PD Dr. med. Christian Kahlert
attending physician mbF
Division of Infectious Diseases, Infection Prevention and Travel Medicine · Dept. I
Assessment of Torque Teno Virus (TTV) viral load as marker for baseline immunity in healthcare workers
Dec 2, 2024This project will retrospectively assess the association of SARS-CoV-2 vaccination status with TTV viral loads in a cohort of healthcare workers and correlation with susceptibility to respiratory infections, determined by total number of influenza-li...
Clinical Studies - Dec 2, 2024 - Oct 31, 2025
Scheduled
Project leader: Kohler Philipp
Members: Kuster Stefan, Kahlert Christian, Grässli Fabian
Humoral immunity and risk factors for Alongshan-virus in healthcare workers from Eastern Switzerland –proposal for a seroepidemiologic analysis
Aug 1, 2024In dieser prospektiven Studie innerhalb der SURPRISE+ Kohorte möchten wir die Seroprävalenz und Serokonversion gegen das Alongshan-Virus (ALSV). ALSV ist ein Flavivirus, welches ein FSME-ähnliches Krankheitsbild auslösen kann. Das Virus wird häufig i...
Clinical Studies - Aug 1, 2024 - Feb 28, 2026
Ongoing
Project leader: Kohler Philipp
Members: Frischknecht Manuel, Kuster Stefan, Kahlert Christian
Impact of Tenofovir disoproxil fumarate/Emtricitabine (TDF/FTC) on the gut microbiome and microbiome-mediated toxicity of TDF/FTC in men using event-based HIV Pre- Exposure prophylaxis
Jun 1, 2023
Clinical Studies - Jun 1, 2023 - Mar 31, 2025
Ongoing
Project leader: Notter Julia
Members: Kahlert Christian
Exploring the impact of hexagonal boron nitride (nanomedicines) on bacterial quorum sensing communication and its consequences on bacterial lung invasionand pathogenesis
Jan 3, 2023In this interdisciplinary collaboration between Empa's Laboratory for Particles-Biology Interactions (Particles@Barriers subgroup) and the KSSG (Infektiologie/Spitalhygiene), we aim to study whether hexagonal boron nitride (hBN) could modulate host-i...
Fundamental Research - Jan 3, 2023 - Jan 2, 2024
Automatically Closed
Project leader: Albrich Werner, Bürki-Turnherr Tina, Kahlert Christian
Members: Nigg Susanne
Fluorescence-based rapid diagnostic tool for sensitive and selective Detection Of uReaSeproducing bacTEria causing ventilator-associated Pneumonia - DOORSTEP
May 2, 2022
Fundamental Research - May 2, 2022 - May 1, 2023
Automatically Closed
Project leader: Giovannini G
Members: Kahlert Christian, Nigg Susanne
Covid 19 Impfantwort, Bedarf und Reaktion auf mögliche Booster- Impfung bei Patienten mit soliden Neoplasien
Oct 1, 2021Patienten mit malignen Erkrankungen stellen eine durch die SARS-CoV-2-Pandemie hoch gefährdete Gruppe dar mit einem hohen Hospitalisations- und Mortalitätsrisiko. Eine Impfung gegen SARS-COV2 stellt neben allgemeinen Schutzmassnahmen das wichtigste E...
Clinical Studies - Oct 1, 2021 - Feb 28, 2021
Automatically Closed
Project leader: Fischer Stefanie
Members: Silzle Tobias, Demmer-Steingruber Ruth, Albrich Werner, Kahlert Christian
Response to COVID-19 vaccination and COVID-19 infections after vaccination in patients with haematological malignancies
May 1, 2021The prevalence and mortality of COVID-19 are higher in patients with haematological malignancies (HM) compared to the general population (Vijenthira et al. 2020). Two SARS-CoV-2 messenger RNA (mRNA) vaccines have been approved by Swissmedic, both are...
Clinical Studies - May 1, 2021 - Oct 1, 2022
Completed
Project leader: Silzle Tobias
Members: Fischer Stefanie, Kahlert Christian, Albrich Werner
CRiPSI/CRiPSI-X: Covid-19 Risk Prediction in Swiss ICUs-Trial/Extension
Aug 1, 2020Outcome of patients with critical Covid-19 varies. We study risk of and predictors for poor outcome in adult patients with Covid-19 admitted to ICU in a multicenter study. In addition, we assess the prevalence of, risk factors for and mechanisms invo...
Clinical Studies - Aug 1, 2020 - Aug 31, 2022
Automatically Closed
Project leader: Albrich Werner
Members: Von Mering Christian, O'Mahony Liam, Cerny Andreas, Suh Noémie, El Baz Yassir, Dietrich Tobias, Fischer Tim, Felbecker Ansgar, Göhl-Freyn Kristina, Germann Nicolas, Schmid Dagmar, Kahlert Christian, Frischknecht Manuel, Filipovic Miodrag, Brutsche Martin, Pietsch Urs, Kleger Gian-Reto, Bochud Pierre-Yves
Metabolism of antiretroviral drugs in HIV infected patients with toxicity – a pilot study
Jan 1, 2020Antiretroviral drugs can be responsible for a wide range of toxic side effects ranging from acute events to long-term toxicity. We hypothesize that the microbiome-mediated metabolism plays a substantial role in antiretroviral drug toxicity through se...
Clinical Studies - Jan 1, 2020 - Dec 31, 2020
Automatically Closed
Project leader: Notter Julia, Zimmermann Michael, Kahlert Christian
Clinical impact of multiplex realtime PCR in respiratory tract infections
Nov 15, 2014Pathogen detection in respiratory tract infections is challenging due to lack of diagnostic gold standard with sufficient sensitivity and specificity. Viral infections likely contribute to a considerable portion of respiratory tract infections partic...
Clinical Studies - Nov 15, 2014 - Dec 31, 2015
Automatically Closed
Project leader: Albrich Werner
Members: Kahlert Christian, Rassouli Frank, Mayer Lena
Airway microbiota resistome in CF - impact on clinical management
Sep 1, 2014Cystic Fibrosis is a deadly genetic disease mainly due to chronic bacterial colonization and recurrent bacterial infections of the lungs. It has often been documented that once a certain microbial species such as Pseudomonas aeruginosa establishes, t...
Fundamental Research - Sep 1, 2014 - Dec 31, 2016
Automatically Closed
Project leader: Baty Florent
Members: Brutsche Martin, Kahlert Christian, Von Mering Christian, Vyas Rounak
Human airway epithelia and pneumococcus. Polarized in vitro cell culture model to study interaction between human airway epithelia and pneumococcus
Jan 1, 2014This project aims to extend the existing human airway epithelial model to enable studies on the most relevant and lethal respiratory bacterial pathogen, Streptococcus pneumoniae (SP). The primary goal of this proposal is to show the feasibility of th...
Fundamental Research - Jan 1, 2014 - Dec 31, 2014
Automatically Closed
Project leader: Albrich Werner, Kahlert Christian
Unravelling the Evil - the role of CXCL-10 antagonist in HIV+ failing immune recovery despite cART
Jul 1, 2013Although highly active antiretroviral therapy (HAART) leads in general to CD4+ T-cell recovery and decrease of general immune activation, therefore improving individuals’ long-term prognosis, in a clinically significant percentage of 20% of HIV-infec...
Fundamental Research - Jul 1, 2013 - Apr 30, 2014
Automatically Closed
Project leader: Hoffmann Matthias
Members: Schmid Patrick, Kahlert Christian, Vernazza Pietro
Modulation of inflammation by Lactobacillus rhamnosus GG in pediatric patients with cystic fibrosis
Dec 1, 2012Die zystische Fibrose ist eine komplexe, genetisch determinierte aber bisher unheilbare Multiorganerkrankung mit phänotypischem Hauptmerkmal einer ätiologisch nicht sicher geklärten chronischen Entzündung im Respirationstrakt. Dies führt zu rezidivie...
Clinical Studies - Dec 1, 2012 - Dec 31, 2015
Automatically Closed
Project leader: Kahlert Christian, Müller Pascal
HIV in der Adoleszenz - Transition in die Erwachsenenbetreuung (HIVTAC)
Jan 12, 2012ORIGINALTITEL HIV infected adolescents in transition to adult care (the HIV-TAC project). Health status and continuity of care, needs and perceptions HINTERGRUND Seit Einführung der kombinierten antiretroviralen Therapie (cART) steigt weltweit die Z...
Clinical Studies - Jan 12, 2012 - Dec 31, 2015
Automatically Closed
Project leader: Kahlert Christian, Nicca Dunja