International IBD Genetics Consortium
Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
Akhlaghpour M, Haritunians T, More S, Thomas L, Stamps D, Dube S, Li D, Yang S, Landers C, Mengesha E, Hamade H, Murali R, Potdar A, Wolf A, Botwin G, Khrom M, International IBD Genetics Consortium, Ananthakrishnan A, Faubion W, Jabri B, Lira S, Newberry R, Sandler R, Sartor R, Xavier R, Brant S, Cho J, Duerr R, Lazarev M, Rioux J, Schumm L, Silverberg M, Zaghiyan K, Fleshner P, Melmed G, Vasiliauskas E, Ha C, Rabizadeh S, Syal G, Bonthala N, Ziring D, Targan S, Long M, McGovern D, Michelsen K, Brand S. Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. Gut 2023; 72:2068-2080.
20.04.2023Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
20.04.2023Gut 2023; 72:2068-2080
Akhlaghpour Marzieh, Haritunians Talin, More Shyam K, Thomas Lisa S, Stamps Dalton T, Dube Shishir, Li Dalin, Yang Shaohong, Landers Carol J, Mengesha Emebet, Hamade Hussein, Murali Ramachandran, Potdar Alka A, Wolf Andrea J, Botwin Gregory J, Khrom Michelle, International IBD Genetics Consortium, Ananthakrishnan Ashwin N, Faubion William A, Jabri Bana, Lira Sergio A, Newberry Rodney D, Sandler Robert S, Sartor R Balfour, Xavier Ramnik J, Brant Steven R, Cho Judy H, Duerr Richard H, Lazarev Mark G, Rioux John D, Schumm L Philip, Silverberg Mark S, Zaghiyan Karen, Fleshner Phillip, Melmed Gil Y, Vasiliauskas Eric A, Ha Christina, Rabizadeh Shervin, Syal Gaurav, Bonthala Nirupama N, Ziring David A, Targan Stephan R, Long Millie, McGovern Dermot P B, Michelsen Kathrin S, Brand Stephan
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
Momozawa Y, Hoentjen F, Löwenberg M, Oldenburg B, Pierik M, Vander Meulen-de Jong A, Janneke van der Woude C, Visschedijk M, International IBD Genetics Consortium, Lathrop M, Hugot J, Weersma R, De Vos M, Franchimont D, Vermeire S, Kubo M, Louis E, Bouma G, Amininejad L, Dmitrieva J, Theatre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori A, Lecut C, Mariman R, Mni M, Oury C, Altukhov I, Alexeev D, Aulchenko Y, Georges M. IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes. Nat Commun 2018; 9:2427.
21.06.2018IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
21.06.2018Nat Commun 2018; 9:2427
Momozawa Yukihide, Hoentjen Frank, Löwenberg Mark, Oldenburg Bas, Pierik Marieke J, Vander Meulen-de Jong Andrea E, Janneke van der Woude C, Visschedijk Marijn C, International IBD Genetics Consortium, Lathrop Mark, Hugot Jean-Pierre, Weersma Rinse K, De Vos Martine, Franchimont Denis, Vermeire Severine, Kubo Michiaki, Louis Edouard, Bouma Gerd, Amininejad Leila, Dmitrieva Julia, Theatre Emilie, Deffontaine Valérie, Rahmouni Souad, Charloteaux Benoît, Crins François, Docampo Elisa, Elansary Mahmoud, Gori Ann-Stephan, Lecut Christelle, Mariman Rob, Mni Myriam, Oury Cécile, Altukhov Ilya, Alexeev Dmitry, Aulchenko Yuri, Georges Michel