Jean-Paul Achkar
A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition
Li D, Devlin B, Sharma Y, Torkvist L, Targan S, Stempak J, Simms L, Regueiro M, Proctor D, Borneman J, Hakonarson H, McGovern D, Braun J, Cho J, Silverberg M, Rioux J, Brant S, Daly M, Xavier R, Milgrom R, Glas J, Halfvarson J, Radford-Smith G, Brand S, D'Amato M, Hui K, Jacobs J, Haritunians T, Achkar J, Niess J, Kugathasan S, Fiocchi C, Dubinsky M, Baidoo L, Aumais G, Ananthakrishnan A, Klei L, Schumm L, Büning C, Duerr R. A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition. Gastroenterology 2016; 151:724-32.
01.08.2016A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition
01.08.2016Gastroenterology 2016; 151:724-32
Li Dalin, Devlin Bernie, Sharma Yashoda, Torkvist Leif, Targan Stephan R, Stempak Joanne M, Simms Lisa A, Regueiro Miguel, Proctor Deborah D, Borneman James, Hakonarson Hakon, McGovern Dermot P B, Braun Jonathan, Cho Judy H, Silverberg Mark S, Rioux John D, Brant Steven R, Daly Mark, Xavier Ramnik J, Milgrom Raquel, Glas Jürgen, Halfvarson Jonas, Radford-Smith Graham, Brand Stephan, D'Amato Mauro, Hui Ken Y, Jacobs Jonathan P, Haritunians Talin, Achkar Jean-Paul, Niess Jan-Hendrik, Kugathasan Subra, Fiocchi Claudio, Dubinsky Marla, Baidoo Leonard, Aumais Guy, Ananthakrishnan Ashwin, Klei Lambertus, Schumm L Philip, Büning Carsten, Duerr Richard H
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
Thomsen I, Vatn M, Silverberg M, Duerr R, Padyukov L, Brand S, Sans M, Annese V, Achkar J, Melum E, Durie P, Sandford R, Mayr G, König I, Hveem K, Cleynen I, Gutierrez-Achury J, Ricaño-Ponce I, van Heel D, Björnsson E, Boberg K, Marschall H, Schreiber S, Manns M, Färkkilä M, Dale A, Chapman R, Lazaridis K, Franke A, Anderson C, Cho J, Bergquist A, Alexander G, Chazouillères O, Bowlus C, Wijmenga C, Schrumpf E, Vermeire S, Albrecht M, Rioux J, Karlsen T, Næss S, Liu J, Gotthardt D, Pares A, Ellinghaus D, Shah T, Juran B, Milkiewicz P, Rust C, Schramm C, Hirschfield G, Invernizzi P, Eksteen B, Hov J, Folseraas T, Ellinghaus E, Rushbrook S, Doncheva N, Andreassen O, Weersma R, Weismüller T, Müller T, Srivastava B, Saarela J, Leppa V, Dorfman R, Alvaro D, Floreani A, Onengut-Gumuscu S, Rich S, Thompson W, Mason A, Teufel A, Sterneck M, Dalekos G, Nöthen M, Herms S, Winkelmann J, Mitrovic M, Braun F, Ponsioen C, Croucher P, Schork A. Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. Nat Genet 2013; 45:670-5.
21.04.2013Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
21.04.2013Nat Genet 2013; 45:670-5
Thomsen Ingo, Vatn Morten H, Silverberg Mark S, Duerr Richard H, Padyukov Leonid, Brand Stephan, Sans Miquel, Annese Vito, Achkar Jean-Paul, Melum Espen, Durie Peter R, Sandford Richard N, Mayr Gabriele, König Inke R, Hveem Kristian, Cleynen Isabelle, Gutierrez-Achury Javier, Ricaño-Ponce Isis, van Heel David, Björnsson Einar, Boberg Kirsten Muri, Marschall Hanns-Ulrich, Schreiber Stefan, Manns Michael P, Färkkilä Martti, Dale Anders M, Chapman Roger W, Lazaridis Konstantinos N, Franke Andre, Anderson Carl A, Cho Judy, Bergquist Annika, Alexander Graeme, Chazouillères Olivier, Bowlus Christopher L, Wijmenga Cisca, Schrumpf Erik, Vermeire Severine, Albrecht Mario, Rioux John D, Karlsen Tom H, Næss Sigrid, Liu Jimmy Z, Gotthardt Daniel Nils, Pares Albert, Ellinghaus David, Shah Tejas, Juran Brian D, Milkiewicz Piotr, Rust Christian, Schramm Christoph, Hirschfield Gideon M, Invernizzi Pietro, Eksteen Bertus, Hov Johannes Roksund, Folseraas Trine, Ellinghaus Eva, Rushbrook Simon M, Doncheva Nadezhda T, Andreassen Ole A, Weersma Rinse K, Weismüller Tobias J, Müller Tobias, Srivastava Brijesh, Saarela Janna, Leppa Virpi, Dorfman Ruslan, Alvaro Domenico, Floreani Annarosa, Onengut-Gumuscu Suna, Rich Stephen S, Thompson Wesley K, Mason Andrew L, Teufel Andreas, Sterneck Martina, Dalekos Georgios, Nöthen Markus M, Herms Stefan, Winkelmann Juliane, Mitrovic Mitja, Braun Felix, Ponsioen Cyriel Y, Croucher Peter J P, Schork Andrew J
PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites
Glas J, Duerr R, Franke A, Kamboh M, Achkar J, Balschun T, Müller-Myhsok B, Wolf C, Olszak T, Wetzke M, Diegelmann J, Pasciuto G, Czamara D, Seiderer J, Brand S. PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites. PloS one 2012; 7:e52873.
27.12.2012PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites
27.12.2012PloS one 2012; 7:e52873
Glas Jürgen, Duerr Richard H, Franke Andre, Kamboh M Ilyas, Achkar Jean-Paul, Balschun Tobias, Müller-Myhsok Bertram, Wolf Christiane, Olszak Torsten, Wetzke Martin, Diegelmann Julia, Pasciuto Giulia, Czamara Darina, Seiderer Julia, Brand Stephan
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Kupcinskas L, Potocnik U, Prescott N, Regueiro M, Rotter J, Russell R, Sanderson J, Sans M, Satsangi J, Schreiber S, Simms L, Sventoraityte J, Ponsioen C, Palmieri O, Kugathasan S, Latiano A, Laukens D, Lawrance I, Lees C, Louis E, Mahy G, Mansfield J, Morgan A, Mowat C, Newman W, Targan S, Taylor K, Tremelling M, Hakonarson H, Brant S, Radford-Smith G, Mathew C, Rioux J, Schadt E, Daly M, Franke A, Parkes M, Vermeire S, Barrett J, Annese V, Silverberg M, Verspaget H, De Vos M, Wijmenga C, Wilson D, Winkelmann J, Xavier R, Zeissig S, Zhang B, Zhang C, Zhao H, Cho J, Karlsen T, Jostins L, Theatre E, Spain S, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar J, Ahmad T, Amininejad L, Ananthakrishnan A, Andersen V, Cleynen I, Ning K, Ripke S, Weersma R, Duerr R, McGovern D, Hui K, Lee J, Schumm L, Sharma Y, Anderson C, Essers J, Mitrovic M, Andrews J, Baidoo L, Balschun T, Ferguson L, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Ellinghaus D, Edwards C, Bampton P, Bitton A, Boucher G, Brand S, Büning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney K, Dubinsky M, Hu X. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature 2012; 491:119-24.
01.11.2012Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
01.11.2012Nature 2012; 491:119-24
Kupcinskas Limas, Potocnik Uros, Prescott Natalie J, Regueiro Miguel, Rotter Jerome I, Russell Richard K, Sanderson Jeremy D, Sans Miquel, Satsangi Jack, Schreiber Stefan, Simms Lisa A, Sventoraityte Jurgita, Ponsioen Cyriel Y, Palmieri Orazio, Kugathasan Subra, Latiano Anna, Laukens Debby, Lawrance Ian C, Lees Charlie W, Louis Edouard, Mahy Gillian, Mansfield John, Morgan Angharad R, Mowat Craig, Newman William, Targan Stephan R, Taylor Kent D, Tremelling Mark, Hakonarson Hakon, Brant Steven R, Radford-Smith Graham, Mathew Christopher G, Rioux John D, Schadt Eric E, Daly Mark J, Franke Andre, Parkes Miles, Vermeire Severine, Barrett Jeffrey C, Annese Vito, Silverberg Mark S, Verspaget Hein W, De Vos Martine, Wijmenga Cisca, Wilson David C, Winkelmann Juliane, Xavier Ramnik J, Zeissig Sebastian, Zhang Bin, Zhang Clarence K, Zhao Hongyu, Cho Judy H, Karlsen Tom H, Jostins Luke, Theatre Emilie, Spain Sarah L, Raychaudhuri Soumya, Goyette Philippe, Wei Zhi, Abraham Clara, Achkar Jean-Paul, Ahmad Tariq, Amininejad Leila, Ananthakrishnan Ashwin N, Andersen Vibeke, Cleynen Isabelle, Ning Kaida, Ripke Stephan, Weersma Rinse K, Duerr Richard H, McGovern Dermot P, Hui Ken Y, Lee James C, Schumm L Philip, Sharma Yashoda, Anderson Carl A, Essers Jonah, Mitrovic Mitja, Andrews Jane M, Baidoo Leonard, Balschun Tobias, Ferguson Lynnette R, Franchimont Denis, Fransen Karin, Gearry Richard, Georges Michel, Gieger Christian, Glas Jürgen, Haritunians Talin, Hart Ailsa, Hawkey Chris, Hedl Matija, Ellinghaus David, Edwards Cathryn, Bampton Peter A, Bitton Alain, Boucher Gabrielle, Brand Stephan, Büning Carsten, Cohain Ariella, Cichon Sven, D'Amato Mauro, De Jong Dirk, Devaney Kathy L, Dubinsky Marla, Hu Xinli