Projects
Search from 1138 projects:
1138 Project(s)
Colchicine in Patients at Cardiac Risk undergoing Major Non-Cardiac Surgery: prospective, randomized, triple-blinded, placebo-controlled, multi-centre study
Sep 30, 2027
Clinical Studies - Sep 30, 2027 - Sep 30, 2027
Scheduled
Project leader: Filipovic Miodrag, Yurttas Timur
Members: Klein Carsten, Keller Mirja
Novel screening assay for novel psychoactive substances
May 1, 2024Consumption of so-called novel psychoactive substances (e.g. “synthetic opioids” and “synthetic cannabinoids”) is a growing global health threat. Due to the rapid market dynamics of the new drugs of abuse market current analytical methods cannot keep...
Fundamental Research - May 1, 2024 - Apr 30, 2025
Scheduled
Project leader: Moosmann Björn
Point Prevalence of Antibiotic Resistance in Helicobacter pylori in St. Gallen: An Observational Pilot Trial
May 1, 2024Evaluation der Antibiotika-Resistenz von Helicobacter pylori Magen und Überprüfung der Konsistenz von Resistenzdaten aus dem Stuhl und aus Magenbiopsien
Clinical Studies - May 1, 2024 - Jun 30, 2025
Scheduled
Project leader: Kueres-Wiese Alexander
Members: Kuster Stefan, Frei Nicola Fabian, Borovicka Jan
A PHASE 3, OPEN-LABEL, RANDOMIZED STUDY TO COMPARE THE EFFICACY AND SAFETY OF ODRONEXTAMAB (REGN1979), AN ANTICD20 X ANTI-CD3 BISPECIFIC ANTIBODY, VERSUS INVESTIGATOR’S CHOICE IN PREVIOUSLY UNTREATED PARTICIPANTS WITH FOLLICULAR LYMPHOMA (OLYMPIA-1)
Apr 18, 2024
Clinical Studies - Apr 18, 2024 - Dec 31, 2028
Ongoing
Project leader: Hitz Felicitas
Members: Bürki Ramona, Quinter Janine
A randomized, open-label Phase II/III efficacy and safety study of atezolizumab in combination with FLOT versus FLOT alone in patients with gastric cancer and adenocarcinoma of the oesophago-gastric junction and high immune responsiveness (MO30039/MO43340)– The DANTE Trial A Trial of AIO in collaboration with SAKK
Apr 17, 2024
Clinical Studies - Apr 17, 2024 - Dec 31, 2028
Ongoing
Project leader: Weisshaupt Christian
Members: Müller Fiona, Kehl Jeanine
Drainageflüssigkeitssensor zur Früherkennung von Anastomosenlecks
Apr 3, 2024Die Studie hat zum Ziel, Eigenschaften von abdominaler Drainageflüssigkeit von Patientinnen/Patienten, die sich einer Pankreas-, Ösophagus- oder Rektumoperation unterzogen haben, zu charakterisieren. In einem Folgeschritt soll die Korrelation einer S...
Clinical Studies - Apr 3, 2024 - Mar 31, 2025
Ongoing
Project leader: Tarantino Ignazio
Members: Seiler Edith, Matzinger Marlene
An Open-label, Dose Escalation, Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of TAK-676 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced or Metastatic Solid Tumors
Mar 25, 2024
Clinical Studies - Mar 25, 2024 - Dec 31, 2028
Ongoing
Project leader: Hess Dagmar
Members: Hutter Franziska, Quinter Janine
CELIA (Phase 2)
Mar 1, 2024A Study to Learn About the Safety of BIIB080 and Whether it Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age
Clinical Studies - Mar 1, 2024 - Dec 31, 2026
Ongoing
Project leader: Felbecker Ansgar
Members: Göhl-Freyn Kristina
Large language models for the identification of etiotypes in Chronic Obstructive Lung Diseases
Mar 1, 2024Recent guidelines proposed new taxonomic classifications for COPD, so-called etiotypes, which have clinical relevance for management and treatment of patients. This project hypothesizes that information extracted from patients' electronic health reco...
Fundamental Research - Mar 1, 2024 - Feb 28, 2025
Ongoing
Project leader: Baty Florent
Members: Brutsche Martin, Albrich Werner, Hastings Janna, Kozu Kei, Toromanovic Tim
Memory Clinic Cohort Study
Mar 1, 2024Dementia is a clinical syndrome defined by a progressive cognitive decline interfering with a person's daily life and activities which is caused by a group of heterogenous neurodegenerative and neurovascular diseases which often overlap. Since patho...
Clinical Studies - Mar 1, 2024 - Dec 31, 2040
Ongoing
Project leader: Schneider Thomas, Felbecker Ansgar
Members: Göhl-Freyn Kristina, Schilg-Hafer Lenka
Combination of Abemaciclib and endocrine therapy in hormone receptor positive HER2 negative locally advanced or metastatic breast cancer with focus on digital side effect management. The MINERVA Trial – A phase IV Trial
Feb 29, 2024In der Minerva-Studie erhalten die Patientinnen das Medikament Abemaciclib entsprechend der Zulassung in Kombination mit einem Aromatasehemmer oder Fulvestrant als endokrine Therapie. Die Wahl der passenden endokrinen Therapie trifft der Prüfarzt/ di...
Clinical Studies - Feb 29, 2024 - Dec 31, 2028
Ongoing
Project leader: Huober Jens
Members: Radovanovic Suzana, Frehner Jan
A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel, Multicenter Study to Evaluate the Safety and Efficacy of ALXN1720 in Adults with Generalized Myasthenia Gravis
Feb 1, 2024
Clinical Studies - Feb 1, 2024 - Apr 4, 2027
Ongoing
Members: Neuwirth Christoph
Phase 2/3 Randomized Study of Tebentafusp as Monotherapy and in Combination with Pembrolizumab Versus Investigator’s Choice in HLA-A*02:01-positive Participants with Previously Treated Advanced Melanoma (TEBE-AM)
Jan 26, 2024
Clinical Studies - Jan 26, 2024 - Dec 31, 2027
Ongoing
Project leader: Aeppli Stefanie
Members: Scherrer Julia, Quinter Janine
Comparison of discordant baseline imaging findings, reassessment of binary ischemic core evaluation and hypodensity mapping for functional outcome prediction in middle cerebral artery ischemic stroke using ASPECTS
Jan 1, 2024All subprojects focus on expanding the understanding of the emerging trend towards ubiquitously accessible and technically simpler imaging selection criteria for endovascular treatment based on native CT brainimaging in patients with acute ischemic s...
Clinical Studies - Jan 1, 2024 - Jan 1, 2026
Scheduled
Project leader: Dittrich Tolga
Prevalence of serous tubal intraepthelial carcinoma and signature lesions in fallopian tube specimens and PAP smear samples of breast and ovarian cancer patients
Dec 31, 2023«Proof-of-Concept Studie. Ziel ist das Entwickeln einer Methode zur Früherkennung von hochgradige seröse Ovarialkarzinom, insbesondere bei BRCA-mutierten Frauen. Hochgradiges seröses Ovarialkarzinom ist der häufigste Subtyp von Eierstockkrebs mit...
Fundamental Research - Dec 31, 2023 - Dec 31, 2024
Ongoing
Project leader: Hornung René
Members: Nemes Constanze, Su Elena
A single-arm phase II trial of the addition of niraparib to anti-PD-L1 antibody maintenance in patients with SLFN11-positive, extensive-disease small cell lung cancer.
Dec 21, 2023
Clinical Studies - Dec 21, 2023 - Dec 31, 2027
Ongoing
Project leader: Jörger Markus
Members: Quinter Janine, Radovanovic Suzana
OASIS – Optimierung der Antibiotikanutzung im stationären Setting durch Interprofessionelles Stewardship
Dec 1, 2023Zur Optimierung des Antibiotikaverbrauchs wurde am Kantonsspital St.Gallen ein Antimicrobial Stewardship Programm (ASP) eingeführt. Für die erfolgreiche Umsetzung braucht es die aktive Einbindung aller beteiligten Fachpersonen über den gesamten Verso...
Healthcare Research - Dec 1, 2023 - Jun 30, 2024
Ongoing
Project leader: Künzler-Heule Patrizia
Members: Kohler Philipp, Kuster Stefan, Ledergerber Katrin, Flury Domenica, Schoop Barbara, Nicca D
Carity Study
Dec 1, 2023CARITY: A targeted approach to ensuring CARe and ActivITY persistence in mid- to older-age persons during and after cardiac rehabilitation following a cardiovascular event or intervention
Clinical Studies - Dec 1, 2023 - Feb 1, 2025
Ongoing
Project leader: Buser Marc
Members: Vetsch Susanne
A Phase III, Randomized, Open-Label, Multicenter, Global Study of Volrustomig (MEDI5752) in Combination with Carboplatin plus Pemetrexed Versus Platinum plus Pemetrexed or Nivolumab plus Ipilimumab in Participants with Unresectable Pleural Mesothelioma (eVOLVE-Meso)
Nov 17, 2023Forscher suchen nach einer besseren Möglichkeit, fortgeschrittenes Pleuramesotheliom zu behandeln. Pleuramesotheliom ist eine Krebsart, die die Lungenschleimhaut befällt. Fortgeschritten bedeutet in der Regel, dass der Krebs nicht operativ behandelt...
Clinical Studies - Nov 17, 2023 - Dec 31, 2028
Ongoing
Project leader: Früh Martin
Members: Demmer-Steingruber Ruth, Quinter Janine
A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC and Lenalidomide (Tec-DR) versus Daratumumab SC, Lenalidomide, and Dexamethasone (DRd) in Participants with Newly Diagnosed Multiple Myeloma Who are Either Ineligible or not Intended for Autologous Stem Cell Transplant as Initial Therapy
Nov 3, 2023
Clinical Studies - Nov 3, 2023 - Dec 1, 2028
Ongoing
Project leader: Baumann Michael
Members: Harder Anja, Quinter Janine