Simone Pfennig
CEACAM6 gene variants in inflammatory bowel disease
Glas J, Czamara D, Diegelmann J, Müller-Myhsok B, Lohse P, Wolf C, Ochsenkühn T, Göke B, Lass U, Olszak T, Beigel F, Weidinger M, Pfennig S, Tillack C, Fries C, Seiderer J, Brand S. CEACAM6 gene variants in inflammatory bowel disease. PloS one 2011; 6:e19319.
29.04.2011CEACAM6 gene variants in inflammatory bowel disease
29.04.2011PloS one 2011; 6:e19319
Glas Jürgen, Czamara Darina, Diegelmann Julia, Müller-Myhsok Bertram, Lohse Peter, Wolf Christiane, Ochsenkühn Thomas, Göke Burkhard, Lass Ulrich, Olszak Torsten, Beigel Florian, Weidinger Maria, Pfennig Simone, Tillack Cornelia, Fries Christoph, Seiderer Julia, Brand Stephan
Formation of antinuclear and double-strand DNA antibodies and frequency of lupus-like syndrome in anti-TNF-α antibody-treated patients with inflammatory bowel disease
Beigel F, Schnitzler F, Paul Laubender R, Pfennig S, Weidinger M, Göke B, Seiderer J, Ochsenkühn T, Brand S. Formation of antinuclear and double-strand DNA antibodies and frequency of lupus-like syndrome in anti-TNF-α antibody-treated patients with inflammatory bowel disease. Inflamm Bowel Dis 2011; 17:91-8.
01.01.2011Formation of antinuclear and double-strand DNA antibodies and frequency of lupus-like syndrome in anti-TNF-α antibody-treated patients with inflammatory bowel disease
01.01.2011Inflamm Bowel Dis 2011; 17:91-8
Beigel Florian, Schnitzler Fabian, Paul Laubender Rüdiger, Pfennig Simone, Weidinger Maria, Göke Burkhard, Seiderer Julia, Ochsenkühn Thomas, Brand Stephan
The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants
Glas J, Czamara D, Diegelmann J, Lohse P, Ochsenkühn T, Göke B, Müller-Myhsok B, Weidinger M, Laubender R, Olszak T, Jürgens M, Beigel F, Pfennig S, Tillack C, Seiderer J, Brand S. The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants. PloS one 2010; 5:e14466.
30.12.2010The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants
30.12.2010PloS one 2010; 5:e14466
Glas Jürgen, Czamara Darina, Diegelmann Julia, Lohse Peter, Ochsenkühn Thomas, Göke Burkhard, Müller-Myhsok Bertram, Weidinger Maria, Laubender Rüdiger P, Olszak Torsten, Jürgens Matthias, Beigel Florian, Pfennig Simone, Tillack Cornelia, Seiderer Julia, Brand Stephan
Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease
Glas J, Czamara D, Diegelmann J, Müller-Myhsok B, Folwaczny M, Ochsenkühn T, Göke B, Weidinger M, Olszak T, Beigel F, Wetzke M, Pfennig S, Tengler B, Fischer D, Seiderer J, Brand S. Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease. Inflamm Bowel Dis 2010; 17:1917-24.
03.12.2010Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease
03.12.2010Inflamm Bowel Dis 2010; 17:1917-24
Glas Jürgen, Czamara Darina, Diegelmann Julia, Müller-Myhsok Bertram, Folwaczny Matthias, Ochsenkühn Thomas, Göke Burkhard, Weidinger Maria, Olszak Torsten, Beigel Florian, Wetzke Martin, Pfennig Simone, Tengler Barbara, Fischer Daniel, Seiderer Julia, Brand Stephan
Role of PPARG gene variants in inflammatory bowel disease
Glas J, Roeske D, Diegelmann J, Müller-Myhsok B, Ochsenkühn T, Göke B, Paschos E, Wetzke M, Pfennig S, Markus C, Seiderer J, Brand S. Role of PPARG gene variants in inflammatory bowel disease. Inflamm Bowel Dis 2010; 17:1057-8.
18.08.2010Role of PPARG gene variants in inflammatory bowel disease
18.08.2010Inflamm Bowel Dis 2010; 17:1057-8
Glas Jürgen, Roeske Darina, Diegelmann Julia, Müller-Myhsok Bertram, Ochsenkühn Thomas, Göke Burkhard, Paschos Ekaterini, Wetzke Martin, Pfennig Simone, Markus Christian, Seiderer Julia, Brand Stephan
Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset
Glas J, Roeske D, Müller-Myhsok B, Diegelmann J, Ochsenkühn T, Göke B, Folwaczny M, Lohse P, Epplen J, Klein W, Pfennig S, Weidinger M, Beigel F, Fries C, Nagy M, Seiderer J, Brand S. Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset. PloS one 2010; 5:e10373.
29.04.2010Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset
29.04.2010PloS one 2010; 5:e10373
Glas Jürgen, Roeske Darina, Müller-Myhsok Bertram, Diegelmann Julia, Ochsenkühn Thomas, Göke Burkhard, Folwaczny Matthias, Lohse Peter, Epplen Jörg T, Klein Wolfram, Pfennig Simone, Weidinger Maria, Beigel Florian, Fries Christoph, Nagy Melinda, Seiderer Julia, Brand Stephan
The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype
Jürgens M, Herrmann K, Lohse P, Göke B, Kreis M, Schnitzler F, Weidinger M, Beigel F, Tillack C, Pfennig S, Wagner J, Wetzke M, Glas J, Seiderer J, Laubender R, Brand S, Ochsenkühn T. The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype. J Gastroenterol 2010; 45:721-31.
29.04.2010The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype
29.04.2010J Gastroenterol 2010; 45:721-31
Jürgens Matthias, Herrmann Karin, Lohse Peter, Göke Burkhard, Kreis Martin E, Schnitzler Fabian, Weidinger Maria, Beigel Florian, Tillack Cornelia, Pfennig Simone, Wagner Johanna, Wetzke Martin, Glas Jürgen, Seiderer Julia, Laubender Rüdiger P, Brand Stephan, Ochsenkühn Thomas
Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis
Jürgens M, Ochsenkühn T, Glas J, Göke B, Lohse P, Tillack C, Schnitzler F, Stallhofer J, Pfennig S, Beigel F, Wetzke M, Wagner J, Seiderer J, Weidinger M, Hartl F, Laubender R, Brand S. Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis. Am J Gastroenterol 2010; 105:1811-9.
02.03.2010Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis
02.03.2010Am J Gastroenterol 2010; 105:1811-9
Jürgens Matthias, Ochsenkühn Thomas, Glas Jürgen, Göke Burkhard, Lohse Peter, Tillack Cornelia, Schnitzler Fabian, Stallhofer Johannes, Pfennig Simone, Beigel Florian, Wetzke Martin, Wagner Johanna, Seiderer Julia, Weidinger Maria, Hartl Franziska, Laubender Rüdiger P, Brand Stephan
The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease
Storr M, Emmerdinger D, Diegelmann J, Pfennig S, Ochsenkühn T, Göke B, Lohse P, Brand S. The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease. PloS one 2010; 5:e9453.
26.02.2010The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease
26.02.2010PloS one 2010; 5:e9453
Storr Martin, Emmerdinger Dominik, Diegelmann Julia, Pfennig Simone, Ochsenkühn Thomas, Göke Burkhard, Lohse Peter, Brand Stephan
Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease
Glas J, Müller-Myhsok B, Ochsenkühn T, Göke B, Lohse P, Folwaczny M, Koletzko S, Lacher M, Schiemann U, Griga T, Epplen J, Klein W, Pfennig S, Wetzke M, Ripke S, Stallhofer J, Brand S. Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease. Am J Gastroenterol 2009; 104:1737-44.
19.05.2009Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease
19.05.2009Am J Gastroenterol 2009; 104:1737-44
Glas Jürgen, Müller-Myhsok Bertram, Ochsenkühn Thomas, Göke Burkhard, Lohse Peter, Folwaczny Matthias, Koletzko Sibylle, Lacher Martin, Schiemann Uwe, Griga Thomas, Epplen Jörg T, Klein Wolfram, Pfennig Simone, Wetzke Martin, Ripke Stephan, Stallhofer Johannes, Brand Stephan
rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population
Glas J, Klein W, Epplen J, Schiemann U, Mussack T, Lohse P, Göke B, Ochsenkühn T, Folwaczny M, Müller-Myhsok B, Griga T, Jürgens M, Stallhofer J, Seiderer J, Pasciuto G, Tillack C, Diegelmann J, Pfennig S, Konrad A, Schmechel S, Wetzke M, Török H, Brand S. rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. Am J Gastroenterol 2009; 104:665-72.
03.02.2009rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population
03.02.2009Am J Gastroenterol 2009; 104:665-72
Glas Jürgen, Klein Wolfram, Epplen Jörg T, Schiemann Uwe, Mussack Thomas, Lohse Peter, Göke Burkhard, Ochsenkühn Thomas, Folwaczny Matthias, Müller-Myhsok Bertram, Griga Thomas, Jürgens Matthias, Stallhofer Johannes, Seiderer Julia, Pasciuto Giulia, Tillack Cornelia, Diegelmann Julia, Pfennig Simone, Konrad Astrid, Schmechel Silke, Wetzke Martin, Török Helga-Paula, Brand Stephan
Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD
Seiderer J, Lohse P, Müller-Myhsok B, Ochsenkühn T, Göke B, Konrad A, Schmechel S, Jürgens M, Pfennig S, Tillack C, Stallhofer J, Glas J, Diegelmann J, Elben I, Brand S. Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD. Inflamm Bowel Dis 2008; 14:437-45.
01.04.2008Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD
01.04.2008Inflamm Bowel Dis 2008; 14:437-45
Seiderer Julia, Lohse Peter, Müller-Myhsok Bertram, Ochsenkühn Thomas, Göke Burkhard, Konrad Astrid, Schmechel Silke, Jürgens Matthias, Pfennig Simone, Tillack Cornelia, Stallhofer Johannes, Glas Jürgen, Diegelmann Julia, Elben Ira, Brand Stephan
Genotype-phenotype analysis of the CXCL16 p.Ala181Val polymorphism in inflammatory bowel disease
Seiderer J, Reinecker H, Lohse P, Ochsenkühn T, Göke B, Müller-Myhsok B, Jürgens M, Pfennig S, Niess J, Glas J, Tillack C, Leistner D, Dambacher J, Brand S. Genotype-phenotype analysis of the CXCL16 p.Ala181Val polymorphism in inflammatory bowel disease. Clin Immunol 2008; 127:49-55.
11.01.2008Genotype-phenotype analysis of the CXCL16 p.Ala181Val polymorphism in inflammatory bowel disease
11.01.2008Clin Immunol 2008; 127:49-55
Seiderer Julia, Reinecker Hans-Christian, Lohse Peter, Ochsenkühn Thomas, Göke Burkhard, Müller-Myhsok Bertram, Jürgens Matthias, Pfennig Simone, Niess Jan-Hendrik, Glas Jürgen, Tillack Cornelia, Leistner Dorothea, Dambacher Julia, Brand Stephan
The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population
Glas J, Klein W, Epplen J, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Mussack T, Folwaczny M, Müller-Myhsok B, Griga T, Haller D, Pfennig S, Konrad A, Schmechel S, Dambacher J, Seiderer J, Schroff F, Wetzke M, Roeske D, Török H, Tonenchi L, Brand S. The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population. Am J Gastroenterol 2007; 103:682-91.
20.12.2007The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population
20.12.2007Am J Gastroenterol 2007; 103:682-91
Glas Jürgen, Klein Wolfram, Epplen Jörg T, Folwaczny Christian, Lohse Peter, Göke Burkhard, Ochsenkühn Thomas, Mussack Thomas, Folwaczny Matthias, Müller-Myhsok Bertram, Griga Thomas, Haller Dirk, Pfennig Simone, Konrad Astrid, Schmechel Silke, Dambacher Julia, Seiderer Julia, Schroff Frieder, Wetzke Martin, Roeske Darina, Török Helga-Paula, Tonenchi Laurian, Brand Stephan
rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants
Glas J, Epplen J, Schiemann U, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Müller-Myhsok B, Folwaczny M, Mussack T, Klein W, Griga T, Maier K, Seiderer J, Wetzke M, Konrad A, Török H, Schmechel S, Tonenchi L, Grassl C, Dambacher J, Pfennig S, Brand S. rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. PloS one 2007; 2:e819.
05.09.2007rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants
05.09.2007PloS one 2007; 2:e819
Glas Jürgen, Epplen Jörg T, Schiemann Uwe, Folwaczny Christian, Lohse Peter, Göke Burkhard, Ochsenkühn Thomas, Müller-Myhsok Bertram, Folwaczny Matthias, Mussack Thomas, Klein Wolfram, Griga Thomas, Maier Kerstin, Seiderer Julia, Wetzke Martin, Konrad Astrid, Török Helga-Paula, Schmechel Silke, Tonenchi Laurian, Grassl Christine, Dambacher Julia, Pfennig Simone, Brand Stephan
Macrophage migration inhibitory factor (MIF) -173G/C promoter polymorphism influences upper gastrointestinal tract involvement and disease activity in patients with Crohn's disease
Dambacher J, Lohse P, Ochsenkühn T, Göke B, Diebold J, Otte J, Tillack C, Konrad A, Hofbauer K, Pfennig S, Schnitzler F, Sisic Z, Seiderer J, Staudinger T, Brand S. Macrophage migration inhibitory factor (MIF) -173G/C promoter polymorphism influences upper gastrointestinal tract involvement and disease activity in patients with Crohn's disease. Inflamm Bowel Dis 2007; 13:71-82.
01.01.2007Macrophage migration inhibitory factor (MIF) -173G/C promoter polymorphism influences upper gastrointestinal tract involvement and disease activity in patients with Crohn's disease
01.01.2007Inflamm Bowel Dis 2007; 13:71-82
Dambacher Julia, Lohse Peter, Ochsenkühn Thomas, Göke Burkhard, Diebold Joachim, Otte Jan-Michel, Tillack Cornelia, Konrad Astrid, Hofbauer Katrin, Pfennig Simone, Schnitzler Fabian, Sisic Zeljka, Seiderer Julia, Staudinger Tanja, Brand Stephan
Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis
Seiderer J, Lohse P, Göke B, Sackmann M, Tillack C, Dambacher J, Hofbauer K, Herrmann K, Pfennig S, Staudinger T, Brand S, Schnitzler F, Ochsenkühn T. Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis. Scand J Gastroenterol 2006; 41:1421-32.
01.12.2006Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis
01.12.2006Scand J Gastroenterol 2006; 41:1421-32
Seiderer Julia, Lohse Peter, Göke Burkhard, Sackmann Michael, Tillack Cornelia, Dambacher Julia, Hofbauer Katrin, Herrmann Karin, Pfennig Simone, Staudinger Tanja, Brand Stephan, Schnitzler Fabian, Ochsenkühn Thomas
Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study
Seiderer J, Lohse P, Göke B, Schoenberg S, Pfennig S, Crispin A, Hatz R, Schnitzler F, Herrmann K, Brand S, Ochsenkühn T. Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study. Inflamm Bowel Dis 2006; 12:1114-21.
01.12.2006Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study
01.12.2006Inflamm Bowel Dis 2006; 12:1114-21
Seiderer Julia, Lohse Peter, Göke Burkhard, Schoenberg Stefan O, Pfennig Simone, Crispin Alexander, Hatz Rudolf, Schnitzler Fabian, Herrmann Karin A, Brand Stephan, Ochsenkühn Thomas
Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease
Schnitzler F, Ochsenkühn T, Göke B, Tillack C, Seiderer J, Hofbauer K, Pfennig S, Staudinger T, Brand S, Lohse P. Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease. Immunogenetics 2006; 58:99-106.
17.02.2006Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease
17.02.2006Immunogenetics 2006; 58:99-106
Schnitzler Fabian, Ochsenkühn Thomas, Göke Burkhard, Tillack Cornelia, Seiderer Julia, Hofbauer Katrin, Pfennig Simone, Staudinger Tanja, Brand Stephan, Lohse Peter
Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease Phenotype
Brand S, Ochsenkühn T, Göke B, Konrad A, Tillack C, Seiderer J, Pfennig S, Staudinger T, Schnitzler F, Dambacher J, Hofbauer K, Lohse P. Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease Phenotype. Am J Gastroenterol 2006; 101:99-106.
01.01.2006Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease Phenotype
01.01.2006Am J Gastroenterol 2006; 101:99-106
Brand Stephan, Ochsenkühn Thomas, Göke Burkhard, Konrad Astrid, Tillack Cornelia, Seiderer Julia, Pfennig Simone, Staudinger Tanja, Schnitzler Fabian, Dambacher Julia, Hofbauer Katrin, Lohse Peter