Unit
Medizinisches Forschungszentrum
MFZ · Management
Data-driven modelling of the FRC network for studying the fluid flow in the conduit system
Savinkov R, Kislitsyn A, Watson D, van Loon R, Sazonov I, Novkovic M, Onder L, Bocharov G. Data-driven modelling of the FRC network for studying the fluid flow in the conduit system. Engineering Applications of Artificial Intelligence 2016; 62:341-349.
Oct 28, 2016Data-driven modelling of the FRC network for studying the fluid flow in the conduit system
Oct 28, 2016Engineering Applications of Artificial Intelligence 2016; 62:341-349
Savinkov Rostislav, Kislitsyn Alexey, Watson Daniel J., van Loon Raoul, Sazonov Igor, Novkovic Mario, Onder Lucas, Bocharov Gennady
Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche
Bösch M, Sopper S, Zeimet A, Reimer D, Gastl G, Ludewig B, Wolf D. Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche. Biochim Biophys Acta 2016; 1866:276-289.
Oct 15, 2016Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche
Oct 15, 2016Biochim Biophys Acta 2016; 1866:276-289
Bösch Maximilian, Sopper Sieghart, Zeimet Alain G, Reimer Daniel, Gastl Guenther, Ludewig Burkhard, Wolf Dominik
GLUT1-positive recurrent basal cell carcinoma of basosquamous subtype detected by positron emission tomography
Hasan Ali O, Diem S, Aschwanden J, Markert E, Tasman A, Müller J, Flatz L. GLUT1-positive recurrent basal cell carcinoma of basosquamous subtype detected by positron emission tomography. JAAD Case Rep 2016; 2:415-417.
Oct 13, 2016GLUT1-positive recurrent basal cell carcinoma of basosquamous subtype detected by positron emission tomography
Oct 13, 2016JAAD Case Rep 2016; 2:415-417
Hasan Ali Omar, Diem Stefan, Aschwanden Josef, Markert Eva, Tasman Abel-Jan, Müller Joachim, Flatz Lukas
Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer
Hasan Ali O, Diem S, Markert E, Jochum W, Kerl K, French L, Speiser D, Früh M, Flatz L. Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer. Oncoimmunology 2016; 5:e1231292.
Sep 19, 2016Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer
Sep 19, 2016Oncoimmunology 2016; 5:e1231292
Hasan Ali Omar, Diem Stefan, Markert Eva, Jochum Wolfram, Kerl Katrin, French Lars E, Speiser Daniel E, Früh Martin, Flatz Lukas
Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
Novkovic M, Turley S, Bocharov G, Stein J, Scandella E, Cremasco V, Bomze D, Abe J, Cupovic J, Onder L, Ludewig B. Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality. PLoS Biol 2016; 14:e1002515.
Jul 14, 2016Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
Jul 14, 2016PLoS Biol 2016; 14:e1002515
Novkovic Mario, Turley Shannon J, Bocharov Gennady, Stein Jens V, Scandella Elke, Cremasco Viviana, Bomze David, Abe Jun, Cupovic Jovana, Onder Lucas, Ludewig Burkhard
PLGA-microencapsulation protects Salmonella typhi outer membrane proteins from acidic degradation and increases their mucosal immunogenicity
Carreño J, Gander B, López-Macías C, Tanoue Y, Chariatte D, Isibasi A, Pastelin R, Printz A, Gil Cruz C, Pérez Shibayama C, Ludewig B. PLGA-microencapsulation protects Salmonella typhi outer membrane proteins from acidic degradation and increases their mucosal immunogenicity. Vaccine 2016; 34:4263-9.
Jun 29, 2016PLGA-microencapsulation protects Salmonella typhi outer membrane proteins from acidic degradation and increases their mucosal immunogenicity
Jun 29, 2016Vaccine 2016; 34:4263-9
Carreño Juan Manuel, Gander Bruno, López-Macías Constantino, Tanoue Yutaka, Chariatte Dominic, Isibasi Armando, Pastelin Rodolfo, Printz Andrea, Gil Cruz Cristina, Pérez Shibayama Christian Ivan, Ludewig Burkhard
Lymphotoxin-Dependent B Cell-FRC Crosstalk Promotes De Novo Follicle Formation and Antibody Production following Intestinal Helminth Infection
Dubey L, Lebon L, Mosconi I, Yang C, Scandella E, Ludewig B, Luther S, Harris N. Lymphotoxin-Dependent B Cell-FRC Crosstalk Promotes De Novo Follicle Formation and Antibody Production following Intestinal Helminth Infection. Cell Rep 2016; 15:1527-41.
May 5, 2016Lymphotoxin-Dependent B Cell-FRC Crosstalk Promotes De Novo Follicle Formation and Antibody Production following Intestinal Helminth Infection
May 5, 2016Cell Rep 2016; 15:1527-41
Dubey Lalit Kumar, Lebon Luc, Mosconi Ilaria, Yang Chen-Ying, Scandella Elke, Ludewig Burkhard, Luther Sanjiv A, Harris Nicola L
Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL
Cordeiro O, Lanza F, Cupedo T, Ludewig B, Léon C, Yagita H, Rot A, Coles M, Eckly A, Li Z, Bénézech C, Romera-Hernandez M, Alloush F, Rauber S, Brouard N, Chypre M, Mueller C. Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL. PloS one 2016; 11:e0151848.
Mar 24, 2016Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL
Mar 24, 2016PloS one 2016; 11:e0151848
Cordeiro Olga G, Lanza François, Cupedo Tom, Ludewig Burkhard, Léon Catherine, Yagita Hideo, Rot Antal, Coles Mark C, Eckly Anita, Li Zhi, Bénézech Cécile, Romera-Hernandez Monica, Alloush Farouk, Rauber Simon, Brouard Nathalie, Chypre Mélanie, Mueller Christopher G
Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced Neuroinflammation
Cupovic J, Onder L, Gil Cruz C, Weiler E, Caviezel-Firner S, Pérez Shibayama C, Rülicke T, Bechmann I, Ludewig B. Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced Neuroinflammation. Immunity 2016; 44:622-33.
Feb 23, 2016Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced Neuroinflammation
Feb 23, 2016Immunity 2016; 44:622-33
Cupovic Jovana, Onder Lucas, Gil Cruz Cristina, Weiler Elke, Caviezel-Firner Sonja, Pérez Shibayama Christian Ivan, Rülicke Thomas, Bechmann Ingo, Ludewig Burkhard
Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility
Takeda A, Scandella E, Ludewig B, Ishii S, Aoki J, Suematsu M, Ishii M, Takeda K, Jalkanen S, Miyasaka M, Kikuta J, Hayasaka H, Kobayashi D, Aoi K, Sasaki N, Sugiura Y, Igarashi H, Tohya K, Inoue A, Hata E, Akahoshi N, Umemoto E. Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility. Elife 2016; 5
Feb 2, 2016Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility
Feb 2, 2016Elife 2016; 5
Takeda Akira, Scandella Elke, Ludewig Burkhard, Ishii Satoshi, Aoki Junken, Suematsu Makoto, Ishii Masaru, Takeda Kiyoshi, Jalkanen Sirpa, Miyasaka Masayuki, Kikuta Junichi, Hayasaka Haruko, Kobayashi Daichi, Aoi Keita, Sasaki Naoko, Sugiura Yuki, Igarashi Hidemitsu, Tohya Kazuo, Inoue Asuka, Hata Erina, Akahoshi Noriyuki, Umemoto Eiji
The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells
Mair F, Joller S, Hoeppli R, Onder L, Hahn M, Ludewig B, Waisman A, Becher B. The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells. Elife 2015; 4
Dec 5, 2015The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells
Dec 5, 2015Elife 2015; 4
Mair Florian, Joller Stefanie, Hoeppli Romy, Onder Lucas, Hahn Matthias, Ludewig Burkhard, Waisman Ari, Becher Burkhard
Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage
Bhattacharya A, Arnold I, Flatz L, Xu H, Lang P, Aderem A, Takaoka A, Superti-Furga G, Colinge J, Ludewig B, Löhning M, Baazim H, Khamina K, Panse I, Hegazy A, Deigendesch N, Kosack L, Cupovic J, Kandasamy R, Hildebrandt A, Merkler D, Kühl A, Vilagos B, Schliehe C, Bergthaler A. Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage. Immunity 2015; 43:974-86.
Nov 17, 2015Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage
Nov 17, 2015Immunity 2015; 43:974-86
Bhattacharya Anannya, Arnold Isabelle, Flatz Lukas, Xu Haifeng C, Lang Philipp A, Aderem Alan, Takaoka Akinori, Superti-Furga Giulio, Colinge Jacques, Ludewig Burkhard, Löhning Max, Baazim Hatoon, Khamina Kseniya, Panse Isabel, Hegazy Ahmed N, Deigendesch Nikolaus, Kosack Lindsay, Cupovic Jovana, Kandasamy Richard K, Hildebrandt Andrea, Merkler Doron, Kühl Anja A, Vilagos Bojan, Schliehe Christopher, Bergthaler Andreas
Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-Expressing Reticular Cells
Rodda L, Bannard O, Ludewig B, Nagasawa T, Cyster J. Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-Expressing Reticular Cells. J Immunol 2015; 195:4781-91.
Oct 9, 2015Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-Expressing Reticular Cells
Oct 9, 2015J Immunol 2015; 195:4781-91
Rodda Lauren B, Bannard Oliver, Ludewig Burkhard, Nagasawa Takashi, Cyster Jason G
Tuning up FALCs: immunological shielding in the body cavities
Pérez Shibayama C, Ludewig B. Tuning up FALCs: immunological shielding in the body cavities. Nat Immunol 2015; 16:796-8.
Jul 21, 2015Tuning up FALCs: immunological shielding in the body cavities
Jul 21, 2015Nat Immunol 2015; 16:796-8
Pérez Shibayama Christian Ivan, Ludewig Burkhard
Another TLO in the Wall: Education and Control of T Cells in Atherosclerotic Arteries
Onder L, Ludewig B. Another TLO in the Wall: Education and Control of T Cells in Atherosclerotic Arteries. Immunity 2015; 42:981-3.
Jun 16, 2015Another TLO in the Wall: Education and Control of T Cells in Atherosclerotic Arteries
Jun 16, 2015Immunity 2015; 42:981-3
Onder Lucas, Ludewig Burkhard
Computational Approach to 3D Modeling of the Lymph Node Geometry
Kislitsyn A, Savinkov R, Novkovic M, Onder L, Bocharov G. Computational Approach to 3D Modeling of the Lymph Node Geometry. Computation 2015; 3:222-234.
May 22, 2015Computational Approach to 3D Modeling of the Lymph Node Geometry
May 22, 2015Computation 2015; 3:222-234
Kislitsyn Alexey, Savinkov Rostislav, Novkovic Mario, Onder Lucas, Bocharov Gennady
Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction
Onder L, Waisman A, Becher B, Ledermann B, Mair F, Maier R, Bomze D, Novkovic M, Caviezel-Firner S, Cheng H, Chai Q, Scandella E, Nindl V, Ludewig B. Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction. Eur J Immunol 2015
May 14, 2015Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction
May 14, 2015Eur J Immunol 2015
Onder Lucas, Waisman Ari, Becher Burkhard, Ledermann Birgit, Mair Florian, Maier Reinhard, Bomze David, Novkovic Mario, Caviezel-Firner Sonja, Cheng Hung-Wei, Chai Qian, Scandella Elke, Nindl Veronika, Ludewig Burkhard
Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4+ T cell-dendritic cell interactions
Moalli F, Cupovic J, Thelen F, Halbherr P, Fukui Y, Narumiya S, Ludewig B, Stein J. Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4+ T cell-dendritic cell interactions. J Exp Med 2014; 211:2507-17.
Dec 8, 2014Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4+ T cell-dendritic cell interactions
Dec 8, 2014J Exp Med 2014; 211:2507-17
Moalli Federica, Cupovic Jovana, Thelen Flavian, Halbherr Pascal, Fukui Yoshinori, Narumiya Shuh, Ludewig Burkhard, Stein Jens V
The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture
Astarita J, Xia L, Mooney D, Carroll M, Weimer R, Ludewig B, Onder L, Gogineni A, Woodruff M, Kondo Y, Song K, Nieves-Bonilla J, Peck J, Darnell M, Fu J, Cremasco V, Turley S. The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture. Nat Immunol 2014; 16:75-84.
Oct 27, 2014The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture
Oct 27, 2014Nat Immunol 2014; 16:75-84
Astarita Jillian L, Xia Lijun, Mooney David J, Carroll Michael C, Weimer Robby M, Ludewig Burkhard, Onder Lucas, Gogineni Alvin, Woodruff Matthew C, Kondo Yuji, Song Kai, Nieves-Bonilla Janice M, Peck James R, Darnell Max C, Fu Jianxin, Cremasco Viviana, Turley Shannon J
HDAC1 controls CD8+ T cell homeostasis and antiviral response.
Tschismarov R, Firner S, Gil-Cruz C, Göschl L, Boucheron N, Steiner G, Matthias P, Seiser C, Ludewig B, Ellmeier W. HDAC1 controls CD8+ T cell homeostasis and antiviral response. PloS one 2014; 9:e110576.
Oct 21, 2014HDAC1 controls CD8+ T cell homeostasis and antiviral response.
Oct 21, 2014PloS one 2014; 9:e110576
Tschismarov Roland, Firner Sonja, Gil-Cruz Cristina, Göschl Lisa, Boucheron Nicole, Steiner Günter, Matthias Patrick, Seiser Christian, Ludewig Burkhard, Ellmeier Wilfried