Women with HIV transitioning through menopause: Insights from the Swiss HIV Cohort Study (SHCS)
Wissenschaftlicher Artikel/Review - 23.02.2022
Hachfeld Anna, Abela Irene, Sultan-Beyer Leila, Polli Christian, Babouee Flury Baharak, Darling Katharine, Tarr Philipp, Calmy Alexandra, Stute Petra, Atkinson A, Aebi-Popp Karoline
Objectives: We aimed to assess prevalence and age at menopause, identify factors associated with early menopause and explore the provision and utilization ofhealthcare in women living with HIV in Switzerland.
Methods: This was a retrospective Swiss HIVCohort Study analysisfrom January 2010 to December 2018. Descriptive statistics to characterise the population and menopause onset. Logistic regression analysis to identify risk factors for earlymenopause.
Results: Of all women in the SHCS, the proportion of postmenopausal women tripled from 11.5% (n = 274) in 2010 to 36.1% (n = 961) in 2018. The median age at menopause was 50 years. Early menopause (< 45 years) occurred in 115 (10.2%) women and premature ovarian insufficiency (POI) (< 40 years) in 23 (2%) women. Early menopause was associated with black ethnicity (52.2% vs. 21.6%, p < 0.001), but not with HIV acquisition mode, CDC stage, viralsuppression, CD4