Jovana Cupovic
A replicating LCMV-based vaccine for the treatment of solid tumors.
Purde M, Cupovic J, Palmowski Y, Makky A, Schmidt S, Rochwarger A, Hartmann F, Stemeseder F, Lercher A, Abdou M, Bomze D, Besse L, Berner F, Tüting T, Hölzel M, Bergthaler A, Kochanek S, Ludewig B, Lauterbach H, Orlinger K, Bald T, Schietinger A, Schürch C, Ring S, Flatz L. A replicating LCMV-based vaccine for the treatment of solid tumors. Mol Ther 2023
Dec 5, 2023A replicating LCMV-based vaccine for the treatment of solid tumors.
Dec 5, 2023Mol Ther 2023
Purde Mette-Triin, Cupovic Jovana, Palmowski Yannick A, Makky Ahmad, Schmidt Sarah, Rochwarger Alexander, Hartmann Fabienne, Stemeseder Felix, Lercher Alexander, Abdou Marie-Therese, Bomze David, Besse Lenka, Berner Fiamma, Tüting Thomas, Hölzel Michael, Bergthaler Andreas, Kochanek Stefan, Ludewig Burkhard, Lauterbach Henning, Orlinger Klaus K, Bald Tobias, Schietinger Andrea, Schürch Christian M, Ring Sandra Stephanie, Flatz Lukas
Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment
Ring S, Spiegl M, Besse A, Bonilla W, Stemeseder F, Schmidt S, Orlinger K, Krebs P, Ludewig B, Wenger R, Hartmann F, Cupovic J, Onder L, Lütge M, Pérez Shibayama C, Gil Cruz C, Scandella E, De Martin A, Mörbe U, Flatz L. Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment. Nat Commun 2021; 12:4734.
Aug 5, 2021Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment
Aug 5, 2021Nat Commun 2021; 12:4734
Ring Sandra, Spiegl Matthias, Besse Andrej, Bonilla Weldy V, Stemeseder Felix, Schmidt Sarah, Orlinger Klaus K, Krebs Philippe, Ludewig Burkhard, Wenger Robert, Hartmann Fabienne, Cupovic Jovana, Onder Lucas, Lütge Mechthild, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Scandella Elke, De Martin Angelina, Mörbe Urs, Flatz Lukas
Distinct microbial communities colonize tonsillar squamous cell carcinoma.
De Martin A, Lütge M, Stanossek Y, Engetschwiler C, Cupovic J, Brown K, Demmer I, Broglie M, Geuking M, Jochum W, McCoy K, Stöckli S, Ludewig B. Distinct microbial communities colonize tonsillar squamous cell carcinoma. Oncoimmunology 2021; 10:1945202.
Jul 25, 2021Distinct microbial communities colonize tonsillar squamous cell carcinoma.
Jul 25, 2021Oncoimmunology 2021; 10:1945202
De Martin Angelina, Lütge Mechthild, Stanossek Yves, Engetschwiler Céline, Cupovic Jovana, Brown Kirsty, Demmer Izadora, Broglie Martina Anja, Geuking Markus B, Jochum Wolfram, McCoy Kathy D, Stöckli Sandro, Ludewig Burkhard
Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8 T cells
Cupovic J, Klenerman P, Engeler D, Krebs P, Scandella E, Oxenius A, Flatz L, Provine N, De Martin A, Cheng H, Lütge M, Colston J, Onder L, Ring S, Ludewig B. Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8 T cells. Nat Immunol 2021; 22:1042-1051.
Jul 15, 2021Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8 T cells
Jul 15, 2021Nat Immunol 2021; 22:1042-1051
Cupovic Jovana, Klenerman Paul, Engeler Daniel, Krebs Philippe, Scandella Elke, Oxenius Annette, Flatz Lukas, Provine Nicholas M, De Martin Angelina, Cheng Hung-Wei, Lütge Mechthild, Colston Julia M, Onder Lucas, Ring Sandra, Ludewig Burkhard
B cell zone reticular cell microenvironments shape CXCL13 gradient formation
Cosgrove J, Uguccioni M, Legler D, Lacey C, Coatesworth A, Polak W, Cupedo T, Manoury B, Thelen M, Stein J, Wolf M, Leake M, Timmis J, Ludewig B, Heller M, Venetz D, Taylor E, Novkovic M, Albrecht S, Pikor N, Zhou Z, Onder L, Mörbe U, Cupovic J, Miller H, Alden K, Thuery A, O'Toole P, Pinter R, Jarrett S, Coles M. B cell zone reticular cell microenvironments shape CXCL13 gradient formation. Nat Commun 2020; 11:3677.
Jul 22, 2020B cell zone reticular cell microenvironments shape CXCL13 gradient formation
Jul 22, 2020Nat Commun 2020; 11:3677
Cosgrove Jason, Uguccioni Mariagrazia, Legler Daniel F, Lacey Charles J, Coatesworth Andrew, Polak Wojciech G, Cupedo Tom, Manoury Bénedicte, Thelen Marcus, Stein Jens V, Wolf Marlene, Leake Mark C, Timmis Jon, Ludewig Burkhard, Heller Manfred, Venetz Daniel, Taylor Emily, Novkovic Mario, Albrecht Stefan, Pikor Natalia, Zhou Zhaoukun, Onder Lucas, Mörbe Urs, Cupovic Jovana, Miller Helen, Alden Kieran, Thuery Anne, O'Toole Peter, Pinter Rita, Jarrett Simon, Coles Mark C
Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis
Brenig R, Antoniades C, Wendon J, Heim M, Ludewig B, Weston C, Duong F, Semela D, Brand S, Boldanova T, Künzler-Heule P, Cupovic J, Besse L, Pérez Shibayama C, Singanayagam A, Geng A, Triantafyllou E, Pop O, Bernsmeier C. Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis. Life Sci Alliance 2019; 3
Dec 10, 2019Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis
Dec 10, 2019Life Sci Alliance 2019; 3
Brenig Robert, Antoniades Charalambos G, Wendon Julia, Heim Markus H, Ludewig Burkhard, Weston Christopher J, Duong François Ht, Semela David, Brand Stephan, Boldanova Tuyana, Künzler-Heule Patrizia, Cupovic Jovana, Besse Lenka, Pérez Shibayama Christian Ivan, Singanayagam Arjuna, Geng Anne, Triantafyllou Evangelos, Pop Oltin, Bernsmeier Christine
CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
Cheng H, Brutsche M, Jochum W, Schneider T, Rodriguez R, Tarantino I, Pikor N, Novkovic M, Bösch M, Cupovic J, Onder L, Ludewig B. CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses. J Allergy Clin Immunol 2018
Jan 31, 2018CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
Jan 31, 2018J Allergy Clin Immunol 2018
Cheng Hung-Wei, Brutsche Martin, Jochum Wolfram, Schneider Tino, Rodriguez Regulo, Tarantino Ignazio, Pikor Natalia, Novkovic Mario, Bösch Maximilian, Cupovic Jovana, Onder Lucas, Ludewig Burkhard
Stromal Cell Niches in the Inflamed Central Nervous System
Pikor N, Cupovic J, Onder L, Gommerman J, Ludewig B. Stromal Cell Niches in the Inflamed Central Nervous System. J Immunol 2017; 198:1775-1781.
Mar 1, 2017Stromal Cell Niches in the Inflamed Central Nervous System
Mar 1, 2017J Immunol 2017; 198:1775-1781
Pikor Natalia, Cupovic Jovana, Onder Lucas, Gommerman Jennifer L, Ludewig Burkhard
Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs
Gil Cruz C, Scandella E, Ikuta K, Cui G, Abe S, McCoy K, Geuking M, Lang P, Novkovic M, Cheng H, Cupovic J, Chai Q, Onder L, Pérez Shibayama C, Ludewig B. Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs. Nat Immunol 2016; 17:1388-1396.
Oct 31, 2016Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs
Oct 31, 2016Nat Immunol 2016; 17:1388-1396
Gil Cruz Cristina, Scandella Elke, Ikuta Koichi, Cui Guangwei, Abe Shinya, McCoy Kathy D, Geuking Markus B, Lang Philipp A, Novkovic Mario, Cheng Hung-Wei, Cupovic Jovana, Chai Qian, Onder Lucas, Pérez Shibayama Christian Ivan, Ludewig Burkhard
Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
Novkovic M, Turley S, Bocharov G, Stein J, Scandella E, Cremasco V, Bomze D, Abe J, Cupovic J, Onder L, Ludewig B. Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality. PLoS Biol 2016; 14:e1002515.
Jul 14, 2016Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
Jul 14, 2016PLoS Biol 2016; 14:e1002515
Novkovic Mario, Turley Shannon J, Bocharov Gennady, Stein Jens V, Scandella Elke, Cremasco Viviana, Bomze David, Abe Jun, Cupovic Jovana, Onder Lucas, Ludewig Burkhard
Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced Neuroinflammation
Cupovic J, Onder L, Gil Cruz C, Weiler E, Caviezel-Firner S, Pérez Shibayama C, Rülicke T, Bechmann I, Ludewig B. Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced Neuroinflammation. Immunity 2016; 44:622-33.
Feb 23, 2016Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced Neuroinflammation
Feb 23, 2016Immunity 2016; 44:622-33
Cupovic Jovana, Onder Lucas, Gil Cruz Cristina, Weiler Elke, Caviezel-Firner Sonja, Pérez Shibayama Christian Ivan, Rülicke Thomas, Bechmann Ingo, Ludewig Burkhard
Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage
Bhattacharya A, Arnold I, Flatz L, Xu H, Lang P, Aderem A, Takaoka A, Superti-Furga G, Colinge J, Ludewig B, Löhning M, Baazim H, Khamina K, Panse I, Hegazy A, Deigendesch N, Kosack L, Cupovic J, Kandasamy R, Hildebrandt A, Merkler D, Kühl A, Vilagos B, Schliehe C, Bergthaler A. Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage. Immunity 2015; 43:974-86.
Nov 17, 2015Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage
Nov 17, 2015Immunity 2015; 43:974-86
Bhattacharya Anannya, Arnold Isabelle, Flatz Lukas, Xu Haifeng C, Lang Philipp A, Aderem Alan, Takaoka Akinori, Superti-Furga Giulio, Colinge Jacques, Ludewig Burkhard, Löhning Max, Baazim Hatoon, Khamina Kseniya, Panse Isabel, Hegazy Ahmed N, Deigendesch Nikolaus, Kosack Lindsay, Cupovic Jovana, Kandasamy Richard K, Hildebrandt Andrea, Merkler Doron, Kühl Anja A, Vilagos Bojan, Schliehe Christopher, Bergthaler Andreas
Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4+ T cell-dendritic cell interactions
Moalli F, Cupovic J, Thelen F, Halbherr P, Fukui Y, Narumiya S, Ludewig B, Stein J. Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4+ T cell-dendritic cell interactions. J Exp Med 2014; 211:2507-17.
Dec 8, 2014Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4+ T cell-dendritic cell interactions
Dec 8, 2014J Exp Med 2014; 211:2507-17
Moalli Federica, Cupovic Jovana, Thelen Flavian, Halbherr Pascal, Fukui Yoshinori, Narumiya Shuh, Ludewig Burkhard, Stein Jens V
B cell homeostasis and follicle confines are governed by fibroblastic reticular cells
Cremasco V, Carroll M, Ludewig B, Wucherpfennig K, Harvey C, Cremasco F, Chang J, Schildberg F, Nieves-Bonilla J, Cupovic J, Onder L, Woodruff M, Turley S. B cell homeostasis and follicle confines are governed by fibroblastic reticular cells. Nat Immunol 2014; 15:973-81.
Aug 24, 2014B cell homeostasis and follicle confines are governed by fibroblastic reticular cells
Aug 24, 2014Nat Immunol 2014; 15:973-81
Cremasco Viviana, Carroll Michael C, Ludewig Burkhard, Wucherpfennig Kai, Harvey Christopher J, Cremasco Floriana, Chang Jonathan, Schildberg Frank A, Nieves-Bonilla Janice M, Cupovic Jovana, Onder Lucas, Woodruff Matthew C, Turley Shannon J
Mathematical models for CFSE labelled lymphocyte dynamics: asymmetry and time-lag in division
Luzyanina T, Cupovic J, Ludewig B, Bocharov G. Mathematical models for CFSE labelled lymphocyte dynamics: asymmetry and time-lag in division. J Math Biol 2013
Dec 13, 2013Mathematical models for CFSE labelled lymphocyte dynamics: asymmetry and time-lag in division
Dec 13, 2013J Math Biol 2013
Luzyanina Tatyana, Cupovic Jovana, Ludewig Burkhard, Bocharov Gennady
Asymmetry of Cell Division in CFSE-Based Lymphocyte Proliferation Analysis
Bocharov G, Luzyanina T, Cupovic J, Ludewig B. Asymmetry of Cell Division in CFSE-Based Lymphocyte Proliferation Analysis. Front Immunol 2013; 4:264.
Sep 2, 2013Asymmetry of Cell Division in CFSE-Based Lymphocyte Proliferation Analysis
Sep 2, 2013Front Immunol 2013; 4:264
Bocharov Gennady, Luzyanina Tatyana, Cupovic Jovana, Ludewig Burkhard
Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity
Chai Q, Hehlgans T, Stein J, Rülicke T, Thiel V, Luther S, Sparwasser T, Danuser R, Cupovic J, Pérez Shibayama C, Gil Cruz C, Scandella E, Onder L, Ludewig B. Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity. Immunity 2013; 38:1013-24.
Apr 25, 2013Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity
Apr 25, 2013Immunity 2013; 38:1013-24
Chai Qian, Hehlgans Thomas, Stein Jens V, Rülicke Thomas, Thiel Volker, Luther Sanjiv A, Sparwasser Tim, Danuser Renzo, Cupovic Jovana, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Scandella Elke, Onder Lucas, Ludewig Burkhard