Unit
Medizinisches Forschungszentrum
MFZ · Management
Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses
Fasnacht N, Luther S, Ludewig B, Tacchini-Cottier F, MacDonald H, Pinschewer D, Kallert S, Onder L, Chai Q, Auderset F, Favre S, Koch U, Huang H, Radtke F. Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses. J Exp Med 2014; 211:2265-79.
Oct 13, 2014Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses
Oct 13, 2014J Exp Med 2014; 211:2265-79
Fasnacht Nicolas, Luther Sanjiv A, Ludewig Burkhard, Tacchini-Cottier Fabienne, MacDonald H Robson, Pinschewer Daniel D, Kallert Sandra, Onder Lucas, Chai Qian, Auderset Floriane, Favre Stéphanie, Koch Ute, Huang Hsin-Ying, Radtke Freddy
MHC Class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity
Sage A, Hugues S, Reizis B, Hansson G, Reith W, Ludewig B, Harrison J, Grassia G, Ait-Oufella H, Finigan A, Cambrook H, Baker L, Sabir S, Masters L, Maffia P, Murphy D, Mallat Z. MHC Class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity. Circulation 2014; 130:1363-73.
Sep 15, 2014MHC Class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity
Sep 15, 2014Circulation 2014; 130:1363-73
Sage Andrew P, Hugues Stephanie, Reizis Boris, Hansson Göran K, Reith Walter, Ludewig Burkhard, Harrison James E, Grassia Gianluca, Ait-Oufella Hafid, Finigan Alison J, Cambrook Helen, Baker Lauren L, Sabir Suleman R, Masters Leanne M, Maffia Pasquale, Murphy Deirdre, Mallat Ziad
B cell homeostasis and follicle confines are governed by fibroblastic reticular cells
Cremasco V, Carroll M, Ludewig B, Wucherpfennig K, Harvey C, Cremasco F, Chang J, Schildberg F, Nieves-Bonilla J, Cupovic J, Onder L, Woodruff M, Turley S. B cell homeostasis and follicle confines are governed by fibroblastic reticular cells. Nat Immunol 2014; 15:973-81.
Aug 24, 2014B cell homeostasis and follicle confines are governed by fibroblastic reticular cells
Aug 24, 2014Nat Immunol 2014; 15:973-81
Cremasco Viviana, Carroll Michael C, Ludewig Burkhard, Wucherpfennig Kai, Harvey Christopher J, Cremasco Floriana, Chang Jonathan, Schildberg Frank A, Nieves-Bonilla Janice M, Cupovic Jovana, Onder Lucas, Woodruff Matthew C, Turley Shannon J
Plasticity and complexity of B cell responses against persisting pathogens
Pérez Shibayama C, Gil Cruz C, Ludewig B. Plasticity and complexity of B cell responses against persisting pathogens. Immunol Lett 2014; 162:53-8.
Jul 25, 2014Plasticity and complexity of B cell responses against persisting pathogens
Jul 25, 2014Immunol Lett 2014; 162:53-8
Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Ludewig Burkhard
IFN-γ-producing CD4+ T cells promote generation of protective germinal center-derived IgM+ B cell memory against Salmonella Typhi
Pérez Shibayama C, López-Macías C, Isibasi A, Waisman A, Regen T, Scandella E, Onder L, Chai Q, Hisaki E, Cervantes-Barragan L, Pastelin-Palacios R, Gil Cruz C, Ludewig B. IFN-γ-producing CD4+ T cells promote generation of protective germinal center-derived IgM+ B cell memory against Salmonella Typhi. J Immunol 2014; 192:5192-200.
Apr 28, 2014IFN-γ-producing CD4+ T cells promote generation of protective germinal center-derived IgM+ B cell memory against Salmonella Typhi
Apr 28, 2014J Immunol 2014; 192:5192-200
Pérez Shibayama Christian Ivan, López-Macías Constantino, Isibasi Armando, Waisman Ari, Regen Tommy, Scandella Elke, Onder Lucas, Chai Qian, Hisaki Emiliano, Cervantes-Barragan Luisa, Pastelin-Palacios Rodolfo, Gil Cruz Cristina, Ludewig Burkhard
Mathematical models for CFSE labelled lymphocyte dynamics: asymmetry and time-lag in division
Luzyanina T, Cupovic J, Ludewig B, Bocharov G. Mathematical models for CFSE labelled lymphocyte dynamics: asymmetry and time-lag in division. J Math Biol 2013
Dec 13, 2013Mathematical models for CFSE labelled lymphocyte dynamics: asymmetry and time-lag in division
Dec 13, 2013J Math Biol 2013
Luzyanina Tatyana, Cupovic Jovana, Ludewig Burkhard, Bocharov Gennady
Dendritic cell-specific delivery of Flt3L by coronavirus vectors secures induction of therapeutic antitumor immunity
Pérez Shibayama C, Gil Cruz C, Nussbacher M, Allgäuer E, Cervantes-Barragan L, Züst R, Ludewig B. Dendritic cell-specific delivery of Flt3L by coronavirus vectors secures induction of therapeutic antitumor immunity. PloS one 2013; 8:e81442.
Nov 28, 2013Dendritic cell-specific delivery of Flt3L by coronavirus vectors secures induction of therapeutic antitumor immunity
Nov 28, 2013PloS one 2013; 8:e81442
Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Nussbacher Monika, Allgäuer Eva, Cervantes-Barragan Luisa, Züst Roland, Ludewig Burkhard
Systemic minor histocompatibility antigen expression in blood endothelial cells prevents T cell-mediated vascular immunopathology
Caviezel-Firner S, Engeler D, Bolinger B, Onder L, Scandella E, Yu M, Kroczek R, Ludewig B. Systemic minor histocompatibility antigen expression in blood endothelial cells prevents T cell-mediated vascular immunopathology. Eur J Immunol 2013; 43:3233-43.
Sep 6, 2013Systemic minor histocompatibility antigen expression in blood endothelial cells prevents T cell-mediated vascular immunopathology
Sep 6, 2013Eur J Immunol 2013; 43:3233-43
Caviezel-Firner Sonja, Engeler Daniel, Bolinger Beatrice, Onder Lucas, Scandella Elke, Yu Meimei, Kroczek Richard A, Ludewig Burkhard
Asymmetry of Cell Division in CFSE-Based Lymphocyte Proliferation Analysis
Bocharov G, Luzyanina T, Cupovic J, Ludewig B. Asymmetry of Cell Division in CFSE-Based Lymphocyte Proliferation Analysis. Front Immunol 2013; 4:264.
Sep 2, 2013Asymmetry of Cell Division in CFSE-Based Lymphocyte Proliferation Analysis
Sep 2, 2013Front Immunol 2013; 4:264
Bocharov Gennady, Luzyanina Tatyana, Cupovic Jovana, Ludewig Burkhard
Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage
Iolyeva M, Finke D, Chen L, Boyman O, Santambrogio L, Ludewig B, Onder L, Krieg C, Bouchaud G, Häner S, Ecoiffier T, Willrodt A, Proulx S, Aebischer D, Halin C. Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage. Blood 2013; 122:2271-81.
Aug 20, 2013Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage
Aug 20, 2013Blood 2013; 122:2271-81
Iolyeva Maria, Finke Daniela, Chen Lu, Boyman Onur, Santambrogio Laura, Ludewig Burkhard, Onder Lucas, Krieg Carsten, Bouchaud Grégory, Häner Simone, Ecoiffier Tatiana, Willrodt Ann-Helen, Proulx Steven T, Aebischer David, Halin Cornelia
Efficient boosting of the antiviral T cell response in B cell-depleted patients with autoimmune rheumatic diseases following influenza vaccination
Müller R, Maier R, Hoschler K, Zambon M, Ludewig B, Herrmann M, Schulze-Koops H, von Kempis J. Efficient boosting of the antiviral T cell response in B cell-depleted patients with autoimmune rheumatic diseases following influenza vaccination. Clin Exp Rheumatol 2013; 31:723-30.
Jun 14, 2013Efficient boosting of the antiviral T cell response in B cell-depleted patients with autoimmune rheumatic diseases following influenza vaccination
Jun 14, 2013Clin Exp Rheumatol 2013; 31:723-30
Müller Rüdiger, Maier Reinhard, Hoschler Katja, Zambon Maria, Ludewig Burkhard, Herrmann Martin, Schulze-Koops Hendrik, von Kempis Johannes
Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity
Chai Q, Hehlgans T, Stein J, Rülicke T, Thiel V, Luther S, Sparwasser T, Danuser R, Cupovic J, Pérez Shibayama C, Gil Cruz C, Scandella E, Onder L, Ludewig B. Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity. Immunity 2013; 38:1013-24.
Apr 25, 2013Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity
Apr 25, 2013Immunity 2013; 38:1013-24
Chai Qian, Hehlgans Thomas, Stein Jens V, Rülicke Thomas, Thiel Volker, Luther Sanjiv A, Sparwasser Tim, Danuser Renzo, Cupovic Jovana, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Scandella Elke, Onder Lucas, Ludewig Burkhard
Secondary B cell receptor diversification is necessary for T cell mediated neuro-inflammation during experimental autoimmune encephalomyelitis
Galicia G, Boulianne B, Pikor N, Martin A, Gommerman J. Secondary B cell receptor diversification is necessary for T cell mediated neuro-inflammation during experimental autoimmune encephalomyelitis. PloS one 2013; 8:e61478.
Apr 22, 2013Secondary B cell receptor diversification is necessary for T cell mediated neuro-inflammation during experimental autoimmune encephalomyelitis
Apr 22, 2013PloS one 2013; 8:e61478
Galicia Georgina, Boulianne Bryant, Pikor Natalia, Martin Alberto, Gommerman Jennifer L
Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions
Coelho F, Figge M, Sharpe J, Ludewig B, Sailer A, Junt T, Zerwes H, Pieczyk M, Scandella E, Danuser R, Mayer J, Swoger J, Hons M, Soriano S, Natale D, Stein J. Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions. Blood 2013; 121:4101-9.
Apr 4, 2013Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions
Apr 4, 2013Blood 2013; 121:4101-9
Coelho Fernanda M, Figge Marc Thilo, Sharpe James, Ludewig Burkhard, Sailer Andreas W, Junt Tobias, Zerwes Hans-Günter, Pieczyk Markus, Scandella Elke, Danuser Renzo, Mayer Jürgen, Swoger Jim, Hons Miroslav, Soriano Silvia F, Natale Daniela, Stein Jens V
A new model for CD8+ T cell memory inflation based upon a recombinant adenoviral vector.
Bolinger B, Sims S, O'Hara G, de Lara C, Tchilian E, Firner S, Engeler D, Ludewig B, Klenerman P. A new model for CD8+ T cell memory inflation based upon a recombinant adenoviral vector. J Immunol 2013; 190:4162-74.
Mar 18, 2013A new model for CD8+ T cell memory inflation based upon a recombinant adenoviral vector.
Mar 18, 2013J Immunol 2013; 190:4162-74
Bolinger Beatrice, Sims Stuart, O'Hara Geraldine, de Lara Catherine, Tchilian Elma, Firner Sonja, Engeler Daniel, Ludewig Burkhard, Klenerman Paul
Salmonella Typhi OmpS1 and OmpS2 porins are potent protective immunogens with adjuvant properties
Adan M, Edmundo C, Isibasi A, Cecilia B, Marcos F, Isabel B, Rubén L, Gil Cruz C, Pérez Shibayama C, Pastelin-Palacios R, Alejandra T, López-Macías C. Salmonella Typhi OmpS1 and OmpS2 porins are potent protective immunogens with adjuvant properties. Immunology 2013
Feb 23, 2013Salmonella Typhi OmpS1 and OmpS2 porins are potent protective immunogens with adjuvant properties
Feb 23, 2013Immunology 2013
Adan Moreno-Eutimio Mario, Edmundo Calva, Isibasi Armando, Cecilia Bonifaz Laura, Marcos Fernández-Mora, Isabel Baeza, Rubén López-Santiago, Gil Cruz Cristina, Pérez Shibayama Christian Ivan, Pastelin-Palacios Rodolfo, Alejandra Tenorio-Calvo, López-Macías Constantino
Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation.
Onder L, Danuser R, Scandella E, Firner S, Chai Q, Hehlgans T, Stein J, Ludewig B. Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation. J Exp Med 2013; 210:465-73.
Feb 18, 2013Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation.
Feb 18, 2013J Exp Med 2013; 210:465-73
Onder Lucas, Danuser Renzo, Scandella Elke, Firner Sonja, Chai Qian, Hehlgans Thomas, Stein Jens V, Ludewig Burkhard
Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice
Frebel H, Ludewig B, Kurrer M, Loffing-Cueni D, Wagner C, Vogel J, Richter K, Braunschweiler T, Schuepbach R, Nindl V, Oxenius A. Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice. J Exp Med 2012; 209:2485-99.
Dec 10, 2012Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice
Dec 10, 2012J Exp Med 2012; 209:2485-99
Frebel Helge, Ludewig Burkhard, Kurrer Michael, Loffing-Cueni Dominique, Wagner Carsten A, Vogel Johannes, Richter Kirsten, Braunschweiler Thomas, Schuepbach Reto A, Nindl Veronika, Oxenius Annette
A global "imaging'' view on systems approaches in immunology
Ludewig B, Stein J, Sharpe J, Cervantes-Barragan L, Thiel V, Bocharov G. A global "imaging'' view on systems approaches in immunology. Eur J Immunol 2012; 42:3116-25.
Dec 1, 2012A global "imaging'' view on systems approaches in immunology
Dec 1, 2012Eur J Immunol 2012; 42:3116-25
Ludewig Burkhard, Stein Jens V, Sharpe James, Cervantes-Barragan Luisa, Thiel Volker, Bocharov Gennady
Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences
Ilić N, Novkovic M, Guida F, Xhindoli D, Benincasa M, Tossi A, Juretić D. Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences. Biochim Biophys Acta 2012; 1828:1004-1012.
Nov 27, 2012Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences
Nov 27, 2012Biochim Biophys Acta 2012; 1828:1004-1012
Ilić Nada, Novkovic Mario, Guida Filomena, Xhindoli Daniela, Benincasa Monica, Tossi Alessandro, Juretić Davor