Publikation

Association of aortic root calcification severity with the extent of coronary artery calcification assessed by calcium-scoring dual-source computed tomography

Wissenschaftlicher Artikel/Review - 06.06.2015

Bereiche
PubMed
DOI

Zitation
Hu X, Frellesen C, Kerl J, Bauer R, Beeres M, Bodelle B, Lehnert T, Vogl T, Wichmann J. Association of aortic root calcification severity with the extent of coronary artery calcification assessed by calcium-scoring dual-source computed tomography. Eur J Radiol 2015; 84:1910-4.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Eur J Radiol 2015; 84
Veröffentlichungsdatum
06.06.2015
eISSN (Online)
1872-7727
Seiten
1910-4
Kurzbeschreibung/Zielsetzung

PURPOSE
To investigate the association between aortic root calcification (ARC) and coronary artery calcification (CAC) assessed by coronary artery calcium-scoring dual-source computed tomography (DSCT).

MATERIALS AND METHODS
We retrospectively analyzed 143 consecutive patients who underwent coronary artery calcium-scoring during coronary DSCT angiography. 57 patients had findings of ARC on calcium-scoring scans. ARC volume (ARCV) and Agatston coronary artery calcium score (CACS) were calculated. Chi-square test was used to assess differences of categorical variables between patients with and without ARC. Statistical significances between both groups were assessed with the independent-Sample t test.

RESULTS
Compared with patients without ARC (n=86), patients with ARC (n=57) showed a significantly higher presence of CAC (87.7% vs. 24.4%; P<0.001), and a higher mean CACS (700.6 ± 941.2 vs. 256.4 ± 724.3; P=0.009) in patients with CAC. Patients with a calculated ARCV > 40 mm(3) (n=32) showed significantly higher rates of severe CAC (56.3% vs. 24.0%; P=0.014) compared with patients with an ARCV< 40 mm(3) (n=25). Compared with patients without CAC (n=42), patients with CAC (n=101) showed a significantly higher presence of ARC (83.3% vs. 50.5%; P<0.001) and a higher mean ARCV (95.4 ± 116.2mm(3) vs. 29.7 ± 33.0 mm(3); P=0.003). Severe CAC (n=24) correlated with an increased mean ARCV (122.3 ± 148.8mm(3)) compared to patients with minimal to moderate CAC (n=33, mean ARCV: 61.9 ± 64.8mm(3); P<0.05).

CONCLUSIONS
The extent of ARC is directly associated with the presence and degree of CAC on calcium-scoring scans during coronary DSCT angiography.