Publikation

Developing a cosmetic series: Results from the ESSCA network, 2009-2018

Wissenschaftlicher Artikel/Review - 26.08.2020

Bereiche
PubMed
DOI

Zitation
Horton E, Weisshaar E, Rustemeyer T, Sánchez-Pérez J, Simon D, Schuttelaar M, Mahler V, John S, Gonçalo M, Giménez-Arnau A, Dickel H, Bircher A, Bauer A, Ballmer-Weber B, Geier J, Uter W, Wilkinson S. Developing a cosmetic series: Results from the ESSCA network, 2009-2018. Contact dermatitis 2020
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Contact dermatitis 2020
Veröffentlichungsdatum
26.08.2020
eISSN (Online)
1600-0536
Kurzbeschreibung/Zielsetzung

BACKGROUND
There is considerable variability across European patch test centres as to which allergens are included in local and national cosmetics series.

OBJECTIVES
To propose a standardized, evidence-based cosmetic series for Europe based on up-to-date analysis of relevant contact allergens.

METHODS
We collated data from the European Surveillance System on Contact Allergies (ESSCA) from 2009 to 2018 to determine which cosmetic allergens produce a high yield of contact allergy. Contact allergens with a prevalence of >0.3% that were considered relevant were included. Rare contact allergens were excluded if deemed no longer relevant or added to a supplemental cosmetic series for further analysis.

RESULTS
Sensitization prevalences of 39 cosmetic contact allergens were tabulated. Thirty of these allergens yielded >0.3% positive reactions and are therefore included in our proposed European cosmetic series. Six were considered no longer relevant and therefore excluded. Three were included in a supplementary European cosmetic series. An additional nine allergens were included in either the core or supplemental European cosmetic series following literature review.

CONCLUSION
We have derived a potential European cosmetic series based upon the above methods. This will require ongoing investigation based upon the changing exposure profiles of cosmetic allergens as well as new and evolving substances.