Publikation
and Prognosis in mCRPC Survival: Biology or Coincidence?
Wissenschaftlicher Artikel/Review - 04.01.2019
Rebello Richard J, Oing Christoph, Gillessen Sommer Silke, Bristow Robert G
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Cell-free circulating tumor DNA (ctDNA) or circulating tumor cell (CTC) assays are potentially powerful in the treatment of metastatic castration-resistant prostate cancer (mCRPC). A new study suggests that mutation of TP53 supersedes AR in predicting mCRPC survival. A role for TP53 mutation as a driver for mCRPC remains unexplored.See related article by De Laere et al., p. 1766.