Angiogenesis and lymphangiogenesis are downregulated in primary breast cancer

Publikation

Angiogenesis and lymphangiogenesis are downregulated in primary breast cancer

Wissenschaftlicher Artikel/Review - 18.08.2009

Boneberg E-M, Senn H-J, Otto F, Dupont-Lampert V, Beer G M, Füzesi L, Steininger H, Öhlschlegel Christian, Hoefer M M, Legler D F, Fürstenberger G

Zitation

Boneberg E, Senn H, Otto F, Dupont-Lampert V, Beer G, Füzesi L, Steininger H, Öhlschlegel C, Hoefer M, Legler D, Fürstenberger G. Angiogenesis and lymphangiogenesis are downregulated in primary breast cancer. Br J Cancer 2009; 101:605-14.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Br J Cancer 2009; 101

Veröffentlichungsdatum

18.08.2009

eISSN (Online)

1532-1827

Seiten

605-14

Kurzbeschreibung/Zielsetzung

Angiogenesis and lymphangiogenesis are considered to play key roles in tumour growth, progression and metastasis. However, targeting tumour angiogenesis in clinical trials showed only modest efficacy. We therefore scrutinised the concept of tumour angiogenesis and lymphangiogenesis by analysing the expression of crucial markers involved in these processes in primary breast cancer.