Julia Diegelmann
Identification of IL-27 as a novel regulator of major histocompatibility complex class I and class II expression, antigen presentation, and processing in intestinal epithelial cells.
Diegelmann J, Brand S. Identification of IL-27 as a novel regulator of major histocompatibility complex class I and class II expression, antigen presentation, and processing in intestinal epithelial cells. Front Immunol 2023; 14:1226809.
Sep 25, 2023Identification of IL-27 as a novel regulator of major histocompatibility complex class I and class II expression, antigen presentation, and processing in intestinal epithelial cells.
Sep 25, 2023Front Immunol 2023; 14:1226809
Diegelmann Julia, Brand Stephan
Iron Deficiency in Inflammatory Bowel Disease Is Associated With Low Levels of Vitamin D Modulating Serum Hepcidin and Intestinal Ceruloplasmin Expression.
Stallhofer J, Veith L, Diegelmann J, Probst P, Brand S, Schnitzler F, Olszak T, Török H, Mayerle J, Stallmach A, Beigel F. Iron Deficiency in Inflammatory Bowel Disease Is Associated With Low Levels of Vitamin D Modulating Serum Hepcidin and Intestinal Ceruloplasmin Expression. Clin Transl Gastroenterol 2022; 13:e00450.
Jan 13, 2022Iron Deficiency in Inflammatory Bowel Disease Is Associated With Low Levels of Vitamin D Modulating Serum Hepcidin and Intestinal Ceruloplasmin Expression.
Jan 13, 2022Clin Transl Gastroenterol 2022; 13:e00450
Stallhofer Johannes, Veith Lisa, Diegelmann Julia, Probst Philipp, Brand Stephan, Schnitzler Fabian, Olszak Torsten, Török Helga P, Mayerle Julia, Stallmach Andreas, Beigel Florian
Development of a uniform, very aggressive disease phenotype in all homozygous carriers of the NOD2 mutation p.Leu1007fsX1008 with Crohn's disease and active smoking status resulting in ileal stenosis requiring surgery.
Schnitzler F, Friedrich M, Angelberger M, Diegelmann J, Stallhofer J, Wolf C, Dütschler J, Truniger S, Olszak T, Beigel F, Tillack C, Lohse P, Brand S. Development of a uniform, very aggressive disease phenotype in all homozygous carriers of the NOD2 mutation p.Leu1007fsX1008 with Crohn's disease and active smoking status resulting in ileal stenosis requiring surgery. PloS one 2020; 15:e0236421.
Jul 27, 2020Development of a uniform, very aggressive disease phenotype in all homozygous carriers of the NOD2 mutation p.Leu1007fsX1008 with Crohn's disease and active smoking status resulting in ileal stenosis requiring surgery.
Jul 27, 2020PloS one 2020; 15:e0236421
Schnitzler Fabian, Friedrich Matthias, Angelberger Marianne, Diegelmann Julia, Stallhofer Johannes, Wolf Christiane, Dütschler Joel, Truniger Samuel, Olszak Torsten, Beigel Florian, Tillack Cornelia, Lohse Peter, Brand Stephan
The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A>C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations
Schnitzler F, Lohse P, Glas J, Göke B, Beigel F, Tillack C, Olszak T, Diegelmann J, Angelberger M, Stallhofer J, Wolf C, Friedrich M, Brand S. The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A>C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations. PloS one 2015; 10:e0116044.
Jul 6, 2015The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A>C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations
Jul 6, 2015PloS one 2015; 10:e0116044
Schnitzler Fabian, Lohse Peter, Glas Jürgen, Göke Burkhard, Beigel Florian, Tillack Cornelia, Olszak Torsten, Diegelmann Julia, Angelberger Marianne, Stallhofer Johannes, Wolf Christiane, Friedrich Matthias, Brand Stephan
The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067
Schnitzler F, Lohse P, Glas J, Göke B, Stallhofer J, Tillack C, Beigel F, Olszak T, Diegelmann J, Angelberger M, Wolf C, Friedrich M, Brand S. The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067. PloS one 2014; 9:e108503.
Nov 3, 2014The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067
Nov 3, 2014PloS one 2014; 9:e108503
Schnitzler Fabian, Lohse Peter, Glas Jürgen, Göke Burkhard, Stallhofer Johannes, Tillack Cornelia, Beigel Florian, Olszak Torsten, Diegelmann Julia, Angelberger Marianne, Wolf Christiane, Friedrich Matthias, Brand Stephan
IL-17A alone weakly affects the transcriptome of intestinal epithelial cells but strongly modulates the TNF-α-induced expression of inflammatory mediators and inflammatory bowel disease susceptibility genes
Friedrich M, Diegelmann J, Beigel F, Brand S. IL-17A alone weakly affects the transcriptome of intestinal epithelial cells but strongly modulates the TNF-α-induced expression of inflammatory mediators and inflammatory bowel disease susceptibility genes. Inflamm Bowel Dis 2014; 20:1502-15.
Sep 1, 2014IL-17A alone weakly affects the transcriptome of intestinal epithelial cells but strongly modulates the TNF-α-induced expression of inflammatory mediators and inflammatory bowel disease susceptibility genes
Sep 1, 2014Inflamm Bowel Dis 2014; 20:1502-15
Friedrich Matthias, Diegelmann Julia, Beigel Florian, Brand Stephan
Oncostatin M mediates STAT3-dependent intestinal epithelial restitution via increased cell proliferation, decreased apoptosis and upregulation of SERPIN family members
Beigel F, Friedrich M, Probst C, Sotlar K, Göke B, Diegelmann J, Brand S. Oncostatin M mediates STAT3-dependent intestinal epithelial restitution via increased cell proliferation, decreased apoptosis and upregulation of SERPIN family members. PloS one 2014; 9:e93498.
Apr 7, 2014Oncostatin M mediates STAT3-dependent intestinal epithelial restitution via increased cell proliferation, decreased apoptosis and upregulation of SERPIN family members
Apr 7, 2014PloS one 2014; 9:e93498
Beigel Florian, Friedrich Matthias, Probst Corina, Sotlar Karl, Göke Burkhard, Diegelmann Julia, Brand Stephan
Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2
Diegelmann J, Glas J, Franke A, Göke B, Bedynek A, Olszak T, Zimmermann E, Le Bras E, Czamara D, Brand S. Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2. PloS one 2013; 8:e77773.
Nov 5, 2013Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2
Nov 5, 2013PloS one 2013; 8:e77773
Diegelmann Julia, Glas Jürgen, Franke Andre, Göke Burkhard, Bedynek Andrea, Olszak Torsten, Zimmermann Eva, Le Bras Emmanuelle, Czamara Darina, Brand Stephan
Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment
Tillack C, Koburger M, Wagner J, Glas J, Diegelmann J, Koglin S, Dombrowski Y, Schauber J, Wollenberg A, Maier H, Wetzke M, Ehmann L, Friedrich M, Laubender R, Papay P, Vogelsang H, Stallhofer J, Beigel F, Bedynek A, Brand S. Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment. Gut 2013; 63:567-77.
Mar 6, 2013Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment
Mar 6, 2013Gut 2013; 63:567-77
Tillack Cornelia, Koburger Maria, Wagner Johanna, Glas Jürgen, Diegelmann Julia, Koglin Sarah, Dombrowski Yvonne, Schauber Jürgen, Wollenberg Andreas, Maier Harald, Wetzke Martin, Ehmann Laura Maximiliane, Friedrich Matthias, Laubender Rüdiger P, Papay Pavol, Vogelsang Harald, Stallhofer Johannes, Beigel Florian, Bedynek Andrea, Brand Stephan
IRGM variants and susceptibility to inflammatory bowel disease in the German population
Glas J, Czamara D, Diegelmann J, Göke B, Friedrich M, Steib C, Beigel F, Wetzke M, Tsekeri E, Olszak T, Fries C, Stallhofer J, Bues S, Seiderer J, Brand S. IRGM variants and susceptibility to inflammatory bowel disease in the German population. PloS one 2013; 8:e54338.
Jan 24, 2013IRGM variants and susceptibility to inflammatory bowel disease in the German population
Jan 24, 2013PloS one 2013; 8:e54338
Glas Jürgen, Czamara Darina, Diegelmann Julia, Göke Burkhard, Friedrich Matthias, Steib Christian, Beigel Florian, Wetzke Martin, Tsekeri Eleni, Olszak Torsten, Fries Christoph, Stallhofer Johannes, Bues Stephanie, Seiderer Julia, Brand Stephan
PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites
Glas J, Duerr R, Franke A, Kamboh M, Achkar J, Balschun T, Müller-Myhsok B, Wolf C, Olszak T, Wetzke M, Diegelmann J, Pasciuto G, Czamara D, Seiderer J, Brand S. PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites. PloS one 2012; 7:e52873.
Dec 27, 2012PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites
Dec 27, 2012PloS one 2012; 7:e52873
Glas Jürgen, Duerr Richard H, Franke Andre, Kamboh M Ilyas, Achkar Jean-Paul, Balschun Tobias, Müller-Myhsok Bertram, Wolf Christiane, Olszak Torsten, Wetzke Martin, Diegelmann Julia, Pasciuto Giulia, Czamara Darina, Seiderer Julia, Brand Stephan
Analysis of IL12B gene variants in inflammatory bowel disease
Glas J, Czamara D, Diegelmann J, Ochsenkühn T, Göke B, Wetzke M, Steib C, Stallhofer J, Beigel F, Friedrich M, Tillack C, Fries C, Olszak T, Wagner J, Seiderer J, Brand S. Analysis of IL12B gene variants in inflammatory bowel disease. PloS one 2012; 7:e34349.
Mar 30, 2012Analysis of IL12B gene variants in inflammatory bowel disease
Mar 30, 2012PloS one 2012; 7:e34349
Glas Jürgen, Czamara Darina, Diegelmann Julia, Ochsenkühn Thomas, Göke Burkhard, Wetzke Martin, Steib Christian, Stallhofer Johannes, Beigel Florian, Friedrich Matthias, Tillack Cornelia, Fries Christoph, Olszak Torsten, Wagner Johanna, Seiderer Julia, Brand Stephan
PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background
Glas J, Czamara D, Diegelmann J, Karbalai N, Ochsenkühn T, Göke B, Steib C, Friedrich M, Stallhofer J, Tillack C, Beigel F, Wetzke M, Olszak T, Seiderer J, Wagner J, Brand S. PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background. PloS one 2012; 7:e33682.
Mar 21, 2012PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background
Mar 21, 2012PloS one 2012; 7:e33682
Glas Jürgen, Czamara Darina, Diegelmann Julia, Karbalai Nazanin, Ochsenkühn Thomas, Göke Burkhard, Steib Christian, Friedrich Matthias, Stallhofer Johannes, Tillack Cornelia, Beigel Florian, Wetzke Martin, Olszak Torsten, Seiderer Julia, Wagner Johanna, Brand Stephan
The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease
Glas J, Czamara D, Diegelmann J, Friedrich M, Steib C, Beigel F, Olszak T, Tillack C, Fries C, Wetzke M, Bayrle C, Seiderer J, Brand S. The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease. PloS one 2011; 6:e29309.
Dec 29, 2011The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease
Dec 29, 2011PloS one 2011; 6:e29309
Glas Jürgen, Czamara Darina, Diegelmann Julia, Friedrich Matthias, Steib Christian, Beigel Florian, Olszak Torsten, Tillack Cornelia, Fries Christoph, Wetzke Martin, Bayrle Corinna, Seiderer Julia, Brand Stephan
A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-inflammatory proteins
Diegelmann J, Olszak T, Göke B, Blumberg R, Brand S. A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-inflammatory proteins. J Biol Chem 2011; 287:286-98.
Nov 8, 2011A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-inflammatory proteins
Nov 8, 2011J Biol Chem 2011; 287:286-98
Diegelmann Julia, Olszak Torsten, Göke Burkhard, Blumberg Richard S, Brand Stephan
CEACAM6 gene variants in inflammatory bowel disease
Glas J, Czamara D, Diegelmann J, Müller-Myhsok B, Lohse P, Wolf C, Ochsenkühn T, Göke B, Lass U, Olszak T, Beigel F, Weidinger M, Pfennig S, Tillack C, Fries C, Seiderer J, Brand S. CEACAM6 gene variants in inflammatory bowel disease. PloS one 2011; 6:e19319.
Apr 29, 2011CEACAM6 gene variants in inflammatory bowel disease
Apr 29, 2011PloS one 2011; 6:e19319
Glas Jürgen, Czamara Darina, Diegelmann Julia, Müller-Myhsok Bertram, Lohse Peter, Wolf Christiane, Ochsenkühn Thomas, Göke Burkhard, Lass Ulrich, Olszak Torsten, Beigel Florian, Weidinger Maria, Pfennig Simone, Tillack Cornelia, Fries Christoph, Seiderer Julia, Brand Stephan
The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants
Glas J, Czamara D, Diegelmann J, Lohse P, Ochsenkühn T, Göke B, Müller-Myhsok B, Weidinger M, Laubender R, Olszak T, Jürgens M, Beigel F, Pfennig S, Tillack C, Seiderer J, Brand S. The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants. PloS one 2010; 5:e14466.
Dec 30, 2010The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants
Dec 30, 2010PloS one 2010; 5:e14466
Glas Jürgen, Czamara Darina, Diegelmann Julia, Lohse Peter, Ochsenkühn Thomas, Göke Burkhard, Müller-Myhsok Bertram, Weidinger Maria, Laubender Rüdiger P, Olszak Torsten, Jürgens Matthias, Beigel Florian, Pfennig Simone, Tillack Cornelia, Seiderer Julia, Brand Stephan
Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus
Diegelmann J, Beigel F, Zitzmann K, Kaul A, Göke B, Auernhammer C, Bartenschlager R, Diepolder H, Brand S. Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus. PloS one 2010; 5:e15200.
Dec 8, 2010Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus
Dec 8, 2010PloS one 2010; 5:e15200
Diegelmann Julia, Beigel Florian, Zitzmann Kathrin, Kaul Artur, Göke Burkhard, Auernhammer Christoph J, Bartenschlager Ralf, Diepolder Helmut M, Brand Stephan
Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease
Glas J, Czamara D, Diegelmann J, Müller-Myhsok B, Folwaczny M, Ochsenkühn T, Göke B, Weidinger M, Olszak T, Beigel F, Wetzke M, Pfennig S, Tengler B, Fischer D, Seiderer J, Brand S. Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease. Inflamm Bowel Dis 2010; 17:1917-24.
Dec 3, 2010Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease
Dec 3, 2010Inflamm Bowel Dis 2010; 17:1917-24
Glas Jürgen, Czamara Darina, Diegelmann Julia, Müller-Myhsok Bertram, Folwaczny Matthias, Ochsenkühn Thomas, Göke Burkhard, Weidinger Maria, Olszak Torsten, Beigel Florian, Wetzke Martin, Pfennig Simone, Tengler Barbara, Fischer Daniel, Seiderer Julia, Brand Stephan
Functional SFTPD gene variants are not associated with susceptibility to inflammatory bowel disease in the German population
Glas J, Seiderer J, Tillack C, Paschos E, Wetzke M, Diegelmann J, Czamara D, Brand S. Functional SFTPD gene variants are not associated with susceptibility to inflammatory bowel disease in the German population. Inflamm Bowel Dis 2010; 17:1439-40.
Dec 3, 2010Functional SFTPD gene variants are not associated with susceptibility to inflammatory bowel disease in the German population
Dec 3, 2010Inflamm Bowel Dis 2010; 17:1439-40
Glas Jürgen, Seiderer Julia, Tillack Cornelia, Paschos Ekaterini, Wetzke Martin, Diegelmann Julia, Czamara Darina, Brand Stephan