In-hospital survival paradox in patients with sleep apnea-A nation-wide nested case-control study.

Publication

In-hospital survival paradox in patients with sleep apnea-A nation-wide nested case-control study.

Journal Paper/Review - Jul 21, 2022

Moser Maurice, Baty Florent, Brutsche Martin H, Schoch Otto D

Citation

Moser M, Baty F, Brutsche M, Schoch O. In-hospital survival paradox in patients with sleep apnea-A nation-wide nested case-control study. PloS one 2022; 17:e0271004.

Type

Journal Paper/Review (English)

Journal

PloS one 2022; 17

Publication Date

Jul 21, 2022

Issn Electronic

1932-6203

Pages

e0271004

Brief description/objective

Sleep apnea (SA) is a prevalent disorder characterized by recurrent events of nocturnal apnea originating from obstructive and/or central mechanisms. SA disrupts normal sleep and can lead to a series of complications when left untreated. SA results in intermittent hypoxia which has an impact on the cardio- and cerebrovascular system. Hospitalized patients with SA typically have a greater burden of comorbidity, a longer length of hospital stay, but may show an improvement of in-hospital mortality compared to patients without diagnosed SA. The reason for this survival benefit is controversial and we aimed to clarify this protective effect in the light of predictive factors including SA-associated comorbidities using a nation-wide hospitalization database.