Projects
Search from 1164 projects:
1164 Project(s)
I4V-MC-JAIM
Aug 12, 2020a phase 3, double-blind, multicenter study of evaluate the long-term safety and efficacy of baricitinib in patients with SLE.
Clinical Studies - Aug 12, 2020 - Aug 12, 2022
Completed
Project leader: Rubbert-Roth Andrea
Members: Peischl Riana, Bartz-Batliner Mira
SAKK 23/18 Vision I
Aug 11, 2020Neoadjuvant chemotherapy (NAC), initially indicated to downstage tumors to achieve the option of breast conserv-ing surgery, has lately become common practice in the primary treatment of breast cancer. The use of modern NAC regimens lead to a complet...
Clinical Studies - Aug 11, 2020 - Dec 18, 2024
Ongoing
SAKK 23/18 Vision I
Aug 11, 2020Neoadjuvant chemotherapy (NAC), initially indicated to downstage tumors to achieve the option of breast conserv-ing surgery, has lately become common practice in the primary treatment of breast cancer. The use of modern NAC regimens lead to a complet...
Clinical Studies - Aug 11, 2020 - Dec 18, 2024
Ongoing
Vacuum assisted biopsy Immediately before Surgery as an Intra- or pre-Operative surrogate for patient response to Neoadjuvant chemotherapy for breast cancer (VISION I) A multicenter prospective feasibility trial
Aug 11, 2020Manche Patientinnen und Patienten mit Brustkrebs erhalten vor der Tumoroperation eine Chemotherapie, um den Tumor zu verkleinern. Manchmal wirkt diese Chemotherapie so gut, dass der Tumor nach der Chemotherapie mit bildgebenden Verfahren nicht mehr n...
Clinical Studies - Aug 11, 2020 - Dec 31, 2024
Ongoing
Project leader: Strub Christine
Members: Sennhauser Andrina, Quinter Janine
PH-L19IL2TNFNMSC-04/19 A phase II study of intratumoral administration of L19IL2/L19TNF in non-melanoma skin cancer patients with presence of injectable lesions
Aug 2, 2020
Clinical Studies - Aug 2, 2020 - Jan 25, 2030
Ongoing
Project leader: Flatz Lukas
CRiPSI/CRiPSI-X: Covid-19 Risk Prediction in Swiss ICUs-Trial/Extension
Aug 1, 2020Outcome of patients with critical Covid-19 varies. We study risk of and predictors for poor outcome in adult patients with Covid-19 admitted to ICU in a multicenter study. In addition, we assess the prevalence of, risk factors for and mechanisms invo...
Clinical Studies - Aug 1, 2020 - Aug 31, 2022
Automatically Closed
Project leader: Albrich Werner
Members: Von Mering Christian, O'Mahony Liam, Cerny Andreas, Suh Noémie, El Baz Yassir, Dietrich Tobias, Fischer Tim, Felbecker Ansgar, Göhl-Freyn Kristina, Germann Nicolas, Schmid Dagmar, Kahlert Christian, Frischknecht Manuel, Filipovic Miodrag, Brutsche Martin, Pietsch Urs, Kleger Gian-Reto, Bochud Pierre-Yves
Abbvie UPHOLD P20-095 SLEERA
Aug 1, 2020Upadacitinib treatment patterns, achievement of treatment targets and maintenance of response in moderate to severe Rheumatoid Arthritis patients in real-world practice
Clinical Studies - Aug 1, 2020 - Oct 31, 2023
Automatically Closed
Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Hutz Carina Liane, Peischl Riana, Peischl Shirin, Schmiedeberg Kristin
ESSENCE Study
Aug 1, 2020
Clinical Studies - Aug 1, 2020 - Dec 31, 2029
Ongoing
Project leader: Bilz Stefan
Members: Semela David, Räss Andrea, Stillhard Roman
ETOP 15-19 ABC Lung A randomised non-comparative open label phase II trial of atezolizumab plus bevacizumab, with carboplatin-paclitaxel or pemetrexed, in EGFR-mutant non-small cell lung carci-noma with acquired resistance ABC-lung:
Jul 22, 2020Activating mutations in the epidermal growth factor recep-tor (EGFR) are identified in 15% of Non-Small Cell Lung Cancer. Despite the success of targeted treatment, ac-quired resistance and disease progression inevitably occur. A number of mechanisms...
Clinical Studies - Jul 22, 2020 - Aug 11, 2025
Ongoing
A PHASE II, MULTICENTRE, OPEN-LABEL STUDY OF CABOZANTINIB AS 2ND LINE TREATMENT IN SUBJECTS WITH UNRESECTABLE, LOCALLY ADVANCED OR METASTATIC RENAL CELL CARCINOMA WITH A CLEAR-CELL COMPONENT WHO PROGRESSED AFTER 1ST LINE TREATMENT WITH CHECKPOINT INHIBITORS
Jul 17, 2020Multizentrische Studie bei Patienten mit metastasiertem Nierenzellkarzinom nach Progredienz unter einer Erstli-nientherapie mit ICI/ICI oder ICI/TKI Kombination zur Eva-luation der Wirksamkeit und Verträglichkeit des Tyrosin-kinase Inhibitors Cabozan...
Clinical Studies - Jul 17, 2020 - Jul 17, 2022
Automatically Closed
Project leader: Rothermundt Christian
Members: Aeppli Stefanie, Fischer Stefanie, Omlin Aurelius
Observational study of the use of venetoclax in patients with chronic lymphocytic leukemia (CLL) under real-life setting in Austria,Germany and Switzerland (VeRVe)
Jul 15, 2020
Clinical Studies - Jul 15, 2020 - Dec 31, 2030
Ongoing
VeRVe: Observational study of the use of venetoclax in patients with chronic lymphocytic leukemia (CLL) under real-life setting in Austria,Germany and Switzerland (Venetoclax Real Value)
Jul 15, 2020
Clinical Studies - Jul 15, 2020 - Sep 27, 2022
Automatically Closed
Project leader: Baumann Michael
XATOC – Xarelto + Acetylsalicylic Acid
Jul 14, 2020Treatment patterns and Outcomes across the disease Continuum in patients with CAD and/or PAD The study aims to collect real-world data on treatment patterns and decision points for treatment in patients with coronary artery disease (CAD) or sym...
Clinical Studies - Jul 14, 2020 - Apr 14, 2023
Completed
Project leader: Rickli Hans
Members: Fink Karin
Cruz HBR
Jul 13, 2020Post-market registry to evaluate the safety and efficacy of the Supraflex Cruz™ sirolimus-eluting coronary stent system in the treatment of all-comer patients with coronary artery disease
Clinical Studies - Jul 13, 2020 - Dec 31, 2022
Completed
Project leader: Weilenmann Daniel
Members: Schneider Irene, Fink Karin
CAIN457Q12301
Jul 13, 2020A two-year, phase III randomized, double-blind, parallel- group, placebo- controlled trial to evaluate the safety, efficacy, and tolerability of 300 mg s.c. secukinumab versus placebo in combination with SoC therapy in patients with active lupus neph...
Clinical Studies - Jul 13, 2020 - Jul 12, 2023
Automatically Closed
Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Hutz Carina Liane, Peischl Riana, Sasselli Clelia
Protocol SAKK 11/16: Personalized and cell-based anti-tumor immunization MVX-ONCO-1 in advanced head and neck squamous cell carcinoma. A single arm, open label, multicenter phase II trial
Jul 10, 2020MVX-ONCO-1 is a form of active specific immunotherapy, a process by which the patient’s immune response to tumor cells is stimulated and/or augmented. MVX-ONCO-1 is a patient specific, cell-based, immunotherapy composed of: a. An immune-modulator (...
Clinical Studies - Jul 10, 2020 - Nov 8, 2023
Completed
Project leader: Rordorf Tamara
A Randomized, Double-blind, Adaptive, Phase II/III Study of GSK3359609 or Placebo in Combination with Pembroli-zumab for First-Line Treatment of PD-L1 Positive Recur-rent/Metastatic Head and Neck Squamous Cell Carcinoma
Jul 10, 2020The study will evaluate the efficacy of GSK3359609 in combination with pembrolizumab compared with pem-brolizumab plus placebo as a standard first-line chemo-therapy-free regimen in HNSCC. All participants will be stratified by 2 factors i) PD-L1 CPS...
Clinical Studies - Jul 10, 2020 - Jul 31, 2021
Automatically Closed
Project leader: Jörger Markus
Characterization of Patients Utilizing Complementary Medicine at a Tertiary Referral Hospital in Eastern Switzerland
Jul 7, 2020Mit der vorliegenden Studie sollen Daten von Patienten, die eine Therapie im ZIM in Anspruch genommen haben, nach demografischen und krankheits-spezifischen Charakteristika ausgewertet werden. Dies ermöglicht die Anpassung des bestehenden Angebotes a...
Clinical Studies - Jul 7, 2020 - Jul 7, 2021
Completed
Project leader: Schlaeppi Marc, Templeton Arnoud
Members: Schlegel Tiffany
Lymphopenie bei myeloproliferativen Neoplasien: Prävalenz und prognostische Bedeutung
Jul 1, 2020Eine Lymphopenie als Ausdruck einer Störung des adaptiven Immunsystems ist ein etablierter Risikofaktor bei verschiedenen Allgemein- und Tumorerkrankungen. Im Hinblick auf myeloische Neoplasien konnte im Rahmen eines Kooperationsprojektes des KSSG m...
Clinical Studies - Jul 1, 2020 - Jun 30, 2022
Automatically Closed
Project leader: Silzle Tobias
Members: Messerich Nora-Medea, Cogliatti Sergio B., Lehmann Thomas, Graf Lukas
SANTORINI
Jul 1, 2020To assess the characteristics and management of very high risk and high risk patients requiring lipid modifying therapies and the use of healthcare resources associated with current patient management strategies, particularly with respect to the prev...
Clinical Studies - Jul 1, 2020 - Jun 30, 2022
Automatically Closed
Project leader: Bilz Stefan
Members: Räss Andrea, Grillmayr Victoria