Publikation
Intravascular ultrasonic comparative analysis of degree of intimal hyperplasia produced by four different stents in the coronary arteries
Wissenschaftlicher Artikel/Review - 15.12.2004
Hoffmann Rainer, Weber Christian, Langenberg Roswitha, Franke Andreas, Iofina Ekatarina, Blindt Rüdiger, Haager Philipp K., Ortlepp Jan R, Radke Peter W, Hanrath Peter
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Kurzbeschreibung/Zielsetzung
Intravascular ultrasound studies were performed at angiographic follow-up on 121 native coronary lesions treated with 1 bare metal stent (n = 50), high-dose dexamethasone-eluting stents (n = 18), non-polymer-based paclitaxel-eluting stents (n = 18), or sirolimus-eluting stents (n = 35). Paclitaxel- and sirolimus-eluting stents reduced mean intimal hyperplasia thickness compared with bare metal stents by 49% and 90% (p = 0.048 and p <0.001), respectively, whereas mean intimal hyperplasia thickness treated with dexamethasone-eluting stents was similar to those lesions treated with bare metal stents.