Ronald Dijkman
Secretome analysis of the human airway epithelium following human respiratory virus infection
Jan 1, 2013The human airway epithelium represents the entry port of many human respiratory viruses, such as respiratory syncytial virus (RSV), influenza A viruses (IAV), and human coronaviruses (HCoV). It represents the interface between the external world and...
Fundamental Research - Jan 1, 2013 - Dec 31, 2013
Completed
Project leader: Thiel Volker
Members: Dijkman Ronald, Jonsdottir Hulda
Genetic modification of the human airway epthelium - a paradigmatic system to study host responses to human respiratory viruses
Jul 1, 2012Das menschliche Atemwegsepithelium ist die Haupteintrittspforte für viele respiratorische Viren. Obwohl primäre humane Epithelzellen in Form eines Atemwegsepitheliums, das in vieler Hinsicht den in vivo Verhältnissen entspricht, kultiviert werden kön...
Fundamental Research - Jul 1, 2012 - Dec 31, 2013
Completed
Project leader: Thiel Volker
Members: Jonsdottir Hulda, Dijkman Ronald
Genetic modification of the human airway epithelium – a paradigmatic system to study host responses to human respiratory viruses
Jan 1, 2012The goal of this project is to establish a unique experimental system to study fundamental aspects of human respiratory virus replication and interactions with the innate immune system at the natural entry port of human respiratory viruses, namely th...
Fundamental Research - Jan 1, 2012 - Dec 31, 2012
Completed
Project leader: Thiel Volker
Members: Dijkman Ronald
Impact of RNA modification on coronavirus-induced innate immune responses
Oct 1, 2010Eukaryotic messenger RNAs (mRNAs) play a universal role as transcripts of the genomic information that is used for the translation into proteins of a cell. Similarly, viruses that infect eukaryotic host cells produce viral mRNAs from their genome in...
Fundamental Research - Oct 1, 2010 - Sep 30, 2013
Completed
Project leader: Thiel Volker
Members: Kindler Eveline, Dijkman Ronald