Dr. med. et phil. nat. David Semela
chief of service
Gastroenterology/Hepatology · Dept. I
STAR LIGHT Study: XBB.1.5 COVID-19 mRNA Vaccines Boost Systemic but Not Mucosal Immunity Against the SARS-CoV-2 JN.1 Variant in Patients with Chronic Liver Disease.
Woelfel S, Junker D, Bergamin I, Meyer-Herbon P, Stillhard R, Graf N, Leinenkugel G, Dütschler J, König M, Häuptle R, Zwyssig S, Krieger-Grübel C, Truniger S, Koller S, Metzger-Peter K, Frei N, Genetics And Observational Subarachnoid Haemorrhage Gosh Study Investigators, Albrich W, Friedrich M, Bernsmeier C, Niess J, Korte W, Bürgi J, Dulovic A, Schneiderhan-Marra N, Semela D, Brand S. STAR LIGHT Study: XBB.1.5 COVID-19 mRNA Vaccines Boost Systemic but Not Mucosal Immunity Against the SARS-CoV-2 JN.1 Variant in Patients with Chronic Liver Disease. Vaccines (Basel) 2024; 12
Oct 31, 2024STAR LIGHT Study: XBB.1.5 COVID-19 mRNA Vaccines Boost Systemic but Not Mucosal Immunity Against the SARS-CoV-2 JN.1 Variant in Patients with Chronic Liver Disease.
Oct 31, 2024Vaccines (Basel) 2024; 12
Woelfel Simon, Junker Daniel, Bergamin Irina, Meyer-Herbon Pamela, Stillhard Roman, Graf Nicole, Leinenkugel Georg, Dütschler Joel, König Marius, Häuptle Rahel, Zwyssig Sarah, Krieger-Grübel Claudia, Truniger Samuel, Koller Seraina, Metzger-Peter Katline, Frei Nicola Fabian, Genetics And Observational Subarachnoid Haemorrhage Gosh Study Investigators, Albrich Werner, Friedrich Matthias, Bernsmeier Christine, Niess Jan-Hendrik, Korte Wolfgang C, Bürgi Justus J, Dulovic Alex, Schneiderhan-Marra Nicole, Semela David, Brand Stephan
Effect of Direct Acting Antiviral Drugs on the Occurrence and Recurrence of Intra- and Extra-Hepatic Malignancies in Patients with Chronic Hepatitis C Virus Infection.
Radu P, Becchetti C, Schropp J, Schmid P, Künzler-Heule P, Mertens J, Moradpour D, Mullhaupt B, Semela D, Negro F, Heim M, Clerc O, Roelens M, Keiser O, Berzigotti A, Swiss Hepatitis C Cohort Study. Effect of Direct Acting Antiviral Drugs on the Occurrence and Recurrence of Intra- and Extra-Hepatic Malignancies in Patients with Chronic Hepatitis C Virus Infection. Cancers (Basel) 2024; 16
Jul 18, 2024Effect of Direct Acting Antiviral Drugs on the Occurrence and Recurrence of Intra- and Extra-Hepatic Malignancies in Patients with Chronic Hepatitis C Virus Infection.
Jul 18, 2024Cancers (Basel) 2024; 16
Radu Pompilia, Becchetti Chiara, Schropp Jonas, Schmid Patrick, Künzler-Heule Patrizia, Mertens Joachim C, Moradpour Darius, Mullhaupt Beat, Semela David, Negro Francesco, Heim Markus H, Clerc Olivier F, Roelens Maroussia, Keiser Olivia, Berzigotti Annalisa, Swiss Hepatitis C Cohort Study
Real-life experience of chronic hepatitis C treatment in Switzerland: a retrospective analysis.
Moschouri E, Salemme G, Baserga A, Cerny A, Deibel A, Muellhaupt B, Meier M, Bernsmeier C, Ongaro M, Negro F, Grosjean M, Clerc O, Künzler-Heule P, Semela D, Hobi G, Stickel F, Mathieu A, Mdawar-Bailly E, Faouzi M, Moradpour D, Fraga M. Real-life experience of chronic hepatitis C treatment in Switzerland: a retrospective analysis. Swiss Med Wkly 2024; 154:3698.
Jun 24, 2024Real-life experience of chronic hepatitis C treatment in Switzerland: a retrospective analysis.
Jun 24, 2024Swiss Med Wkly 2024; 154:3698
Moschouri Eleni, Salemme Gloria, Baserga Adriana, Cerny Andreas, Deibel Ansgar, Muellhaupt Beat, Meier Marie-Anne, Bernsmeier Christine, Ongaro Marie, Negro Francesco, Grosjean Marielle, Clerc Olivier F, Künzler-Heule Patrizia, Semela David, Hobi Gabriel, Stickel Felix, Mathieu Adeline, Mdawar-Bailly Elise, Faouzi Mohamed, Moradpour Darius, Fraga Montserrat
Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E.
Saadat A, Gouttenoire J, Ripellino P, Semela D, Amar S, Frey B, Fontana S, Mdawar-Bailly E, Moradpour D, Fellay J, Fraga M, HEV Human Genetics Collaborators. Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E. Hepatology 2023
Dec 8, 2023Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E.
Dec 8, 2023Hepatology 2023
Saadat Ali, Gouttenoire Jérôme, Ripellino Paolo, Semela David, Amar Soraya, Frey Beat M, Fontana Stefano, Mdawar-Bailly Elise, Moradpour Darius, Fellay Jacques, Fraga Montserrat, HEV Human Genetics Collaborators
Antithrombotic therapy and assessment for bleeding diathesis in elective gastrointestinal endoscopy - Expert Opinion Statement on behalf of the Swiss Society of Gastroenterology.
Wiegand N, Geyer M, Lollo G, Wuillemin W, Aepli P, Frei R, Godat S, Manz M, Seewald S, The F, Wiest R, Borovicka J, Brand S, Buyse S, Degen L, Ehmann T, Riniker F, Riva D, Semela D, Truninger K, Utzinger E, Vonlaufen A. Antithrombotic therapy and assessment for bleeding diathesis in elective gastrointestinal endoscopy - Expert Opinion Statement on behalf of the Swiss Society of Gastroenterology. Praxis (Bern 1994) 2023; 112:635-641.
Dec 1, 2023Antithrombotic therapy and assessment for bleeding diathesis in elective gastrointestinal endoscopy - Expert Opinion Statement on behalf of the Swiss Society of Gastroenterology.
Dec 1, 2023Praxis (Bern 1994) 2023; 112:635-641
Wiegand Nico, Geyer Martin, Lollo Gianluca, Wuillemin W A, Aepli Patrick, Frei Remus, Godat Sébastien, Manz Michael, Seewald Stefan, The Frans Olivier, Wiest Reiner, Borovicka Jan, Brand Stephan, Buyse Sophie, Degen Lukas, Ehmann Tobias, Riniker Florian, Riva Daniele, Semela David, Truninger Kaspar, Utzinger Ellen, Vonlaufen Alain
Ultrasound Doppler technique for the diagnosis of focal nodular hyperplasia - case series and systematic review.
Sawatzki M, Burkart T, Baumeler S, Semela D, Dong Y, Jenssen C, Srivastava D, Dietrich C. Ultrasound Doppler technique for the diagnosis of focal nodular hyperplasia - case series and systematic review. Med Ultrason 2023
Nov 19, 2023Ultrasound Doppler technique for the diagnosis of focal nodular hyperplasia - case series and systematic review.
Nov 19, 2023Med Ultrason 2023
Sawatzki Mikael, Burkart Thomas, Baumeler Stephan, Semela David, Dong Yi, Jenssen Christian, Srivastava David, Dietrich Christoph F
Ultrasound Doppler technique for the diagnosis of focal nodular hyperplasia – case series and systematic review
Sawatzki M, Baumeler S, Semela D. Ultrasound Doppler technique for the diagnosis of focal nodular hyperplasia – case series and systematic review. Med Ultrason 2023; Online first:1-11.
Nov 1, 2023Ultrasound Doppler technique for the diagnosis of focal nodular hyperplasia – case series and systematic review
Nov 1, 2023Med Ultrason 2023; Online first:1-11
Sawatzki Mikael, Baumeler Stephan, Semela David
Management of biliary obstruction in patients with newly diagnosed alveolar echinococcosis: a Swiss retrospective cohort study.
Mueller S, Ghafoor S, Meyer Zu Schwabedissen C, Grimm F, Murray F, Husmann L, Stanek N, Deplazes P, Schlag C, Kremer A, Gubler C, Reiner C, Semela D, Muellhaupt B, Deibel A. Management of biliary obstruction in patients with newly diagnosed alveolar echinococcosis: a Swiss retrospective cohort study. Swiss Med Wkly 2023; 153:40116.
Oct 6, 2023Management of biliary obstruction in patients with newly diagnosed alveolar echinococcosis: a Swiss retrospective cohort study.
Oct 6, 2023Swiss Med Wkly 2023; 153:40116
Mueller Sandra, Ghafoor Soleen, Meyer Zu Schwabedissen Cordula, Grimm Felix, Murray Fritz Ruprecht, Husmann Lars, Stanek Nadine, Deplazes Peter, Schlag Christoph, Kremer Andreas E, Gubler Christoph, Reiner Caecilia S, Semela David, Muellhaupt Beat, Deibel Ansgar
Assessment of focal liver lesions in non-cirrhotic liver – expert opinion statement by the Swiss Association for the Study of the Liver and the Swiss Society of Gastroenterology
Sawatzki M, Husarik D, Semela D. Assessment of focal liver lesions in non-cirrhotic liver – expert opinion statement by the Swiss Association for the Study of the Liver and the Swiss Society of Gastroenterology. Swiss Med Wkly 2023; 153:1-19.
Sep 12, 2023Assessment of focal liver lesions in non-cirrhotic liver – expert opinion statement by the Swiss Association for the Study of the Liver and the Swiss Society of Gastroenterology
Sep 12, 2023Swiss Med Wkly 2023; 153:1-19
Sawatzki Mikael, Husarik Daniela B., Semela David
Epidemiology, clinical features and management of autoimmune hepatitis in Switzerland: a retrospective and prospective cohort study.
Ludz C, Stirnimann G, Semela D, Mertens J, Kremer A, Filipowicz Sinnreich M, Sokollik C, Bernsmeier C, Bresson-Hadni S, McLin V, Rock N, Braegger C, Posovszky C, Müller P, Cremer M, De Gottardi A, Galante A, Furlano R, Righini-Grunder F, Becker B, Böhm S, Heyland K, Nydegger A, Limoni C, Vergani D, Mieli-Vergani G, Di Bartolomeo C, Cerny A, Terziroli Beretta-Piccoli B. Epidemiology, clinical features and management of autoimmune hepatitis in Switzerland: a retrospective and prospective cohort study. Swiss Med Wkly 2023; 153:40102.
Aug 31, 2023Epidemiology, clinical features and management of autoimmune hepatitis in Switzerland: a retrospective and prospective cohort study.
Aug 31, 2023Swiss Med Wkly 2023; 153:40102
Ludz Christine, Stirnimann Guido, Semela David, Mertens Joachim C, Kremer Andreas E, Filipowicz Sinnreich Magdalena, Sokollik Christiane, Bernsmeier Christine, Bresson-Hadni Solange, McLin Valérie, Rock Nathalie, Braegger Christian P, Posovszky Carsten, Müller Pascal, Cremer Matthias, De Gottardi Andrea, Galante Antonio, Furlano Raoul, Righini-Grunder Franziska, Becker Björn, Böhm Stephan, Heyland Klaas, Nydegger Andreas, Limoni Costanzo, Vergani Diego, Mieli-Vergani Giorgina, Di Bartolomeo Claudia, Cerny Andreas, Terziroli Beretta-Piccoli Benedetta
CME: Ambulantes Management von Patientinnen und Patienten mit Leberzirrhose
Deuschle F, Semela D, Henz S. CME: Ambulantes Management von Patientinnen und Patienten mit Leberzirrhose. Praxis (Bern 1994) 2023; 112:373-380-380.
Jun 7, 2023CME: Ambulantes Management von Patientinnen und Patienten mit Leberzirrhose
Jun 7, 2023Praxis (Bern 1994) 2023; 112:373-380-380
Deuschle Florian, Semela David, Henz Samuel
The current and future burden of hepatitis B in Switzerland: a modelling study.
Negro F, Muellhaupt B, Semela D, Blach S, Bruggmann P, De Gottardi A, Dufour J, Fraga M, Galante A, Razavi H, Vieira Barbosa J, Razavi-Shearer D. The current and future burden of hepatitis B in Switzerland: a modelling study. Swiss Med Wkly 2023; 153:40086.
Jun 5, 2023The current and future burden of hepatitis B in Switzerland: a modelling study.
Jun 5, 2023Swiss Med Wkly 2023; 153:40086
Negro Francesco, Muellhaupt Beat, Semela David, Blach Sarah, Bruggmann Philipp, De Gottardi Andrea, Dufour Jean-François, Fraga Montserrat, Galante Antonio, Razavi Homie, Vieira Barbosa Joana, Razavi-Shearer Devin
AXL expression on homeostatic resident liver macrophages is reduced in cirrhosis following GAS6 production by hepatic stellate cells.
Pop O, Geng A, Flint E, Singanayagam A, Ercan C, Possamai L, Patel V, Künzler-Heule P, Meier M, Soysal S, Hruz P, Kollmar O, Tatham K, Ward J, Mullhaupt B, Weber A, Wendon J, Niess J, Heim M, Semela D, Weston C, Antoniades C, Terracciano L, Triantafyllou E, Brenig R, Bernsmeier C. AXL expression on homeostatic resident liver macrophages is reduced in cirrhosis following GAS6 production by hepatic stellate cells. Cell Mol Gastroenterol Hepatol 2023
Mar 31, 2023AXL expression on homeostatic resident liver macrophages is reduced in cirrhosis following GAS6 production by hepatic stellate cells.
Mar 31, 2023Cell Mol Gastroenterol Hepatol 2023
Pop Oltin-Tiberiu, Geng Anne, Flint Emilio, Singanayagam Arjuna, Ercan Caner, Possamai Lucia A, Patel Vishal C, Künzler-Heule Patrizia, Meier Marie-Anne, Soysal Savas D, Hruz Petr, Kollmar Otto, Tatham Kate C, Ward Josie K, Mullhaupt Beat, Weber Achim, Wendon Julia, Niess Jan Hendrik, Heim Markus, Semela David, Weston Christopher J, Antoniades Charalambos G, Terracciano Luigi, Triantafyllou Evangelos, Brenig Robert, Bernsmeier Christine
miR-579-3p Controls Hepatocellular Carcinoma Formation by Regulating the Phosphoinositide 3-Kinase-Protein Kinase B Pathway in Chronically Inflamed Liver.
Quintavalle C, Meyer-Schaller N, Roessler S, Calabrese D, Marone R, Riedl T, Picco-Rey S, Panagiotou O, Uzun S, Piscuoglio S, Boldanova T, Bian C, Semela D, Jochum W, Cathomas G, Mertz K, Diebold J, Mazzucchelli L, Koelzer V, Weber A, Decaens T, Terracciano L, Heikenwalder M, Hoshida Y, Andersen J, Thorgeirsson S, Matter M. miR-579-3p Controls Hepatocellular Carcinoma Formation by Regulating the Phosphoinositide 3-Kinase-Protein Kinase B Pathway in Chronically Inflamed Liver. Hepatol Commun 2022; 6:1467-1481.
Feb 8, 2022miR-579-3p Controls Hepatocellular Carcinoma Formation by Regulating the Phosphoinositide 3-Kinase-Protein Kinase B Pathway in Chronically Inflamed Liver.
Feb 8, 2022Hepatol Commun 2022; 6:1467-1481
Quintavalle Cristina, Meyer-Schaller Nathalie, Roessler Stephanie, Calabrese Diego, Marone Romina, Riedl Tobias, Picco-Rey Silvia, Panagiotou Orestis A, Uzun Sarp, Piscuoglio Salvatore, Boldanova Tuyana, Bian Chaoran B, Semela David, Jochum Wolfram, Cathomas Gieri, Mertz Kirsten D, Diebold Joachim, Mazzucchelli Luca, Koelzer Viktor H, Weber Achim, Decaens Thomas, Terracciano Luigi M, Heikenwalder Mathias, Hoshida Yujin, Andersen Jesper B, Thorgeirsson Snorri S, Matter Matthias S
Presence of autoantibodies in serum does not impact the occurrence of immune checkpoint inhibitor-induced hepatitis in a prospective cohort of cancer patients.
Purde M, Niederer R, Wagner N, Diem S, Berner F, Hasan Ali O, Hillmann D, Bergamin I, Jörger M, Risch M, Niederhauser C, Lenz T, Früh M, Risch L, Semela D, Flatz L. Presence of autoantibodies in serum does not impact the occurrence of immune checkpoint inhibitor-induced hepatitis in a prospective cohort of cancer patients. J Cancer Res Clin Oncol 2021; 148:647-656.
Dec 7, 2021Presence of autoantibodies in serum does not impact the occurrence of immune checkpoint inhibitor-induced hepatitis in a prospective cohort of cancer patients.
Dec 7, 2021J Cancer Res Clin Oncol 2021; 148:647-656
Purde Mette-Triin, Niederer Rebekka, Wagner Nikolaus, Diem Stefan, Berner Fiamma, Hasan Ali Omar, Hillmann Dorothea, Bergamin Irina, Jörger Markus, Risch Martin, Niederhauser Christoph, Lenz Tobias L, Früh Martin, Risch Lorenz, Semela David, Flatz Lukas
Klinisches Management von Patienten mit Leberzirrhose
Bergamin I, Meyer-Herbon P, Künzler-Heule P, Semela D. Klinisches Management von Patienten mit Leberzirrhose. Schweiz. Gastroenterol. 2021
Dec 3, 2021Klinisches Management von Patienten mit Leberzirrhose
Dec 3, 2021Schweiz. Gastroenterol. 2021
Bergamin Irina, Meyer-Herbon Pamela, Künzler-Heule Patrizia, Semela David
HCV disease burden and population segments in Switzerland
Bihl F, Semmo N, Semela D, Scheidegger C, Razavi H, Negro F, Mullhaupt B, Lavanchy D, Dufour J, Castro Batänjer E, Bruggmann P, Blach S. HCV disease burden and population segments in Switzerland. Liver Int 2021
Nov 27, 2021HCV disease burden and population segments in Switzerland
Nov 27, 2021Liver Int 2021
Bihl Florian, Semmo Nasser, Semela David, Scheidegger Claude, Razavi Homie, Negro Francesco, Mullhaupt Beat, Lavanchy Daniel, Dufour Jean-François, Castro Batänjer Erika, Bruggmann Philip, Blach Sarah
Impact of propofol sedation on the diagnostic accuracy of hepatic venous pressure gradient measurements in patients with cirrhosis
Ebrahimi F, Semela D, Heim M. Impact of propofol sedation on the diagnostic accuracy of hepatic venous pressure gradient measurements in patients with cirrhosis. Hepatol Int 2021
Oct 26, 2021Impact of propofol sedation on the diagnostic accuracy of hepatic venous pressure gradient measurements in patients with cirrhosis
Oct 26, 2021Hepatol Int 2021
Ebrahimi Fahim, Semela David, Heim Markus
Autochthonous hepatitis E as a cause of acute-on-chronic liver failure and death: histopathology can be misleading but transaminases may provide a clue
Vieira Barbosa J, Moradpour D, Weber A, Lenggenhager D, Sempoux C, Mathurin P, Louvet A, Artru F, Gouttenoire J, Neuweiler J, Cathomas G, Montani M, Semela D, Filipowicz Sinnreich M, Brunner F, Mullhaupt B, Fraga M. Autochthonous hepatitis E as a cause of acute-on-chronic liver failure and death: histopathology can be misleading but transaminases may provide a clue. Swiss Med Wkly 2021; 151:w20502.
May 4, 2021Autochthonous hepatitis E as a cause of acute-on-chronic liver failure and death: histopathology can be misleading but transaminases may provide a clue
May 4, 2021Swiss Med Wkly 2021; 151:w20502
Vieira Barbosa Joana, Moradpour Darius, Weber Achim, Lenggenhager Daniela, Sempoux Christine, Mathurin Philippe, Louvet Alexandre, Artru Florent, Gouttenoire Jérôme, Neuweiler Jörg, Cathomas Gieri, Montani Matteo, Semela David, Filipowicz Sinnreich Magdalena, Brunner Felix, Mullhaupt Beat, Fraga Montserrat
Empfehlungen für die Nachsorge von Patientinnen/Patienten mit ausgeheilter Hepatitis C
Bobzin C, Semmo N, Semela D, Scheidegger C, Rauch A, Negro F, Moradpour D, Mäschli B, Lavanchy D, Künzler-Heule P, Keiser O, Fraga Christinet M, Cerny A, Bruggmann P, Bösiger C, Thurnheer M. Empfehlungen für die Nachsorge von Patientinnen/Patienten mit ausgeheilter Hepatitis C. Swiss Medical Forum 2021; 21:184-186.
Mar 17, 2021Empfehlungen für die Nachsorge von Patientinnen/Patienten mit ausgeheilter Hepatitis C
Mar 17, 2021Swiss Medical Forum 2021; 21:184-186
Bobzin Carina, Semmo Nasser, Semela David, Scheidegger Claude, Rauch Andri, Negro Francesco, Moradpour Darius, Mäschli Bettina, Lavanchy D, Künzler-Heule Patrizia, Keiser Olivia, Fraga Christinet Montserrat, Cerny Andreas, Bruggmann Philip, Bösiger Christophe, Thurnheer Maria Christine