Project
Efficacy and safety of drotrecogin alfa (activated) in adult patients with septic shock
Completed ยท 2009 until 2011
Kleger Gian-Reto
Type
Clinical Studies
Range
Multicentric, KSSG as participating partner
Units
Status
Completed
Start Date
2009
End Date
2011
Financing
Others
Study Design
RCT
Keywords
sepsis, septic shock, activated protein C
Brief description/objective
Coagulation disturbances are a mayor event in severe sepsis and septic shock. Activated protein C may reduce mortality in these patients by its antiinflammatory, antithrombotic and antifibrinolytic effect. However, bleeding complications are more frequent.