Publikation

Galactorrhoea and pituitary mass: a typical prolactinoma?

Wissenschaftlicher Artikel/Review - 01.04.2000

Bereiche
PubMed

Zitation
Brändle M, Schmid C. Galactorrhoea and pituitary mass: a typical prolactinoma?. Postgraduate medical journal 2000; 76:232-4.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Postgraduate medical journal 2000; 76
Veröffentlichungsdatum
01.04.2000
ISSN (Druck)
0032-5473
Seiten
232-4
Kurzbeschreibung/Zielsetzung

A 21 year old woman presenting with galactorrhoea, hyperprolactinaemia, and a pituitary mass on magnetic resonance imaging (MRI) is described who was referred to us before planned pituitary surgery. Although a thorough history did not suggest hypothyroidism, laboratory studies revealed profound primary hypothyroidism. At that time, pituitary MRI showed homogeneous enlargement of the pituitary gland consistent with pituitary hyperplasia due to primary hypothyroidism. With thyroid hormone replacement therapy the galactorrhoea resolved, concentrations of prolactin and thyroid hormones returned to normal, and the pituitary shrunk to normal size within two months. This case illustrates that primary hypothyroidism can present only with galactorrhoea and pituitary mass, and should therefore be considered in the differential diagnosis of hyperprolactinaemia and pituitary enlargement.