Publikation
Temozolomid in der Behandlung maligner Gliome
Wissenschaftlicher Artikel/Review - 01.01.2003
Hundsberger Thomas, Koch Dorothee, Klimpe Sven, Schlegel Uwe
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Kurzbeschreibung/Zielsetzung
Temozolomide is an orally administered, alkylating agent with approval for recurrent and progressive malignant gliomas. Here we review the pharmacological properties of temozolomide, its possible side effects and current indications for the treatment of malignant gliomas. Some current treatment trials on temozolomide are discussed, which may have an impact on its role in future Neuro-Oncology.