PD Dr. med Jan Borovicka
chief of service
Gastroenterology/Hepatology · Dept. I
Point Prevalence of Antibiotic Resistance in Helicobacter pylori in St. Gallen: An Observational Pilot Trial
May 1, 2024Evaluation der Antibiotika-Resistenz von Helicobacter pylori Magen und Überprüfung der Konsistenz von Resistenzdaten aus dem Stuhl und aus Magenbiopsien
Clinical Studies - May 1, 2024 - Jun 30, 2025
Scheduled
Project leader: Kueres-Wiese Alexander
Members: Kuster Stefan, Frei Nicola Fabian, Borovicka Jan
Anal Mapping Biopsies for Human Papilloma Virus (HPV) Associated Lesions
Oct 4, 2017Es gibt keinen eindeutigen Goldstandard für die Diagnose von HPV-assoziierten Analläsionen. Die übliche Diagnostik erfolgt mittels hochauflösender Anoskopie (HRA). Die diagnostische Genauigkeit dieser Methode ist jedoch unklar und stark vom Prüfer ab...
Clinical Studies - Oct 4, 2017 - Feb 4, 2018
Completed
Project leader: Baumeler Stephan, Borovicka Jan, Marti Lukas
Members: Maurus Christine
First Experiences with Screening of Anal Intraepithelial Neoplasia (AIN): a Single Center Retrospective Data-Analysis
Sep 1, 2017Hintergrund Zwischen Human Papilloma Virus (HPV) und Analkrebs besteht eine starke Korrelation. Wie beim Cervixkarzinom der Frau sind mehr als 80% der Analkarzinome durch HPV bedingt. Analkrebs geht meist aus Vorläuferläsionen, den analen intraepithe...
Clinical Studies - Sep 1, 2017 - Sep 2, 2018
Automatically Closed
Project leader: Baumeler Stephan
Members: Maurus Christine, Marti Lukas, Borovicka Jan, Bock Susanne, Bischofberger Stephan, Schmid Patrick
GA29145
Aug 28, 2017AN OPEN-LABEL EXTENSION AND SAFETY MONITORING STUDY OF PATIENTS WITH MODERATELY TO SEVERELY ACTIVE CROHN’S DISEASE PREVIOUSLY ENROLLED IN THE ETROLIZUMAB PHASE III PROTOCOL GA29144
Clinical Studies - Aug 28, 2017 - Aug 28, 2021
Automatically Closed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
GA29144/Bergamot
Aug 1, 2017A PHASE III, RANDOMIZED, DOUBLEBLIND, PLACEBOCONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ETROLIZUMAB AS AN INDUCTION AND MAINTENANCE TREATMENT FOR PATIENTS WITH MODERATELY TO SEVERELY ACTIVE CROHN’S DISEASE
Clinical Studies - Aug 1, 2017 - Aug 1, 2021
Automatically Closed
Project leader: Borovicka Jan, Brand Stephan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
Evaluation of High Resolution Endoscopy Compared to the High Resolution Anoscopy for Detection of Early Dysplastic or Neoplastic Lesions of the Anal Canal in High−Risk Patients
Apr 17, 2017There is a strong correlation between HPV infection and anal squamous cell cancer (SCC). Just like in nearly 100% of cervical cancer, infection with human papillomavirus (HPV) high-risk types causes more than 80% of anal cancer. Nevertheless the natu...
Clinical Studies - Apr 17, 2017 - Apr 17, 2019
Automatically Closed
Project leader: Baumeler Stephan
Members: Borovicka Jan, Maurus Christine
GA289103/Gardenia
Jun 28, 2015GA29103: PHASE III, RANDOMIZED, MULTICENTER DOUBLE-BLIND, DOUBLE-DUMMY STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ETROLIZUMAB COMPARED WITH INFLIXIMAB IN PATIENTS WITH MODERATE TO SEVERE ACTIVE ULCERATIVE COLITIS WHO ARE NAIVE TO TNF INHIBITORS
Clinical Studies - Jun 28, 2015 - Jun 28, 2020
Automatically Closed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Sulz Michael, Semadeni Gian-Marco
Abbvie M 14-347
Mar 1, 2015A Multicenter, Open-Label Study to Evaluate the Long Term Efficacy, Safety, and Tolerability of Repeated Administration of Adalimumab in Subjects with Crohn's Disease
Clinical Studies - Mar 1, 2015 - Dec 1, 2017
Completed
Project leader: Borovicka Jan
Members: Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
Abbvie M14-033
Mar 1, 2015A Double-Blind, Randomized, Multicenter Study of Higher Versus Standard Adalimumab Dosing Regimens for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis This Phase 3 study design includes a Screening...
Clinical Studies - Mar 1, 2015 - Feb 1, 2018
Automatically Closed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
ALERT
Feb 28, 2015VAlidation of an 8-‐item-‐questionnaire predictive for a positive CaLprotectin tEst and Real-‐life implemenTation in primary care to reduce diagnostic delay in inflammatory bowel disease
Clinical Studies - Feb 28, 2015 - Jan 30, 2017
Completed
Project leader: Borovicka Jan
Members: Dora Barbara, Sulz Michael
GA28950/Hickory
Jan 1, 2015PHASE III, BLINDED, PLACEBO-CONTROLLED, MULTICENTER STUDY OF THE EFFICACY AND SAFETY OF ETROLIZUMAB DURING INDUCTION AND MAINTENANCE IN PATIENTS WITH MODERATE TO SEVERE ACTIVE ULCERATIVE COLITIS WHO ARE REFRACTORY TO OR INTOLERANT OF TNF INHIBITORS
Clinical Studies - Jan 1, 2015 - Dec 31, 2017
Automatically Closed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
GA28951
Jun 28, 2014GA28951: AN OPEN-LABEL EXTENSION AND SAFETY MONITORING STUDY OF MODERATE TO SEVERE ULCERATIVE COLITIS PATIENTS PREVIOUSLY ENROLLED IN ETROLIZUMAB PHASE III STUDIES
Clinical Studies - Jun 28, 2014 - Jun 28, 2020
Completed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
Bern Cohort study of patients with hepatocellular carcinoma
Apr 16, 2014This is a cohort study in consecutive patients with diagnosed HCC referred to a tertiary care hospital with follow-ups every 3 months until death or transplantation.
Clinical Studies - Apr 16, 2014 - Apr 16, 2023
Automatically Closed
Project leader: Semela David
Members: Weinmann Sabine, Künzler-Heule Patrizia, Borovicka Jan, Frei Remus, Sawatzki Mikael, Semadeni Gian-Marco, Sulz Michael
Treatment of non-alcoholic steatohepatitis (NASH) patients with vitamin D
Nov 21, 2012Die Fettlebererkrankung ist eine global stark zunehmende Erkrankung, die insbesondere bei begleitender Entzündung der Leber (Fettleberhepatitis; NASH) zumeist zu einem fortschreitenden Leberschaden führt. Das Endstadium dieser Erkrankung bilden die L...
Clinical Studies - Nov 21, 2012 - Mar 31, 2015
Automatically Closed
Project leader: Semela David
Members: Sawatzki Mikael, Sulz Michael, Borovicka Jan, Weinmann Sabine, Künzler-Heule Patrizia
Diagnostic value of calprotectin measurement in ascitic fluid for the diagnosis of Spontaneous Bac-terial Peritonitis
Oct 9, 2012Die Korrelation der Calprotectin-Messung mittels laborbasiertem Test und dem Schnelltest mit der Auszäh-lung der weißen Blutkörperchen im Mikroskop. Die Wertigkeit der Calprotectin-Messung zur Diagnose einer bakteriellen Bauchfellentzündung bei Pati...
Clinical Studies - Oct 9, 2012 - Apr 16, 2014
Completed
Project leader: Semela David
Members: Borovicka Jan, Frei Remus, Sawatzki Mikael, Semadeni Gian-Marco, Sulz Michael, Künzler-Heule Patrizia, Weinmann Sabine
INSPIRADA
Jun 14, 2012An Open-Label Multicenter Study to Evaluate the Impact of Adalimumab on Quality of Life, Health Care Utilization and Costs of Ulcerative Colitis Subjects in the Usual Clinical Practice Setting The primary objective is to assess the effect of adalimu...
Clinical Studies - Jun 14, 2012 - Jun 30, 2014
Completed
Project leader: Borovicka Jan
Members: Frei Remus, Knellwolf Christina
Non-Interventional Cohort Study on the Utilization and Impact of Dual and Triple Therapies Based on Pegylated Interferon for the Treatment of Chronic Hepatitis C
Apr 2, 2012Beurteilung der Wirksamkeit von Kombinationstherapien mit Peginterferon alpha plus Ribavirin und Therapieschemata mit direkt wirkenden antiviralen Substanzen bei CHC-Patienten, die diese Medikamente im Rahmen der klinischen Routinepraxis gemäss den l...
Clinical Studies - Apr 2, 2012 - Nov 30, 2014
Completed
Project leader: Semela David
Members: Borovicka Jan, Frei Remus, Sulz Michael, Sawatzki Mikael, Semadeni Gian-Marco, Künzler-Heule Patrizia, Weinmann Sabine
An International, Multi-Center Study Evaluating the Correlation of IL28B Genotypes with Chronic Hepatitis C Disease Characteristics and Patient Demographics
Apr 2, 2012Korrelation zwischen den Interleukin 28B - (IL28B-) Genotypen rs12979860 (CC vs. TC vs. TT) und rs8099917 (TT vs. GT vs. GG) und CHC-assoziierter Leberfibrose
Clinical Studies - Apr 2, 2012 - May 30, 2014
Completed
Project leader: Semela David
Members: Borovicka Jan, Frei Remus, Sawatzki Mikael, Semadeni Gian-Marco, Sulz Michael, Künzler-Heule Patrizia, Weinmann Sabine
Eine randomisierte, doppelblinde klinische Prüfung der Phase III zur Untersuchung der Wirksamkeit, Si-cherheit und Verträglichkeit von TMC435 vs. Telaprevir, beide in Kombination mit PegIFNα-2a und Ribavirin, bei Patienten mit chronischer Hepatitis-C-Genotyp-1-Infektion, die bei einer früheren Therapie mit PegIFNα- und Ribavirin Null- oder partielle Responder waren
Feb 6, 2012To demonstrate the non-inferiority of TMC435 versus telaprevir (TVR), both given in combination with peginterferon-alfa-2a (PegIFNα-2a) and ribavirin (RBV), by less than 12% with respect to the proportion of subjects with sustained virologic response...
Clinical Studies - Feb 6, 2012 - May 31, 2014
Completed
Project leader: Semela David
Members: Borovicka Jan, Sulz Michael, Sawatzki Mikael, Semadeni Gian-Marco, Künzler-Heule Patrizia, Weinmann Sabine
Multicenter, Open-Label, Early Access Program of Telaprevir in Combination With Peginterferon Alfa and Ribavirin in Genotype 1 Chronic Hepatitis C Subjects With Severe Fibrosis and Compensated Cirrhosis
May 30, 2011A multicenter, multinational, open-label, non-comparative early access program designed to provide telaprevir to subjects who are expected to benefit from telaprevir-based therapy and to collect additional safety and tolerability data on telaprevir t...
Clinical Studies - May 30, 2011 - May 30, 2013
Completed
Project leader: Semela David
Members: Borovicka Jan, Sawatzki Mikael, Künzler-Heule Patrizia