Denis Franchimont
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
Momozawa Y, Hoentjen F, Löwenberg M, Oldenburg B, Pierik M, Vander Meulen-de Jong A, Janneke van der Woude C, Visschedijk M, International IBD Genetics Consortium, Lathrop M, Hugot J, Weersma R, De Vos M, Franchimont D, Vermeire S, Kubo M, Louis E, Bouma G, Amininejad L, Dmitrieva J, Theatre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori A, Lecut C, Mariman R, Mni M, Oury C, Altukhov I, Alexeev D, Aulchenko Y, Georges M. IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes. Nat Commun 2018; 9:2427.
21.06.2018IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
21.06.2018Nat Commun 2018; 9:2427
Momozawa Yukihide, Hoentjen Frank, Löwenberg Mark, Oldenburg Bas, Pierik Marieke J, Vander Meulen-de Jong Andrea E, Janneke van der Woude C, Visschedijk Marijn C, International IBD Genetics Consortium, Lathrop Mark, Hugot Jean-Pierre, Weersma Rinse K, De Vos Martine, Franchimont Denis, Vermeire Severine, Kubo Michiaki, Louis Edouard, Bouma Gerd, Amininejad Leila, Dmitrieva Julia, Theatre Emilie, Deffontaine Valérie, Rahmouni Souad, Charloteaux Benoît, Crins François, Docampo Elisa, Elansary Mahmoud, Gori Ann-Stephan, Lecut Christelle, Mariman Rob, Mni Myriam, Oury Cécile, Altukhov Ilya, Alexeev Dmitry, Aulchenko Yuri, Georges Michel
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Kupcinskas L, Potocnik U, Prescott N, Regueiro M, Rotter J, Russell R, Sanderson J, Sans M, Satsangi J, Schreiber S, Simms L, Sventoraityte J, Ponsioen C, Palmieri O, Kugathasan S, Latiano A, Laukens D, Lawrance I, Lees C, Louis E, Mahy G, Mansfield J, Morgan A, Mowat C, Newman W, Targan S, Taylor K, Tremelling M, Hakonarson H, Brant S, Radford-Smith G, Mathew C, Rioux J, Schadt E, Daly M, Franke A, Parkes M, Vermeire S, Barrett J, Annese V, Silverberg M, Verspaget H, De Vos M, Wijmenga C, Wilson D, Winkelmann J, Xavier R, Zeissig S, Zhang B, Zhang C, Zhao H, Cho J, Karlsen T, Jostins L, Theatre E, Spain S, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar J, Ahmad T, Amininejad L, Ananthakrishnan A, Andersen V, Cleynen I, Ning K, Ripke S, Weersma R, Duerr R, McGovern D, Hui K, Lee J, Schumm L, Sharma Y, Anderson C, Essers J, Mitrovic M, Andrews J, Baidoo L, Balschun T, Ferguson L, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Ellinghaus D, Edwards C, Bampton P, Bitton A, Boucher G, Brand S, Büning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney K, Dubinsky M, Hu X. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature 2012; 491:119-24.
01.11.2012Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
01.11.2012Nature 2012; 491:119-24
Kupcinskas Limas, Potocnik Uros, Prescott Natalie J, Regueiro Miguel, Rotter Jerome I, Russell Richard K, Sanderson Jeremy D, Sans Miquel, Satsangi Jack, Schreiber Stefan, Simms Lisa A, Sventoraityte Jurgita, Ponsioen Cyriel Y, Palmieri Orazio, Kugathasan Subra, Latiano Anna, Laukens Debby, Lawrance Ian C, Lees Charlie W, Louis Edouard, Mahy Gillian, Mansfield John, Morgan Angharad R, Mowat Craig, Newman William, Targan Stephan R, Taylor Kent D, Tremelling Mark, Hakonarson Hakon, Brant Steven R, Radford-Smith Graham, Mathew Christopher G, Rioux John D, Schadt Eric E, Daly Mark J, Franke Andre, Parkes Miles, Vermeire Severine, Barrett Jeffrey C, Annese Vito, Silverberg Mark S, Verspaget Hein W, De Vos Martine, Wijmenga Cisca, Wilson David C, Winkelmann Juliane, Xavier Ramnik J, Zeissig Sebastian, Zhang Bin, Zhang Clarence K, Zhao Hongyu, Cho Judy H, Karlsen Tom H, Jostins Luke, Theatre Emilie, Spain Sarah L, Raychaudhuri Soumya, Goyette Philippe, Wei Zhi, Abraham Clara, Achkar Jean-Paul, Ahmad Tariq, Amininejad Leila, Ananthakrishnan Ashwin N, Andersen Vibeke, Cleynen Isabelle, Ning Kaida, Ripke Stephan, Weersma Rinse K, Duerr Richard H, McGovern Dermot P, Hui Ken Y, Lee James C, Schumm L Philip, Sharma Yashoda, Anderson Carl A, Essers Jonah, Mitrovic Mitja, Andrews Jane M, Baidoo Leonard, Balschun Tobias, Ferguson Lynnette R, Franchimont Denis, Fransen Karin, Gearry Richard, Georges Michel, Gieger Christian, Glas Jürgen, Haritunians Talin, Hart Ailsa, Hawkey Chris, Hedl Matija, Ellinghaus David, Edwards Cathryn, Bampton Peter A, Bitton Alain, Boucher Gabrielle, Brand Stephan, Büning Carsten, Cohain Ariella, Cichon Sven, D'Amato Mauro, De Jong Dirk, Devaney Kathy L, Dubinsky Marla, Hu Xinli
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Phillips A, van den Berg L, Vatn M, Verspaget H, Walters T, Wijmenga C, Wilson D, Westra H, Xavier R, Zhao Z, Ponsioen C, Andersen V, Torkvist L, Targan S, Steinhart A, Prescott N, Proctor D, Roberts R, Russell R, Rutgeerts P, Sanderson J, Sans M, Schumm P, Seibold F, Sharma Y, Simms L, Seielstad M, Gazouli M, Anagnou N, Satsangi J, Cho J, Schreiber S, Daly M, Barrett J, Parkes M, Annese V, Hakonarson H, Radford-Smith G, Duerr R, Vermeire S, Weersma R, Chamaillard M, Brant S, Karlsen T, Kupcinskas L, Sventoraityte J, Mansfield J, Kugathasan S, Silverberg M, Halfvarson J, Rotter J, Mathew C, Griffiths A, Gearry R, Ahmad T, Rioux J, Panés J, Anderson C, Baldassano R, Barclay M, Bayless T, Brand S, Büning C, Colombel J, Denson L, De Vos M, Dubinsky M, Edwards C, Ellinghaus D, Fehrmann R, Baidoo L, Bumpstead S, Boucher G, Lees C, Franke A, D'Amato M, Taylor K, Lee J, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Floyd J, Florin T, Libioulle C, Louis E, McGovern D, Milla M, Montgomery G, Morley K, Mowat C, Ng A, Newman W, Ophoff R, Papi L, Palmieri O, Levine A, Lemann M, Franchimont D, Franke L, Georges M, Glas J, Glazer N, Guthery S, Haritunians T, Hayward N, Hugot J, Jobin G, Laukens D, Lawrance I, Peyrin-Biroulet L. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet 2011; 43:246-52.
06.02.2011Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
06.02.2011Nat Genet 2011; 43:246-52
Phillips Anne, van den Berg Leonard H, Vatn Morten, Verspaget Hein, Walters Thomas, Wijmenga Cisca, Wilson David C, Westra Harm-Jan, Xavier Ramnik J, Zhao Zhen Z, Ponsioen Cyriel Y, Andersen Vibeke, Torkvist Leif, Targan Stephan R, Steinhart A Hillary, Prescott Natalie J, Proctor Deborah D, Roberts Rebecca, Russell Richard, Rutgeerts Paul, Sanderson Jeremy, Sans Miquel, Schumm Philip, Seibold Frank, Sharma Yashoda, Simms Lisa A, Seielstad Mark, Gazouli Maria, Anagnou Nicholas P, Satsangi Jack, Cho Judy H, Schreiber Stefan, Daly Mark J, Barrett Jeffrey C, Parkes Miles, Annese Vito, Hakonarson Hakon, Radford-Smith Graham, Duerr Richard H, Vermeire Severine, Weersma Rinse K, Chamaillard Mathias, Brant Steven R, Karlsen Tom H, Kupcinskas Limas, Sventoraityte Jurgita, Mansfield John C, Kugathasan Subra, Silverberg Mark S, Halfvarson Jonas, Rotter Jerome I, Mathew Christopher G, Griffiths Anne M, Gearry Richard, Ahmad Tariq, Rioux John D, Panés Julián, Anderson Carl A, Baldassano Robert N, Barclay Murray, Bayless Theodore M, Brand Stephan, Büning Carsten, Colombel Jean-Frédéric, Denson Lee A, De Vos Martine, Dubinsky Marla, Edwards Cathryn, Ellinghaus David, Fehrmann Rudolf S N, Baidoo Leonard, Bumpstead Suzannah, Boucher Gabrielle, Lees Charlie W, Franke Andre, D'Amato Mauro, Taylor Kent D, Lee James C, Goyette Philippe, Imielinski Marcin, Latiano Anna, Lagacé Caroline, Scott Regan, Amininejad Leila, Floyd James A B, Florin Timothy, Libioulle Cecile, Louis Edouard, McGovern Dermot P, Milla Monica, Montgomery Grant W, Morley Katherine I, Mowat Craig, Ng Aylwin, Newman William, Ophoff Roel A, Papi Laura, Palmieri Orazio, Levine Arie, Lemann Marc, Franchimont Denis, Franke Lude, Georges Michel, Glas Jürgen, Glazer Nicole L, Guthery Stephen L, Haritunians Talin, Hayward Nicholas K, Hugot Jean-Pierre, Jobin Gilles, Laukens Debby, Lawrance Ian, Peyrin-Biroulet Laurent
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Glas J, Mowat C, Newman W, Panés J, Phillips A, Proctor D, Regueiro M, Russell R, Rutgeerts P, Sanderson J, Sans M, Louis E, Libioulle C, Van Gossum A, Guthery S, Halfvarson J, Verspaget H, Hugot J, Karban A, Laukens D, Lawrance I, Lemann M, Levine A, Seibold F, Steinhart A, Mansfield J, Vermeire S, Duerr R, Silverberg M, Satsangi J, Schreiber S, Cho J, Annese V, Hakonarson H, Daly M, Griffiths A, Kugathasan S, Stokkers P, Torkvist L, Kullak-Ublick G, Wilson D, Walters T, Targan S, Brant S, Rioux J, D'Amato M, Weersma R, Parkes M, Franke A, Ellinghaus D, Festen E, Georges M, Green T, Haritunians T, Jostins L, Latiano A, Mathew C, Montgomery G, Prescott N, Bumpstead S, Bis J, McGovern D, Barrett J, Wang K, Radford-Smith G, Ahmad T, Lees C, Balschun T, Lee J, Roberts R, Anderson C, Raychaudhuri S, Rotter J, Colombel J, Cottone M, Stronati L, Denson T, De Vos M, D'Inca R, Dubinsky M, Edwards C, Florin T, Franchimont D, Cohen A, Büning C, Schumm P, Sharma Y, Simms L, Taylor K, Whiteman D, Wijmenga C, Baldassano R, Barclay M, Bayless T, Brand S, Gearry R. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet 2010; 42:1118-25.
01.12.2010Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
01.12.2010Nat Genet 2010; 42:1118-25
Glas Jürgen, Mowat Craig, Newman William, Panés Julián, Phillips Anne, Proctor Deborah D, Regueiro Miguel, Russell Richard, Rutgeerts Paul, Sanderson Jeremy, Sans Miquel, Louis Edouard, Libioulle Cecile, Van Gossum Andre, Guthery Stephen L, Halfvarson Jonas, Verspaget Hein W, Hugot Jean-Pierre, Karban Amir, Laukens Debby, Lawrance Ian, Lemann Marc, Levine Arie, Seibold Frank, Steinhart A Hillary, Mansfield John C, Vermeire Severine, Duerr Richard H, Silverberg Mark S, Satsangi Jack, Schreiber Stefan, Cho Judy H, Annese Vito, Hakonarson Hakon, Daly Mark J, Griffiths Anne M, Kugathasan Subra, Stokkers Pieter C F, Torkvist Leif, Kullak-Ublick Gerd, Wilson David, Walters Thomas, Targan Stephan R, Brant Steven R, Rioux John D, D'Amato Mauro, Weersma Rinse K, Parkes Miles, Franke Andre, Ellinghaus David, Festen Eleonora M, Georges Michel, Green Todd, Haritunians Talin, Jostins Luke, Latiano Anna, Mathew Christopher G, Montgomery Grant W, Prescott Natalie J, Bumpstead Suzanne, Bis Joshua C, McGovern Dermot P B, Barrett Jeffrey C, Wang Kai, Radford-Smith Graham L, Ahmad Tariq, Lees Charlie W, Balschun Tobias, Lee James, Roberts Rebecca, Anderson Carl A, Raychaudhuri Soumya, Rotter Jerome I, Colombel Jean-Frederick, Cottone Mario, Stronati Laura, Denson Ted, De Vos Martine, D'Inca Renata, Dubinsky Marla, Edwards Cathryn, Florin Tim, Franchimont Denis, Cohen Albert, Büning Carsten, Schumm Philip, Sharma Yashoda, Simms Lisa A, Taylor Kent D, Whiteman David, Wijmenga Cisca, Baldassano Robert N, Barclay Murray, Bayless Theodore M, Brand Stephan, Gearry Richard