Prof. Dr. med. Wolfram Jochum
chief physician
Pathologie · Dept. IV
Multi-laboratory proficiency testing of clinical cancer genomic profiling by next-generation sequencing
Zhong Q, Diebold J, McKee T, Jochum W, Kashofer K, Hofman P, Zischka M, Moch H, Rechsteiner M, Rogel U, Vassella E, Wagner U, Kurt H, Molinari F, Cathomas G, Komminoth P, Barman-Aksözen J, Schneider-Yin X, Rey J, Wild P. Multi-laboratory proficiency testing of clinical cancer genomic profiling by next-generation sequencing. Pathol Res Pract 2018; 214:957-963.
May 22, 2018Multi-laboratory proficiency testing of clinical cancer genomic profiling by next-generation sequencing
May 22, 2018Pathol Res Pract 2018; 214:957-963
Zhong Qing, Diebold Joachim, McKee Thomas, Jochum Wolfram, Kashofer Karl, Hofman Paul, Zischka Melanie, Moch Holger, Rechsteiner Markus, Rogel Uwe, Vassella Erik, Wagner Ulrich, Kurt Henriette, Molinari Francesca, Cathomas Gieri, Komminoth Paul, Barman-Aksözen Jasmin, Schneider-Yin Xiaoye, Rey Jean-Philippe, Wild Peter J
Anti-PD-1 Therapy Leads to Near-Complete Remission in a Patient with Metastatic Basal Cell Carcinoma
Fischer S, Ali O, Jochum W, Kluckert J, Flatz L, Siano M. Anti-PD-1 Therapy Leads to Near-Complete Remission in a Patient with Metastatic Basal Cell Carcinoma. Oncol Res Treat 2018; 41:391-394.
May 3, 2018Anti-PD-1 Therapy Leads to Near-Complete Remission in a Patient with Metastatic Basal Cell Carcinoma
May 3, 2018Oncol Res Treat 2018; 41:391-394
Fischer Stefanie, Ali Omar H, Jochum Wolfram, Kluckert Jörg-Thomas, Flatz Lukas, Siano Marco
Reappraisal of Morphologic Differences Between Renal Medullary Carcinoma, Collecting Duct Carcinoma, and Fumarate Hydratase-deficient Renal Cell Carcinoma
Ohe C, Kunju L, Maclean F, Magi-Galluzzi C, McKenney J, Mehra R, Nesi G, Osunkoya A, Picken M, Rao P, Reuter V, de Oliveira Salles P, Schultz L, Tickoo S, Tomlins S, Trpkov K, Jochum W, Hirsch M, Hes O, Smith S, Sirohi D, Divatia M, de Peralta-Venturina M, Paner G, Agaimy A, Amin M, Argani P, Chen Y, Cheng L, Colecchia M, Compérat E, Werneck da Cunha I, Epstein J, Gill A, Amin M. Reappraisal of Morphologic Differences Between Renal Medullary Carcinoma, Collecting Duct Carcinoma, and Fumarate Hydratase-deficient Renal Cell Carcinoma. Am J Surg Pathol 2018; 42:279-292.
Mar 1, 2018Reappraisal of Morphologic Differences Between Renal Medullary Carcinoma, Collecting Duct Carcinoma, and Fumarate Hydratase-deficient Renal Cell Carcinoma
Mar 1, 2018Am J Surg Pathol 2018; 42:279-292
Ohe Chisato, Kunju Lakshmi P, Maclean Fiona, Magi-Galluzzi Cristina, McKenney Jesse K, Mehra Rohit, Nesi Gabriella, Osunkoya Adeboye O, Picken Maria M, Rao Priya, Reuter Victor E, de Oliveira Salles Paulo Guilherme, Schultz Luciana, Tickoo Satish K, Tomlins Scott A, Trpkov Kiril, Jochum Wolfram, Hirsch Michelle S, Hes Ondrej, Smith Steven C, Sirohi Deepika, Divatia Mukul, de Peralta-Venturina Mariza, Paner Gladell P, Agaimy Abbas, Amin Mitual B, Argani Pedram, Chen Ying-Bei, Cheng Liang, Colecchia Maurizio, Compérat Eva, Werneck da Cunha Isabela, Epstein Jonathan I, Gill Anthony J, Amin Mahul B
CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
Cheng H, Brutsche M, Jochum W, Schneider T, Rodriguez R, Tarantino I, Pikor N, Novkovic M, Bösch M, Cupovic J, Onder L, Ludewig B. CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses. J Allergy Clin Immunol 2018
Jan 31, 2018CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
Jan 31, 2018J Allergy Clin Immunol 2018
Cheng Hung-Wei, Brutsche Martin, Jochum Wolfram, Schneider Tino, Rodriguez Regulo, Tarantino Ignazio, Pikor Natalia, Novkovic Mario, Bösch Maximilian, Cupovic Jovana, Onder Lucas, Ludewig Burkhard
Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness
Bösch M, Knauer M, Ruhstaller T, Jochum W, Gastl G, Sopper S, Mörbe U, Novkovic M, Cheng H, Onder L, Ludewig B. Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness. Oncoimmunology 2018; 7:e1414129.
Jan 3, 2018Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness
Jan 3, 2018Oncoimmunology 2018; 7:e1414129
Bösch Maximilian, Knauer Michael, Ruhstaller Thomas, Jochum Wolfram, Gastl Guenther, Sopper Sieghart, Mörbe Urs, Novkovic Mario, Cheng Hung-Wei, Onder Lucas, Ludewig Burkhard
Prognostic value of MIB-1 proliferation index in solitary fibrous tumors of the pleura implemented in a new score - a multicenter study
Diebold M, Kohler M, Oezkan F, Darwiche K, Berezowska S, Theegarten D, Grobholz R, Jochum W, Komminoth P, Bubendorf L, Haile S, Hottinger S, Soltermann A, Franzen D. Prognostic value of MIB-1 proliferation index in solitary fibrous tumors of the pleura implemented in a new score - a multicenter study. Respir Res 2017; 18:210.
Dec 16, 2017Prognostic value of MIB-1 proliferation index in solitary fibrous tumors of the pleura implemented in a new score - a multicenter study
Dec 16, 2017Respir Res 2017; 18:210
Diebold Matthias, Kohler Malcolm, Oezkan Filiz, Darwiche Kaid, Berezowska Sabina, Theegarten Dirk, Grobholz Rainer, Jochum Wolfram, Komminoth Paul, Bubendorf Lukas, Haile Sarah R, Hottinger Selma, Soltermann Alex, Franzen Daniel P
Tumor infiltrating lymphocytes in lymph node metastases of stage III melanoma correspond to response and survival in nine patients treated with ipilimumab at the time of stage IV disease
Diem S, Hasan Ali O, Ackermann C, Bomze D, Koelzer V, Jochum W, Speiser D, Mertz K, Flatz L. Tumor infiltrating lymphocytes in lymph node metastases of stage III melanoma correspond to response and survival in nine patients treated with ipilimumab at the time of stage IV disease. Cancer Immunol Immunother 2017; 67:39-45.
Sep 11, 2017Tumor infiltrating lymphocytes in lymph node metastases of stage III melanoma correspond to response and survival in nine patients treated with ipilimumab at the time of stage IV disease
Sep 11, 2017Cancer Immunol Immunother 2017; 67:39-45
Diem Stefan, Hasan Ali Omar, Ackermann Christoph J, Bomze David, Koelzer Viktor H, Jochum Wolfram, Speiser Daniel E, Mertz Kirsten D, Flatz Lukas
Neutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lymphocyte ratio (PLR) as prognostic markers in patients with non-small cell lung cancer (NSCLC) treated with nivolumab
Diem S, Schmid S, Krapf M, Flatz L, Born D, Jochum W, Templeton A, Früh M. Neutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lymphocyte ratio (PLR) as prognostic markers in patients with non-small cell lung cancer (NSCLC) treated with nivolumab. Lung Cancer 2017; 111:176-181.
Jul 24, 2017Neutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lymphocyte ratio (PLR) as prognostic markers in patients with non-small cell lung cancer (NSCLC) treated with nivolumab
Jul 24, 2017Lung Cancer 2017; 111:176-181
Diem Stefan, Schmid Sabine, Krapf Mirjam, Flatz Lukas, Born Diana, Jochum Wolfram, Templeton Arnoud J, Früh Martin
Impact of human papillomavirus on outcome in patients with oropharyngeal cancer treated with primary surgery
Broglie Däppen M, Müller M, Spreitzer S, Lang F, Lutchmaya M, Stauffer E, Espeli V, Martucci F, Bongiovanni M, Foerbs D, Arnoux A, Dettmer M, Arnold A, Stöckli S, Sauter R, Pasche P, Reinhard A, de Leval L, Huber G, Pezier T, Soltermann A, Giger R, Jochum W. Impact of human papillomavirus on outcome in patients with oropharyngeal cancer treated with primary surgery. Head & neck 2017; 39:2004-2015.
Jul 10, 2017Impact of human papillomavirus on outcome in patients with oropharyngeal cancer treated with primary surgery
Jul 10, 2017Head & neck 2017; 39:2004-2015
Broglie Däppen Martina, Müller Martin, Spreitzer Stefan, Lang Florian, Lutchmaya Mathieu, Stauffer Edouard, Espeli Vittoria, Martucci Francesco, Bongiovanni Massimo, Foerbs Diana, Arnoux Andre, Dettmer Matthias, Arnold Andreas, Stöckli Sandro, Sauter Rafael, Pasche Philippe, Reinhard Antoine, de Leval Laurence, Huber Gerhard F, Pezier Thomas F, Soltermann Alex, Giger Roland, Jochum Wolfram
Recurrent Dystrophic Calcification of the Prostatic Resection Cavity After Transurethral Resection of the Prostate: Clinical Presentation and Endoscopic Management
Zumstein V, Betschart P, Muellhaupt G, Jochum W, Schmid H, Abt D. Recurrent Dystrophic Calcification of the Prostatic Resection Cavity After Transurethral Resection of the Prostate: Clinical Presentation and Endoscopic Management. J Endourol Case Rep 2017; 3:81-83.
Jun 1, 2017Recurrent Dystrophic Calcification of the Prostatic Resection Cavity After Transurethral Resection of the Prostate: Clinical Presentation and Endoscopic Management
Jun 1, 2017J Endourol Case Rep 2017; 3:81-83
Zumstein Valentin, Betschart Patrick, Muellhaupt Gautier, Jochum Wolfram, Schmid Hans-Peter, Abt Dominik
Epidermal growth factor receptor and anaplastic lymphoma kinase testing and mutation prevalence in patients with advanced non-small cell lung cancer in Switzerland: A comprehensive evaluation of real world practices
Ess S, Herrmann C, Frick H, Krapf M, Cerny T, Jochum W, Früh M. Epidermal growth factor receptor and anaplastic lymphoma kinase testing and mutation prevalence in patients with advanced non-small cell lung cancer in Switzerland: A comprehensive evaluation of real world practices. Eur J Cancer Care (Engl) 2017
May 30, 2017Epidermal growth factor receptor and anaplastic lymphoma kinase testing and mutation prevalence in patients with advanced non-small cell lung cancer in Switzerland: A comprehensive evaluation of real world practices
May 30, 2017Eur J Cancer Care (Engl) 2017
Ess S M, Herrmann C, Frick H, Krapf M, Cerny T, Jochum Wolfram, Früh Martin
Evaluation of type-specific antibodies to high risk-human papillomavirus (HPV) proteins in patients with oropharyngeal cancer
Broglie Däppen M, Jochum W, Michel A, Waterboer T, Foerbs D, Schoenegg R, Stöckli S, Pawlita M, Holzinger D. Evaluation of type-specific antibodies to high risk-human papillomavirus (HPV) proteins in patients with oropharyngeal cancer. Oral Oncol 2017; 70:43-50.
May 25, 2017Evaluation of type-specific antibodies to high risk-human papillomavirus (HPV) proteins in patients with oropharyngeal cancer
May 25, 2017Oral Oncol 2017; 70:43-50
Broglie Däppen Martina, Jochum Wolfram, Michel Angelika, Waterboer Tim, Foerbs Diana, Schoenegg René, Stöckli Sandro, Pawlita Michael, Holzinger Dana
Impact of particle size and surface modification on gold nanoparticle penetration into human placental microtissues
Muoth C, Wick P, Jochum W, Wichser A, Grieder K, Diener L, Moya S, Astruc D, Ruiz J, Karst U, Großgarten M, Buerki-Thurnherr T. Impact of particle size and surface modification on gold nanoparticle penetration into human placental microtissues. Nanomedicine (Lond) 2017; 12:1119-1133.
Apr 27, 2017Impact of particle size and surface modification on gold nanoparticle penetration into human placental microtissues
Apr 27, 2017Nanomedicine (Lond) 2017; 12:1119-1133
Muoth Carina, Wick Peter, Jochum Wolfram, Wichser Adrian, Grieder Kathrin, Diener Liliane, Moya Sergio, Astruc Didier, Ruiz Jaime, Karst Uwe, Großgarten Mandy, Buerki-Thurnherr Tina
Vascular endothelial growth factor A amplification in colorectal cancer is associated with reduced M1 and M2 macrophages and diminished PD-1-expressing lymphocytes
Burmeister K, Tornillo L, Piscuoglio S, Ng C, Köberle D, Lehmann F, Moosmann P, Horber D, Jochum W, Grobholz R, Perrina V, Matter M, Eppenberger-Castori S, Andreozzi M, Quagliata L, Terracciano L. Vascular endothelial growth factor A amplification in colorectal cancer is associated with reduced M1 and M2 macrophages and diminished PD-1-expressing lymphocytes. PloS one 2017; 12:e0175563.
Apr 12, 2017Vascular endothelial growth factor A amplification in colorectal cancer is associated with reduced M1 and M2 macrophages and diminished PD-1-expressing lymphocytes
Apr 12, 2017PloS one 2017; 12:e0175563
Burmeister Katharina, Tornillo Luigi, Piscuoglio Salvatore, Ng Charlotte K Y, Köberle Dieter, Lehmann Frank, Moosmann Peter, Horber Daniel, Jochum Wolfram, Grobholz Rainer, Perrina Valeria, Matter Matthias S, Eppenberger-Castori Serenella, Andreozzi Mariacarla, Quagliata Luca, Terracciano Luigi M
Low tissue levels of miR-125b predict malignancy in solitary fibrous tumors of the pleura
Brock M, Hottinger S, Diebold M, Soltermann A, Jochum W, Kohler M, Huber L, Franzen D. Low tissue levels of miR-125b predict malignancy in solitary fibrous tumors of the pleura. Respir Res 2017; 18:43.
Mar 2, 2017Low tissue levels of miR-125b predict malignancy in solitary fibrous tumors of the pleura
Mar 2, 2017Respir Res 2017; 18:43
Brock Matthias, Hottinger Selma, Diebold Matthias, Soltermann Alex, Jochum Wolfram, Kohler Malcolm, Huber Lars C, Franzen Daniel P
Clinical Outcome of ALK-Positive Non-Small Cell Lung Cancer (NSCLC) Patients with De Novo EGFR or KRAS Co-Mutations Receiving Tyrosine Kinase Inhibitors (TKIs)
Schmid S, Diebold J, Jochum W, Reichegger H, Klingbiel D, Froesch P, Mark M, Rothschild S, Gautschi O, Früh M. Clinical Outcome of ALK-Positive Non-Small Cell Lung Cancer (NSCLC) Patients with De Novo EGFR or KRAS Co-Mutations Receiving Tyrosine Kinase Inhibitors (TKIs). J Thorac Oncol 2016
Dec 19, 2016Clinical Outcome of ALK-Positive Non-Small Cell Lung Cancer (NSCLC) Patients with De Novo EGFR or KRAS Co-Mutations Receiving Tyrosine Kinase Inhibitors (TKIs)
Dec 19, 2016J Thorac Oncol 2016
Schmid Sabine, Diebold Joachim, Jochum Wolfram, Reichegger Hermann, Klingbiel Dirk, Froesch Patrizia, Mark Michael, Rothschild Sacha, Gautschi Oliver, Früh Martin
Tubulocystic Carcinoma of the Kidney With Poorly Differentiated Foci: A Frequent Morphologic Pattern of Fumarate Hydratase-deficient Renal Cell Carcinoma
Smith S, Brimo F, Gill A, Osunkoya A, Magi-Galluzzi C, Sibony M, Williamson S, Nesi G, Picken M, Maclean F, Agaimy A, Cheng L, Epstein J, Reuter V, Tickoo S, Tomlins S, Tripodi S, Werneck da Cunha I, Trpkov K, Chen Y, Mehra R, Sirohi D, Ohe C, Cani A, Hovelson D, Omata K, McHugh J, Jochum W, Colecchia M, Amin M, Divatia M, Hes O, Menon S, Amin M. Tubulocystic Carcinoma of the Kidney With Poorly Differentiated Foci: A Frequent Morphologic Pattern of Fumarate Hydratase-deficient Renal Cell Carcinoma. Am J Surg Pathol 2016; 40:1457-1472.
Nov 1, 2016Tubulocystic Carcinoma of the Kidney With Poorly Differentiated Foci: A Frequent Morphologic Pattern of Fumarate Hydratase-deficient Renal Cell Carcinoma
Nov 1, 2016Am J Surg Pathol 2016; 40:1457-1472
Smith Steven C, Brimo Fadi, Gill Anthony J, Osunkoya Adeboye O, Magi-Galluzzi Cristina, Sibony Mathilde, Williamson Sean R, Nesi Gabriella, Picken Maria M, Maclean Fiona, Agaimy Abbas, Cheng Liang, Epstein Jonathan I, Reuter Victor E, Tickoo Satish K, Tomlins Scott A, Tripodi Sergio, Werneck da Cunha Isabela, Trpkov Kiril, Chen Ying-Bei, Mehra Rohit, Sirohi Deepika, Ohe Chisato, Cani Andi K, Hovelson Daniel H, Omata Kei, McHugh Jonathan B, Jochum Wolfram, Colecchia Maurizio, Amin Mitual, Divatia Mukul K, Hes Ondrej, Menon Santosh, Amin Mahul B
A 3D co-culture microtissue model of the human placenta for nanotoxicity assessment
Muoth C, Wick P, Jochum W, Manser P, Diener L, Kucki M, Gallud A, Loeschner K, Ehrlich N, Correia M, Monopoli M, Wichser A, Buerki-Thurnherr T. A 3D co-culture microtissue model of the human placenta for nanotoxicity assessment. Nanoscale 2016; 8:17322-17332.
Oct 6, 2016A 3D co-culture microtissue model of the human placenta for nanotoxicity assessment
Oct 6, 2016Nanoscale 2016; 8:17322-17332
Muoth Carina, Wick Peter, Jochum Wolfram, Manser Pius, Diener Liliane, Kucki Melanie, Gallud Audrey, Loeschner Katrin, Ehrlich Nicky, Correia Manuel, Monopoli Marco, Wichser Adrian, Buerki-Thurnherr Tina
Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer
Hasan Ali O, Diem S, Markert E, Jochum W, Kerl K, French L, Speiser D, Früh M, Flatz L. Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer. Oncoimmunology 2016; 5:e1231292.
Sep 19, 2016Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer
Sep 19, 2016Oncoimmunology 2016; 5:e1231292
Hasan Ali Omar, Diem Stefan, Markert Eva, Jochum Wolfram, Kerl Katrin, French Lars E, Speiser Daniel E, Früh Martin, Flatz Lukas
Rapid Intracranial Response to Osimertinib in a Patient with Epidermal Growth Factor Receptor T790M-Positive Adenocarcinoma of the Lung
Reichegger H, Jochum W, Förbs D, Hader C, Früh M. Rapid Intracranial Response to Osimertinib in a Patient with Epidermal Growth Factor Receptor T790M-Positive Adenocarcinoma of the Lung. Oncol Res Treat 2016; 39:461-3.
Jun 15, 2016Rapid Intracranial Response to Osimertinib in a Patient with Epidermal Growth Factor Receptor T790M-Positive Adenocarcinoma of the Lung
Jun 15, 2016Oncol Res Treat 2016; 39:461-3
Reichegger Hermann, Jochum Wolfram, Förbs Diana, Hader Claudia, Früh Martin