Publikation
Developing a cosmetic series: Results from the ESSCA network, 2009-2018
Wissenschaftlicher Artikel/Review - 26.08.2020
Horton Emma, Weisshaar Elke, Rustemeyer Thomas, Sánchez-Pérez Javier, Simon Dagmar, Schuttelaar Marie L A, Mahler Vera, John Swen Malte, Gonçalo Margarida, Giménez-Arnau Ana, Dickel Heinrich, Bircher Andreas, Bauer Andrea, Ballmer-Weber Barbara, Geier Johannes, Uter Wolfgang, Wilkinson S Mark
Bereiche
PubMed
DOI
Zitation
Art
Zeitschrift
Veröffentlichungsdatum
eISSN (Online)
Kurzbeschreibung/Zielsetzung
BACKGROUND
There is considerable variability across European patch test centres as to which allergens are included in local and national cosmetics series.
OBJECTIVES
To propose a standardized, evidence-based cosmetic series for Europe based on up-to-date analysis of relevant contact allergens.
METHODS
We collated data from the European Surveillance System on Contact Allergies (ESSCA) from 2009 to 2018 to determine which cosmetic allergens produce a high yield of contact allergy. Contact allergens with a prevalence of >0.3% that were considered relevant were included. Rare contact allergens were excluded if deemed no longer relevant or added to a supplemental cosmetic series for further analysis.
RESULTS
Sensitization prevalences of 39 cosmetic contact allergens were tabulated. Thirty of these allergens yielded >0.3% positive reactions and are therefore included in our proposed European cosmetic series. Six were considered no longer relevant and therefore excluded. Three were included in a supplementary European cosmetic series. An additional nine allergens were included in either the core or supplemental European cosmetic series following literature review.
CONCLUSION
We have derived a potential European cosmetic series based upon the above methods. This will require ongoing investigation based upon the changing exposure profiles of cosmetic allergens as well as new and evolving substances.