[Total thyroidectomy in patients with amiodarone-induced hyperthyroidism: when does the risk of conservative treatment exceed the risk of surgery?]

Publikation

[Total thyroidectomy in patients with amiodarone-induced hyperthyroidism: when does the risk of conservative treatment exceed the risk of surgery?]

Wissenschaftlicher Artikel/Review - 01.02.2014

Meerwein C, Vital D, Greutmann M, Schmid C, Huber Gerhard

Zitation

Meerwein C, Vital D, Greutmann M, Schmid C, Huber G. [Total thyroidectomy in patients with amiodarone-induced hyperthyroidism: when does the risk of conservative treatment exceed the risk of surgery?]. HNO 2014; 62:100-5.

Art

Wissenschaftlicher Artikel/Review (Deutsch)

Zeitschrift

HNO 2014; 62

Veröffentlichungsdatum

01.02.2014

eISSN (Online)

1433-0458

Seiten

100-5

Kurzbeschreibung/Zielsetzung

Amiodarone plays a pivotal role in the treatment of ventricular and supraventricular arrhythmias. However, amiodarone-induced hyperthyroidism (AIH) is one of the most feared complications, which necessitates interdisciplinary treatment and careful balancing of the risks of conservative treatment against those of total thyroidectomy. In this article we discuss the pharmacological aspects of amiodarone and its diverse effects on the thyroid. Furthermore, we present diagnostic and therapeutic strategies and report our positive experiences with total thyroidectomy in patients with AIH. Particularly in patients for whom continuation of amiodarone treatment is compulsory, a well-timed total thyroidectomy is a reliable therapeutic option, with minimal complication rates and immediate amelioration of symptoms.