal center responses. Nat Immunol 2020; 21:649-659.
18.05.2020Remodeling of light and dark zone follicular dendritic cells governs germinal center responses
18.05.2020Nat Immunol 2020; 21:649-659
Pikor Natalia, Onder Lucas, Linterman Michelle A, Nagasawa Takashi, Nombela-Arrieta César, Cheng Hung-Wei, Novkovic Mario, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Lütge Mechthild, Mörbe Urs, Ludewig Burkhard
Topological Structure and Robustness of the Lymph Node Conduit System
Novkovic M, Onder L, Bocharov G, Ludewig B. Topological Structure and Robustness of the Lymph Node Conduit System. Cell Rep 2020; 30:893-904.e6.
21.01.2020Topological Structure and Robustness of the Lymph Node Conduit System
21.01.2020Cell Rep 2020; 30:893-904.e6
Novkovic Mario, Onder Lucas, Bocharov Gennady, Ludewig Burkhard
Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy
Gil Cruz C, Jahns R, Wyss M, Mooser C, Lambrecht B, Maeder M, Rickli H, Flatz L, Eriksson U, Geuking M, McCoy K, Boivin-Jahns V, Slack E, Arnoldini M, Pérez Shibayama C, De Martin A, Ronchi F, Van der Borght K, Niederer R, Onder L, Lütge M, Novkovic M, Nindl V, Ramos G, Ludewig B. Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy. Science 2019; 366:881-886.
15.11.2019Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy
15.11.2019Science 2019; 366:881-886
Gil Cruz Cristina, Jahns Roland, Wyss Madeleine, Mooser Catherine, Lambrecht Bart N, Maeder Micha, Rickli Hans, Flatz Lukas, Eriksson Urs, Geuking Markus B, McCoy Kathy D, Boivin-Jahns Valérie, Slack Emma M C, Arnoldini Markus, Pérez Shibayama Christian Ivan, De Martin Angelina, Ronchi Francesca, Van der Borght Katrien, Niederer Rebekka, Onder Lucas, Lütge Mechthild, Novkovic Mario, Nindl Veronika, Ramos Gustavo, Ludewig Burkhard
Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
Cheng H, Hehlgans T, Rülicke T, Pfeffer K, Sorg U, Tersteegen A, Miyazaki J, Robinson M, Scandella E, Pikor N, Lütge M, Soneson C, Novkovic M, Onder L, Ludewig B. Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp. Nat Commun 2019; 10:1739.
15.04.2019Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
15.04.2019Nat Commun 2019; 10:1739
Cheng Hung-Wei, Hehlgans Thomas, Rülicke Thomas, Pfeffer Klaus, Sorg Ursula, Tersteegen Anne, Miyazaki Jun-Ichi, Robinson Mark D, Scandella Elke, Pikor Natalia, Lütge Mechthild, Soneson Charlotte, Novkovic Mario, Onder Lucas, Ludewig Burkhard
Integrative Computational Modeling of the Lymph Node Stromal Cell Landscape
Novkovic M, Onder L, Cheng H, Bocharov G, Ludewig B. Integrative Computational Modeling of the Lymph Node Stromal Cell Landscape. Front Immunol 2018; 9:2428.
23.10.2018Integrative Computational Modeling of the Lymph Node Stromal Cell Landscape
23.10.2018Front Immunol 2018; 9:2428
Novkovic Mario, Onder Lucas, Cheng Hung-Wei, Bocharov Gennady, Ludewig Burkhard
Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity
Pérez Shibayama C, Gommerman J, Scandella E, Robinson M, Soneson C, Mack M, Turley S, Buechler M, López-Macías C, Li C, Novkovic M, Mörbe U, Printz A, Onder L, Cheng H, Gil Cruz C, Ludewig B. Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity. Sci Immunol 2018; 3
10.08.2018Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity
10.08.2018Sci Immunol 2018; 3
Pérez Shibayama Christian Ivan, Gommerman Jennifer, Scandella Elke, Robinson Mark D, Soneson Charlotte, Mack Matthias, Turley Shannon J, Buechler Matthew B, López-Macías Constantino, Li Conglei, Novkovic Mario, Mörbe Urs, Printz Andrea, Onder Lucas, Cheng Hung-Wei, Gil Cruz Cristina, Ludewig Burkhard
CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
Cheng H, Brutsche M, Jochum W, Schneider T, Rodriguez R, Tarantino I, Pikor N, Novkovic M, Bösch M, Cupovic J, Onder L, Ludewig B. CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses. J Allergy Clin Immunol 2018
31.01.2018CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
31.01.2018J Allergy Clin Immunol 2018
Cheng Hung-Wei, Brutsche Martin, Jochum Wolfram, Schneider Tino, Rodriguez Regulo, Tarantino Ignazio, Pikor Natalia, Novkovic Mario, Bösch Maximilian, Cupovic Jovana, Onder Lucas, Ludewig Burkhard
Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness
Bösch M, Knauer M, Ruhstaller T, Jochum W, Gastl G, Sopper S, Mörbe U, Novkovic M, Cheng H, Onder L, Ludewig B. Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness. Oncoimmunology 2018; 7:e1414129.
03.01.2018Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness
03.01.2018Oncoimmunology 2018; 7:e1414129
Bösch Maximilian, Knauer Michael, Ruhstaller Thomas, Jochum Wolfram, Gastl Guenther, Sopper Sieghart, Mörbe Urs, Novkovic Mario, Cheng Hung-Wei, Onder Lucas, Ludewig Burkhard
Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis
Onder L, Scandella E, Sawa S, Mueller C, Gommerman J, Rülicke T, Waisman A, Becher B, Pfeffer K, Hehlgans T, Cheng H, Novkovic M, Pikor N, Mörbe U, Ludewig B. Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis. Immunity 2017; 47:80-92.e4.
11.07.2017Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis
11.07.2017Immunity 2017; 47:80-92.e4
Onder Lucas, Scandella Elke, Sawa Shinichiro, Mueller Christopher G, Gommerman Jennifer, Rülicke Thomas, Waisman Ari, Becher Burkhard, Pfeffer Klaus, Hehlgans Thomas, Cheng Hung-Wei, Novkovic Mario, Pikor Natalia, Mörbe Urs, Ludewig Burkhard
Graph Theory-Based Analysis of the Lymph Node Fibroblastic Reticular Cell Network
Novkovic M, Onder L, Bocharov G, Ludewig B. Graph Theory-Based Analysis of the Lymph Node Fibroblastic Reticular Cell Network. Methods Mol Biol 2017; 1591:43-57.
01.01.2017Graph Theory-Based Analysis of the Lymph Node Fibroblastic Reticular Cell Network
01.01.2017Methods Mol Biol 2017; 1591:43-57
Novkovic Mario, Onder Lucas, Bocharov Gennady, Ludewig Burkhard
Critical Issues in Modelling Lymph Node Physiology
Grebennikov D, van Loon R, Novkovic M, Onder L, Savinkov R, Sazonov I, Tretyakova R, J Watson D, Bocharov G. Critical Issues in Modelling Lymph Node Physiology. Computation 2016; 5:3.
24.12.2016Critical Issues in Modelling Lymph Node Physiology
24.12.2016Computation 2016; 5:3
Grebennikov Dmitry, van Loon Raoul, Novkovic Mario, Onder Lucas, Savinkov Rostislav, Sazonov Igor, Tretyakova Rufina, J Watson Daniel, Bocharov Gennady
Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs
Gil Cruz C, Scandella E, Ikuta K, Cui G, Abe S, McCoy K, Geuking M, Lang P, Novkovic M, Cheng H, Cupovic J, Chai Q, Onder L, Pérez Shibayama C, Ludewig B. Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs. Nat Immunol 2016; 17:1388-1396.
31.10.2016Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs
31.10.2016Nat Immunol 2016; 17:1388-1396
Gil Cruz Cristina, Scandella Elke, Ikuta Koichi, Cui Guangwei, Abe Shinya, McCoy Kathy D, Geuking Markus B, Lang Philipp A, Novkovic Mario, Cheng Hung-Wei, Cupovic Jovana, Chai Qian, Onder Lucas, Pérez Shibayama Christian Ivan, Ludewig Burkhard
Data-driven modelling of the FRC network for studying the fluid flow in the conduit system
Savinkov R, Kislitsyn A, Watson D, van Loon R, Sazonov I, Novkovic M, Onder L, Bocharov G. Data-driven modelling of the FRC network for studying the fluid flow in the conduit system. Engineering Applications of Artificial Intelligence 2016; 62:341-349.
28.10.2016Data-driven modelling of the FRC network for studying the fluid flow in the conduit system
28.10.2016Engineering Applications of Artificial Intelligence 2016; 62:341-349
Savinkov Rostislav, Kislitsyn Alexey, Watson Daniel J., van Loon Raoul, Sazonov Igor, Novkovic Mario, Onder Lucas, Bocharov Gennady
Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
Novkovic M, Turley S, Bocharov G, Stein J, Scandella E, Cremasco V, Bomze D, Abe J, Cupovic J, Onder L, Ludewig B. Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality. PLoS Biol 2016; 14:e1002515.
14.07.2016Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
14.07.2016PLoS Biol 2016; 14:e1002515
Novkovic Mario, Turley Shannon J, Bocharov Gennady, Stein Jens V, Scandella Elke, Cremasco Viviana, Bomze David, Abe Jun, Cupovic Jovana, Onder Lucas, Ludewig Burkhard
Computational Approach to 3D Modeling of the Lymph Node Geometry
Kislitsyn A, Savinkov R, Novkovic M, Onder L, Bocharov G. Computational Approach to 3D Modeling of the Lymph Node Geometry. Computation 2015; 3:222-234.
22.05.2015Computational Approach to 3D Modeling of the Lymph Node Geometry
22.05.2015Computation 2015; 3:222-234
Kislitsyn Alexey, Savinkov Rostislav, Novkovic Mario, Onder Lucas, Bocharov Gennady
Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction
Onder L, Waisman A, Becher B, Ledermann B, Mair F, Maier R, Bomze D, Novkovic M, Caviezel-Firner S, Cheng H, Chai Q, Scandella E, Nindl V, Ludewig B. Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction. Eur J Immunol 2015
14.05.2015Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction
14.05.2015Eur J Immunol 2015
Onder Lucas, Waisman Ari, Becher Burkhard, Ledermann Birgit, Mair Florian, Maier Reinhard, Bomze David, Novkovic Mario, Caviezel-Firner Sonja, Cheng Hung-Wei, Chai Qian, Scandella Elke, Nindl Veronika, Ludewig Burkhard
Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences
Ilić N, Novkovic M, Guida F, Xhindoli D, Benincasa M, Tossi A, Juretić D. Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences. Biochim Biophys Acta 2012; 1828:1004-1012.
27.11.2012Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences
27.11.2012Biochim Biophys Acta 2012; 1828:1004-1012
Ilić Nada, Novkovic Mario, Guida Filomena, Xhindoli Daniela, Benincasa Monica, Tossi Alessandro, Juretić Davor