Azithromycin alters spatial and temporal dynamics of airway microbiota in idiopathic pulmonary fibrosis.

Publikation

Azithromycin alters spatial and temporal dynamics of airway microbiota in idiopathic pulmonary fibrosis.

Wissenschaftlicher Artikel/Review - 22.05.2023

Gijs Pieter-Jan, Daccord Cécile, Bernasconi Eric, Brutsche Martin, Clarenbach Christian F, Hostettler Katrin E, Guler Sabina A, Mercier Louis, Ubags Niki, Funke-Chambour Manuela, von Garnier Christophe

Zitation

Gijs P, Daccord C, Bernasconi E, Brutsche M, Clarenbach C, Hostettler K, Guler S, Mercier L, Ubags N, Funke-Chambour M, von Garnier C. Azithromycin alters spatial and temporal dynamics of airway microbiota in idiopathic pulmonary fibrosis. ERJ Open Res 2023; 9

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

ERJ Open Res 2023; 9

Veröffentlichungsdatum

22.05.2023

ISSN (Druck)

2312-0541

Kurzbeschreibung/Zielsetzung

High bacterial burden in the lung microbiota predicts progression of idiopathic pulmonary fibrosis (IPF). Azithromycin (AZT) is a macrolide antibiotic known to alter the lung microbiota in several chronic pulmonary diseases, and observational studies have shown a positive effect of AZT on mortality and hospitalisation rate in IPF. However, the effect of AZT on the lung microbiota in IPF remains unknown.